ProBioGen management / board background — condensed
ProBioGen AG is a Berlin-based CDMO and technology provider, originally a Charité spin-out, focused on cell-line engineering, process development, GMP manufacturing, viral vaccines, viral vectors, antibodies, proteins, and gene/cell-therapy manufacturing support.
Executive team
Dr. Alfred Merz — CEO
Merz joined ProBioGen in 2024 as COO and interim CEO, then became full CEO as of April 2025. His profile is classic industrial pharma operations: more than 30 years in manufacturing, operational excellence and strategy, including Bayer and Novartis in Europe and the U.S.
Dr. Simon Johannes Bulling — COO, newly joined
Bulling is the key recent appointment.
ProBioGen announced him on 21 April 2026, effective 15 April 2026, as COO. His mandate is to lead the operational business and oversee manufacturing across ProBioGen’s portfolio: proteins, viral vectors, cell and gene therapy. His background includes Celonic, Recipharm, Rentschler Biopharma, Vetter Pharma and Sandoz, with experience in sterile fill-finish, drug substance, drug product, GMP scale-up and multi-site operations.
Dr. Volker Sandig — CSO
Long-term scientific backbone: with ProBioGen since 2000, initiated the company’s cell-line development program, co-inventor of key technologies including AGE1 designer cell lines, GlymaxX and DirectedLuck, and works on viral-vector manufacturing and RNA-delivery platforms. Before ProBioGen, he worked at Merck Research Laboratories in the U.S. on adenoviral/vectored vaccine manufacturing systems.
Andrea Hauptmann — CFO
With ProBioGen since 2009, CFO since 2021, responsible for financial reporting, controlling, funding, cash management and financial risk management.
Dr. Gabriele Schneider — CBO
With ProBioGen since 2002; CBO since 2017; leads business development, commercial, marketing and communications strategy.
Supervisory board — notable profiles
Dr. Wafik Bardissi — Chairman
Chairman and CEO of Minapharm Pharmaceuticals, ProBioGen’s parent-company environment. He founded what ProBioGen describes as the first state-of-the-art biotech manufacturing operation in Africa/MENA in 2001 and signed the deal to acquire ProBioGen in 2010.
His profile also includes medicine/surgery, business IT, operational research, decision sciences and AI.
Importantly, ProBioGen states that in 2010 he was honored with the Knighthood / cavalry of the Pontifical Equestrian Order of St. Gregory the Great by Pope Benedict XVI for pioneering social work. ‼️
Dr. Shaheer Bardissi
Co-CEO and executive board member at Minapharm. His focus is immuno-oncology, vaccines, cell- and gene-based therapies, and expansion of Minapharm’s biologics portfolio across Africa. He previously worked at BioNTech and holds a PhD from Johannes Gutenberg University Mainz focused on gene-based immunotherapy.
Amr Shabrawishi — Co-Chairman
Vice-chairman of Minapharm; also chairman/CEO of Shabrawishi Hospital in Cairo, chairman of Egyptian Biological Science Co. for blood/plasma collection and processing, and board member of Viral Inactivated Plasma Systems, a Swiss plasma viral inactivation/fractionation company.
Prof. Dr.-Ing. Wiltrud Treffenfeldt
Industrial biotech/chemicals profile: Dow, Dow AgroSciences, Degussa/Evonik; CTO for Europe/Middle East/Africa/India from 2011–2019; German bioeconomy councils; Fraunhofer senate; BRAIN Biotech supervisory board.
Klaus Nestler
Life-science finance/M&A profile: Stifel Europe Advisory, ACXIT Capital, BioConnect AG, SBC Warburg, cross-border healthcare capital markets, venture capital and M&A.
Prof. Dr. med. Hans-Dieter Volk
Direct Charité link: former head of the Institute of Medical Immunology at Charité, founding director/speaker of the BIH Center for Regenerative Therapies, senior professor at Charité, focused on translational immunology, immune biomarkers, virus infections in immunocompromised patients, regenerative medicine, and cell/gene therapies.
ProBioGen’s own profile notes that BCRT and Charité immunology generated spin-offs including ProBioGen AG.
Prof. Dr. Ralf Wagner
Medical microbiology/virology at University of Regensburg. ProBioGen says his team is involved in vaccine research including preclinical and clinical development, and that he served in roles for public-funded vaccine clusters including EU, Gates Foundation, NIH, BMBF and research foundations. He also founded Geneart AG and later served as VP Synthetic Biology after Life Technologies acquired it.
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Management-structure change: what changed and when?
The pattern is clear:
▪️ 2024–2025: ProBioGen first brought in Alfred Merz as COO/interim CEO, then elevated him to full CEO effective April 2025.
▪️ September 2025: ProBioGen was selected to operate the GMP manufacturing unit of the Berlin Center for Gene and Cell Therapies, a Charité–BIH–Bayer project.
▪️ April 2026: ProBioGen added Simon Johannes Bulling as COO, shifting Merz into a cleaner CEO role and putting a specialist in GMP scale-up, multi-site operations and biologics manufacturing into the operational seat.
So the company moved from founder/science-driven CDMO Charité-origin story toward a more institutional structure:
▪️ CEO with Bayer/Novartis background
▪️ COO with Celonic/Recipharm/Rentschler/Vetter/Sandoz background
and a supervisory board that combines Minapharm/Africa biologics, Charité/BIH immunology, vaccine/Gates-linked cluster experience, and life-science finance.
How this aligns with the Ebola case in Berlin
The alignment is contextual and infrastructural, not evidence of direct involvement.
The current Berlin Ebola case involves U.S. missionary physician Dr. Peter Stafford, infected while treating patients in the DRC.
Reuters reports that he is being treated at Charité Berlin, with his wife and four children also admitted to an isolation ward as close contacts; the outbreak involves a rare Ebola strain and has killed more than 130 people.
The ProBioGen relevance is that, in the same Berlin–Charité ecosystem, ProBioGen has just been positioned as a major GMP manufacturing operator for advanced therapies at the BC GCT, a Charité/BIH/Bayer-linked infrastructure project.
The BC GCT project is not about Ebola treatment per se; it is about gene and cell therapies, viral vectors, GMP production, clinical material, and translational medicine.
The investigative framing would be:
Within months of ProBioGen formalizing its role as GMP operator for a Charité–BIH–Bayer advanced-therapy hub, and days after ProBioGen installed a new COO specialized in GMP scale-up and biologics manufacturing, Berlin became the European treatment site for a high-profile Ebola evacuation from the DRC.
This does not prove operational involvement by ProBioGen, but it places the company’s management restructuring inside the same Berlin biomedical-security ecosystem: Charité isolation medicine, BIH translation, Bayer-linked advanced-therapy infrastructure, viral-vector/vaccine manufacturing capability, and Africa-facing biologics networks through Minapharm.