The PCR (Polymerase Chain Reaction) test was invented by Kary Mullis for which he received the Nobel Prize in Chemistry in 1993. Unfortunately, the PCR Test for has been used in a fraudulent manner. With the PCR technique, tiny bits of DNA can be amplified, so they can be measured by conventional devices. This amplification is called the Cycle Threshold, or CT for short. The CT can be adjusted on the PCR machine from 20 to 40. A CT under 30 gives accurate test results. A CT above 30 makes the test too sensitive and gives high rate of false positives, a test that is falsely listed as positive for live virus. The CT for C0\/lD testing for was set to 40, an obvious fraudulent use of the test. The result of this high CT has been a “Casedemic” which has created "inflated fake case numbers" and needless fear in the population. Multiple peer-reviewed studies using viral culture, growing live virus in cells, found that samples with high CT values (>33–35) rarely or never yielded culturable (i.e., infectious) virus. Thus, the term "casedemic", a term describing surging "fake case" counts driven more by ultra-sensitive detection of non-infectious material than by widespread active illness. This fraud fueled public fear, lockdowns, and policy decisions. See References:
La Scola, Bernard, et al. "Viral RNA Load as Determined by Cell Culture as a Management Tool for Discharge of SARS-CoV-2 Patients from Infectious Disease Wards." European Journal of Clinical Microbiology & Infectious Diseases, vol. 39, no. 6, June 2020, pp. 1059–1061.
doi.org/10.1007/s10096-020-0… (PubMed:
pubmed.ncbi.nlm.nih.gov/3234…).
Widely cited (>1,000 times). This study of 183 positive samples found 100% culture positivity at low Ct (13–17) dropping to 0% at Ct ≥34—directly supporting that high-Ct positives frequently detect non-viable material.
Bullard, Jared, et al. "Predicting Infectious Severe Acute Respiratory Syndrome Coronavirus 2 from Diagnostic Samples." Clinical Infectious Diseases, vol. 71, no. 10, 17 Dec. 2020, pp. 2663–2666.
doi.org/10.1093/cid/ciaa638 (PMC:
pmc.ncbi.nlm.nih.gov/article…).
Widely cited (>1,500 times). Analysis of 90 positive samples showed no infectious virus recoverable above certain Ct thresholds, reinforcing the statement's point on sensitivity leading to non-infectious detections.
Singanayagam, Anika, et al. "Duration of Infectiousness and Correlation with RT-PCR Cycle Threshold Values in Cases of COVID-19, England, January to May 2020." Eurosurveillance, vol. 25, no. 32, 13 Aug. 2020.
doi.org/10.2807/1560-7917.ES… (full text:
eurosurveillance.org/content…).
Widely cited (>1,100 times). This large UK study linked high Ct values to sharply reduced culturability/infectiousness (e.g., ~8% culture-positive >Ct 35), lending evidence to the "casedemic" critique of high-Ct protocols inflating case numbers.