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Joined May 2009
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DruMouser retweeted
I'm a cardiologist. I've held dying hearts in my hands in the cath lab at 3 AM. And I need to tell you something that changes everything about how we prevent heart attacks. For decades, the entire field was built on one target: lower LDL cholesterol. Statins save lives — that's settled science. But too many of my patients did everything right — took their statins, hit their numbers, lived clean — and still ended up on my table with a ruptured artery. We were treating the smoke while the fire kept burning. The fire is inflammation. And the evidence is now overwhelming. The CANTOS trial proved it first — lowering inflammation independent of cholesterol reduced cardiac events. But the newer data is what keeps me up at night. AI-enhanced CT angiography can now detect inflamed arteries by measuring changes in the fat surrounding your coronary vessels — the perivascular fat attenuation index. Higher inflammation in the fat around even one artery independently predicts cardiac death. When multiple arteries show inflammation, the risk multiplies dramatically — even in patients whose cholesterol looks perfect. This isn't theoretical. This is measurable. Right now. On a scan you can get this month. Low-dose colchicine — a drug that's been around for centuries for gout — is now FDA-approved specifically for reducing cardiovascular events. It works by quieting the inflammatory cascade that destabilizes the plaque sitting in your arteries. A pill that costs pennies is saving lives the statins couldn't reach. And the next wave is already in Phase 3 trials. Ziltivekimab — an IL-6 inhibitor — targets the central inflammatory pathway driving atherosclerosis. Phase 2 data showed a 90% reduction in hsCRP. The ZEUS cardiovascular outcomes trial is enrolling now, with results expected late 2026 into 2027. If positive, anti-inflammatory therapy will become standard in managing heart disease alongside lipid-lowering. The era of inflammation-targeted cardiology is arriving. But it goes deeper than drugs. AI is now predicting heart failure and cardiac events 5 years before symptoms — integrating CT imaging, electronic health records, and genetic data with accuracy that jumps far beyond traditional risk calculators. And polygenic risk scores — a simple genetic test that flags inherited cardiovascular risk — are now formally recognized as a risk-enhancing factor in the 2026 ACC/AHA guidelines. A single blood draw can reveal risk that's been silently building since birth. Decades before the first chest pain. Here's what this means for you right now — today: Ask your doctor for a high-sensitivity CRP test. It's cheap, routine, and measures the systemic inflammation that standard cholesterol panels completely miss. You can have perfect LDL and inflamed arteries that are quietly preparing to rupture. If your hsCRP is elevated, discuss low-dose colchicine with your physician. It's FDA-approved for exactly this. Push for a coronary CT angiography with AI plaque and inflammation analysis if you have risk factors. This isn't the stress test your parents got. This is 3D visualization of your actual arteries — with AI quantifying not just how much plaque you have, but what kind it is and whether the surrounding tissue is inflamed. Consider polygenic risk score testing — especially with a family history of early heart disease. It's now guideline-supported. And the foundation that never changes: move daily, eat real food, sleep 7-9 hours, manage stress, and know your numbers — ApoB, Lp(a), hsCRP, fasting insulin. I left Iran as a child with nothing. I rebuilt everything in a country that gave me the freedom to become a physician. I've spent twenty years watching patients get second chances. The ones who haunt me aren't the ones who died on my table. They're the ones who survived but never acted on what the science was telling them — years before the event that didn't have to happen. You can have perfect cholesterol and still have a heart attack. Inflammation plus genetics can drive plaque rupture in arteries that look "fine" on a standard panel. The myth that normal cholesterol means you're safe has cost more lives than I can count. We now have the tools to detect the fire — not just the smoke. AI to see it. Genetics to predict it. Drugs to quiet it. And the ancient basics — movement, real food, sleep, purpose — to prevent it from starting. Prevention is the new cure. And the science to make it real is no longer coming. It's here.
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DruMouser retweeted
May 27
Money OS: Inside The Machine Behind Modern Finance w. Porter Stowell & Audie Sheridan x.com/i/broadcasts/1YxNrrWvk…

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DruMouser retweeted
8 Oct 2025
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4 Sep 2025
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DruMouser retweeted
Everyone over 30 blames weight gain, brain fog, & fatigue on "getting older." Turns out it's not your metabolism or your age... It's your lymphatic system that's completely backed up after years of neglect. Here's how to flush it clean and feel 20 again:
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DruMouser retweeted
22 Jun 2025
The @Tesla_AI robotaxi launch begins in Austin this afternoon with customers paying a $4.20 flat fee!
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DruMouser retweeted
LESSON: Always think of everything in life as a bell curve. Most people are in the middle. On each side is a "fringe" all the way from hate to love. Low to high, every emotion every feeling every opinion.
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30 Dec 2022
Some/We need to go play in the dirt and hug a tree…
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DruMouser retweeted
today i learned that hippos which are 4,000 pounds can't swim they just run underwater at 40 miles per hour and i dont know if blockchain will ever really compete w that
31 Mar 2022
A hippo chasing a speed boat in zambia..The butterfly stroke or hippo chase stroke is quite evident here.with his weight, taking such long leaps is absolutely breathtaking..👆 #wildlifephotography #naturelovers
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7 Feb 2022
Island fever
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12 Nov 2021
“You are not controlling the storm. And you are not lost in it. You are the storm.” (Thank u @lexfridman for sharing tnis wonderful #SamHarris quote…. #soothing #wisdom
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24 Nov 2020
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I assigned the green bean casserole to Helen. The latticework on her apple pie ruins my table photos.
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DruMouser retweeted
6 Aug 2020
Women have twice as many pain receptors on their bodies than men. But, a much higher pain tolerance.
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6 Aug 2020
I had such a great time on #Moesh! @4everBrandy & I had this really great chemistry; playing Moesha’s BFF was hip, exciting and fun:) and great memories! 🤩🥰 #moesha #bff #haley #bridgewood #brandy #moeshaandhaley 👩🏾‍🤝‍👩🏻 #upn #the90s #sitcom Moesha is airing on @netflix now!!!!
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23 Jul 2020
Congratulations @sagaftra 👏🏼 #biggains #sagaftra #contracts
23 Jul 2020
SAG-AFTRA members ratify 2020 TV/Theatrical Contracts by a vote of 74.22% to 25.78%: bit.ly/2OQaWAd
4 Apr 2020
Dear #Nurses, #doctors, all #healthcareworkers - from the bottom of my heart, thank you. #humbled #grateful
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31 Mar 2020
30 Mar 2020
Loyalty is rare. If you find it, keep it.
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