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May 5
Ihre Überheblichkeit können Sie sich nicht leisten, @Elke_Austenat. Bildung gibt es z. B. durch Lesen diverser Studien. Da haben Sie und andere ja nichts vorzuweisen. #Zotero aber, und ganz viele als Sammlung: #PubMed, #EuropePMC, #CochraneLibrary, #NLM... Das wäre ein Anfang.
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Excellent point. Another factor that perhaps can't be measured is that every other method on that chart has huge support (ads, docs, retail, govt., subsidies, press, and more) while vaping is mercilessly throttled and vilified. So that success is *despite* the stiffest headwind.
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They are mostly the same species in England. :-) A further nuance: "effectiveness" = "efficacy" USE If a medicine is 100% efficacious, but no one uses it, it is 0% effective. Nicotine vapes are among the most "efficacious" and BY FAR the most USED.
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This is a fascinating and important thread and discussion. Kudos. Another relevant factor: Which products proven to help people stop smoking are most appealing, most accessible, and most widely used? The answer to that question matters - a lot.
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PS I agree that "potential" is a weasel word that Tobacco Control started using in 2013 and are still using today
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Gross it up for Scotland and Wales would give 10.8m /87% = 12.4m 4.4m / 12.4 m = 35% Not all the 4.4m are long-term quitters so the long-term success rate is a bit less
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We know from the Smoking Toolkit Study how many ecig quit attempts there have been (England only) - roughly 900k pa - so 12 x 900k = 10.8m
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Worth noting that the Cochrane conclusion is not exactly spectacular - given the change in prevalence since 2012😀
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"Big hitter, the Lama." Complexity to confuse = not good Accuracy in communication = good My further point is that we need more and lots of options to help people who smoke to stop smoking--even very good options will not work for everyone. #AbundanceAgenda
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I can't resist adding more pedantry: Be very careful and cautious comparing absolute success rates (%s) across studies. Lots of factors influence those beyond the potency of an intervention. Fair point (back to @jkelovuori) that the "reach" of an intervention matters bigly!

ALT Ricky Bobby declaring "If you ain't first, you're last"

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Amazing. That is nearly 3X the success for varenicline at one year (which, if I'm not mistaken, *declines* over time). Imagine looking at a chart like that, as FDA honchos all did, and thinking "naw, not good enough." Truly infuriating.

ALT No Way Randy GIF by Zack Kantor

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But ~50% isn't unreasonable, either. Check out this brand new article from Kasza et al: Of adults who smoked in 2014-2017, 50% those who used ENDS frequently had stopped smoking at some point in the 2019-2022 period! frontiersin.org/journals/pub…
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Some of the longitudinal studies submitted in PMTAs show numbers that even exceed 50 percent success. (If I'm citing their top-notch team correctly, @jgitchell?) Makes you wonder how high that'd be w open choice of device / flavor / strength coaching.
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Just my 2 cents, but I think "most effective" is not that far off if we consider impact. "These scores suggested that e-cigarettes had by far the greatest impact on smoking cessation at the population level" jamanetwork.com/journals/jam… Not Cochrane, and only England, but still. 🙂
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"unexpressed gratitude" 😂🤣😭☠️
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