lab of fasting nutrigenomics, liver biology and gene expression @HebrewU

Joined December 2017
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I'm beyond excited/thrilled/honored to have received the #ERCStG grant. Thanks @ERC_Research WE ARE RECRUITING: ๐Ÿ‘ฉโ€๐Ÿ”ฌ #postdocs ๐Ÿ‘ฉโ€๐ŸŽ“ #PhD students ๐Ÿ‘ฉโ€๐Ÿ’ผ a lab manager Details at ido-goldstein-lab.com We study #fasting #chromatin #transcription #liver #IntermittentFasting
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If you are in #ENDO2026 and would like to hear the newest from our lab, join me for what is sure to be a great session: "Pioneering Metabolism: The Mangelsdorf Legacy and Beyond" Room W183A at 4:30pm.
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Ido Goldstein retweeted
ื’ืื•ื•ื” ืœืคืงื•ืœื˜ื”! ืคืจื•ืคโ€™ ืขื™ื“ื• ื’ื•ืœื“ืฉื˜ื™ื™ืŸ ืžื”ืžื›ื•ืŸ ืœื‘ื™ื•ื›ื™ืžื™ื”, ืžื“ืขื™ ื”ืžื–ื•ืŸ ื•ืชื–ื•ื ื” ื–ื›ื” ื‘ืคืจืก ื”ื™ื•ืงืจืชื™ ืฉืœ European Society of Endocrinology ืขืœ ืชืจื•ืžืชื• ืœืื ื“ื•ืงืจื™ื ื•ืœื•ื’ื™ื” ื‘ืกื™ืกื™ืช. ืžื—ืงืจื• ื—ื•ืฉืฃ โ€œื–ื™ื›ืจื•ืŸ ืžื˜ื‘ื•ืœื™โ€ ื‘ื›ื‘ื“ ื‘ืฆื•ื ืœืกื™ืจื•ื’ื™ืŸ ื•ื”ื’ื‘ืจืช ื™ืฆื™ืจืช ื’ื•ืคื™ ืงื˜ื•ืŸ . @goldstein_lab ๐Ÿ“ทJasper Ehrich
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Ido Goldstein retweeted
Our paper "Reversible and Causal Epigenetic Information Loss in Liver Aging and Disease" is out! Thanks to Roni and Naor for the hard work, and to our great collaborators @goldstein_lab and Noga Korenfeld. Links in the first reply
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Ido Goldstein retweeted

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A very useful review @NatRevGastroHep
An appraisal of mouse models for MASLD and MASH-associated HCC nature.com/articles/s41575-0โ€ฆ
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Tenured and promoted to Associate Professor ๐Ÿฅ‚ ๐ŸŽ‰ Big thanks to all those who supported and helped me along the way. In the picture - me during my PhD years when I learned about Publish or Perish
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This Review has been taking shape in my mind for a long time and I felt this is the perfect time to write it. It found a perfect home too: @NatureRevEndo. We summarize the hormonal control of the hepatic fasting response and describe how hormones cooperate rdcu.be/eYjH8
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To all #NuclearReceptors researchers! Iโ€™m Team Lead for this topic, and currently planning NR sessions for #ENDO2026 in Chicago. ๐Ÿ“ŒIf you have unpublished or recently published exciting data that youโ€™d like to share please get in touch! ๐Ÿ“ŒSpecially ECRs and underrepresented Rs
Behind the Scenes: ENDO 2026 Session Submissions | Our team invites you to submit your session suggestions and symposium proposals to share what you want to see at ENDO 2026. Watch our video: bit.ly/47vfV2B #ENDO2026
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Join us as a PI in the institute of biochemistry @HUJIAgri! We are looking for applicants doing metabolism research and research into the biology of metabolic tissues (adipose tissue, liver, pancreas, muscle etc.) Full details in the link ๐Ÿ‘‡ en.hafakulta.agri.huji.ac.ilโ€ฆ

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Ido Goldstein retweeted
๐Ÿ“ข Read our new bioRx in colab with Gordon Hager NIH @PabloFuentesP #FRecio @aguslafuent @PresmanLab @WaghKaustubh #IGoldstein et al where we found glucocorticoid receptor GR self-assembly, chromatin binding & activity is modulated by bile acids binding to a novel druggable site
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Thanks to @Trends_Endo_Met and Ganna Panasyuk for highlighting our recent study about #fasting, #enhancers and #ppara
Online Now: Enhancer binding as a KEysTONE of fasting response dlvr.it/TJPbkC #trends #endocrinology #metabolism
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Ido Goldstein retweeted
5 days to register to our EMBO Workshop! Stellar panel of invited speakers and many slots for talks selected from the abstracts. Come and join us this April in sunny ๐ŸŒ…Costa Brava๐ŸŒ… for 3 days of frontier research in #liver and #pancreas disease! tinyurl.com/EWLiverPancreas

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Ido Goldstein retweeted
๐Ÿ“ฃ Hiring, please forward widely!! Two postdoc openings to work on genomics of diabetes 1. computational regulatory genomics/statistical genetics. 2. Experimental cell-based modeling DM if interested @CRGenomica shorturl.at/O3wMi shorturl.at/ieyZy

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Ido Goldstein retweeted
Please join us for 3 exciting days of science linking up the liver & pancreas research communities! Co-organised by @1jorgeferrer @VallierLab @LickertHeiko & Emma Anderson #livertwitter #islets #masld #diabetes
Apply now for EMBO Workshop on Liver and pancreas in metabolic disease: from pathways to therapies 02 โ€“ 04 April 2025 in Sant Feliu de Guรญxols (Girona), Spain ๐Ÿ“œ Registration deadline: 14 February 2025 meetings.embo.org/event/25-lโ€ฆ #EMBOliverPancreas
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We just published what is is possibly the most important discovery from our lab yet! We found that the liver 'remembers' past fasting events and this positively affects its future response to fasting. We found a great home to this study @NAR_Open track.smtpsendmail.com/90321โ€ฆ
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Would not be possible without our great collaborators @Toxalim_E01 and the generous support of @ERC_Research
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Ido Goldstein retweeted
Refeeding after #fasting can lead to a "#FatOvershoot." @goldstein_lab @cumminslab &co examine the kinetics of #refeeding-induced transcriptional & chromatin changes, revealing a #lipogenic overshoot program regulated by the TF LXRฮฑ #PLOSBiology plos.io/4eukvi5
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Lipogenesis genes and their associated enhancers markedly overshoot above pre-fasting levels and this is dictated by liver X receptor ฮฑ. These findings unravel the mechanism behind the long-known phenomenon of refeeding fat overshoot. @HebrewU @HUJIAgri @HebrewU_Europe 2/2
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