@ireceptorgw is pleased to announce the availability of the data from Rawat et al., ~280M annotated #FAIR #AIRR TCRs now available through the @airr_community #AIRRDataCommons. medrxiv.org/content/10.1101/โฆ
15 Dec 2024
Extremely pleased to share our new work in collaboration with the @Bruskolab lab where we leveraged one of the largest TCRbeta sequencing datasets to identify T1D-associated TCR-based signatures. Paper link and ๐งต are below. Incredible work led by @puneet021192.
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6 Feb 2025
Great to be collaborating with @victorgreiff and colleagues on this new repository and new study. Looking forward to continuing to grow the @airr_community #AIRRDataCommons and provide more #FAIR #AIRRseq data to the research community!
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6 Feb 2025
The iReceptor team is pleased to announce a new repository and a new study in the @airr_community #AIRRDataCommons in collaboration with @victorgreiff @KhangLeQuy @ISnapkov @mchernigovskaia and @jakegalson.
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29 Oct 2024
If you are interested in sharing #T1D #AIRRseq data in the @airr_community #AIRRDataCommons, please reach out to the #T1D #AIRRseq consortium members @ireceptorgw, @bcorrie, @Bruskolab, Aaron Michels @CUAnschutz, @thesugarscience, @BonamiRachel, @StephanieJHanna.
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29 Oct 2024
Eighth #T1D #AIRRseq study available in @airr_community #AIRRDataCommons - Paired chain data from Eugster et al., "Physiological and pathogenic T cell autoreactivity converge in type 1 diabetes" (nature.com/articles/s41467-0โฆ) available through gateway.ireceptor.org
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18 Jun 2024
More #FAIR #T1D #AIRRseq data in @airr_community
#AIRRDataCommons through @ireceptorgw. 4.3M sequences from Culina et al "Islet-reactive CD8 T cell frequencies in the pancreas, but not in blood, distinguish type 1 diabetic patients from healthy donors"
science.org/doi/10.1126/sciiโฆ
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7 Dec 2023
Exciting to add a fourth #T1D #AIRRseq data set (including subject #MHC) to the #AIRRDataCommons from Anderson et al. "Human islet T cells are highly reactive to preproinsulin in type 1 diabetes" pnas.org/doi/full/10.1073/pnโฆ in collaboration with @Bruskolab @thesugarscience and others
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16 Aug 2023
We are happy to announce a third #SingleCell #AIRRseq study available in the @airr_community #AIRRDataCommons. #TCell #SingleCell and #GEX data from @Minervina_Asya et al. nature.com/articles/s41590-0โฆ added and searchable through @ireceptorgw
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4 Aug 2023
Great to be working with the broader community on sharing #AIRRseq data in the @airr_community #AIRRDataCommons - over 5 billion annotated sequences (including clone and single-cell data) available for search, analysis, and download through @ireceptorgw.
4 Aug 2023
July @ireceptorgw update: 3 paper and 2 preprint citations, with a focus around #anitbody search/discovery and #AIRRseq #immune #repertoire clustering, network analysis, #AI/#ML. The power of Billions of #AIRRseq annotated sequences in the @airr_community #AIRRDataCommons
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4 Aug 2023
July @ireceptorgw update: 3 paper and 2 preprint citations, with a focus around #anitbody search/discovery and #AIRRseq #immune #repertoire clustering, network analysis, #AI/#ML. The power of Billions of #AIRRseq annotated sequences in the @airr_community #AIRRDataCommons
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5 Jul 2023
June update - 3 new papers citing @ireceptorgw as a source for #FAIR #AIRRseq data reuse from @airr_community #AIRRDataCommons. Data reuse trending towards #ML and #EpitopeSpecifity - glad @ireceptorgw has been helpful!!! ๐งต
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29 Jun 2023
How about @ireceptorgw and the @airr_community #AIRRDataCommons with new #singlecell #BCR #TCR capabilities. Only a few #singlecell studies now but over 80 bulk #AIRRseq studies and we expect #singlecell to catch up.
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5 Jun 2023
We are happy to announce a second #SingleCell #AIRRseq study available in the @airr_community #AIRRDataCommons. #SingleCell and #GEX data from Wen et al. nature.com/articles/s41421-0โฆ added to the already existing #AIRRseq study, searchable through @ireceptorgw
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11 May 2023
Happy to have worked with @Hamad_JHU_Lab in utilizing @airr_community #AIRRDataCommons and @ireceptorgw to explore the frequency of public #CDR3 from #BCell and #TCell data. The power of #FAIR #AIRRseq data!
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1 May 2023
@ireceptorgw is pleased to announce the addition of a new repository and new #T1D study in the @airr_community #AIRRDataCommons. In collaboration with @prak_nina, 124 repertoires and 1.1M rearrangements from @TheHPAP.
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6 Apr 2023
@thesugarscience is pleased to have initiated and facilitated the build of the first #T1Drepository! After @ireceptorgw's new update with @bruskolab's first study there are 73.2 million sequences (602 repertoires) now available.
๐: tinyurl.com/2p8empdx@airr_coโฆ
#AIRRDataCommons
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5 Apr 2023
New update to @ireceptorgw's #T1D #repository! @Bruskolab's first study is now up, bringing the total number of sequences in the #T1Drepository to 73.2 million (602 repertoires).
Direct link to the new study uploaded: tinyurl.com/2p8empdx
@airr_community #AIRRDataCommons
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4 Apr 2023
A second #T1D study has been added to the @airr_community #AIRRDataCommons, searchable through gateway.ireceptor.org. 6.9M annotated #TCR/#BCR from Seay et al "Tissue distribution and clonal diversity of the T and B cell repertoire in type 1 diabetes" insight.jci.org/articles/vieโฆ
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20 Mar 2023
We continue to work towards a truly global #AIRRDataCommons of #tcell #bcell and #singlecell #immunology data based on #FAIR principles using @airr_community data sharing standards.
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7 Mar 2023
Great insight: "...a data commons is a partnership between the data scientists developing and supporting the commons and the disciplinary scientists with the research challenges." @airr_community #AIRRStandards @ireceptorgw makes the #AIRRDataCommons the resource that it is!
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