#EULAR2026: GCA & Takayasu, Shared Pathways, Different Ages?
Two prototypes, one spectrum.
TAK: CD8 cytotoxic injury, prominent fibrosis
GCA: macrophage-driven, self-renewing lesions
Shared IL-6/JAK response; TNFi only in TAK
from Weyand, Tomelleri, Direskeneli
@ElvisHysa