#PathQuiz 🔬🦴 #BonePath
10-year-old boy presents with anterior tibial bowing.
A) Fibrous Dysplasia
B) Low-grade central osteosarcoma
C) Adamantinoma of long bones
D) Osteofibrous Dysplasia
#Pathology#BonePath
ALT Woven bone with prominent osteoblastic rimming surrounded by spindle-shaped cells @IARCWHO
ALT
Axial CT showing the tumor is confined to the cortex without medullary involvement @IARCWHO
#PathQuiz 🔬🦴
A) Solitary Fibrous Tumor
B) Chondromyxoid Fibroma
C) Osteoblastoma
D) Phosphaturic Mesenchymal Tumor
#Pathology#BonePath
ALT A 45-year-old female presents with severe muscle weakness, bone pain, and multiple fractures. Laboratory tests reveal profound hypophosphatemia. Spindle cell tumor with focal grungy calcification @IARCWHO
ALT An 11-year-old female presents with an expansile tibial lesion showing multiple fluid-fluid levels on MRI. Cyst wall showing lack of distinctive cell lining and composed of spindle cells with scattered giant cells and hemorrhage @IARCWHO
ALT A 22-year-old male presents with chronic pain in his proximal tibia. Imaging shows an eccentric, metaphyseal, lobulated lytic lesion with a sclerotic margin. Stellate cells embedded in a myxoid matrix are seen on the right with more cellular areas containing round cells on the left @IARCWHO
Just presented our work at #USCAP2026 on the osteofibrous dysplasia–adamantinoma spectrum, highlighting a 20-year @UTMDAnderson experience with these fascinating fibro-osseous tumors.
Grateful for the opportunity and to my mentors.
#BonePath
ALT A 30-year-old male presents with a slow-growing, painful mass in his lower leg. Imaging reveals a soap bubble osteolytic lesion in the anterior tibial cortex. Neoplastic epithelial cells forming tubular structures @IARCWHO
History of spine radiation as a child for a CNS neoplasm, few years later with a spinal bone lesion (H&E and p53 IHC).. no osteoid formation seen in the tumor, likely diagnosis? #neuropath#pedipath#molecpath#bonepath