27 Oct 2025
#supramolecular helicates bind DNA junctions by induced-fit too! Exploring how helicate size, shape and symmetry affect structures of #DNAjunctions @J_A_C_S
pubs.acs.org/doi/10.1021/jac…
Congrats @SJ_Dettmer, Hugo, @SBajpaihere @HannonGroup @UoBChemistry @MIBTP_BBSRC @uob_bear
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#OpenAccess
Biochemical and mechanistic analysis of the cleavage of branched DNA by human ANKLE1
doi.org/10.1093/nar/gkad416
@UoDLifeSciences
#DNAJunctions
27 Jun 2023
Human ANKLE1 provides the final opportunity for cells to process junctions linking chromosomes so as to prevent cell division. We have analysed the mechanism of this GIY-YIG nuclease in depth. See doi.org/10.1093/nar/gkad416 @NAR_Open
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