Which extraintestinal manifestation can occur in ulcerative colitis? A. Arthritis B. Cataract only C. Hyperthyroidism D. Nephrotic syndrome

IBS overlaps with organic GI and extraintestinal diseases @LinChangMD highlights the importance to keep on the radar common causes of IBS symptoms despite remission #IBSDays2026 @ibs_days

Crohn’s disease Key extraintestinal manifestations — eyes, joints, skin, liver, and important complications Save for revision and share with your medicine colleagues. #InternalMedicine #CrohnsDisease #IBD #FCPS #MRCP

Noe et al just published a wild one 🤯 #UC in endoscopic remission but then 💥 Leukocytoclastic vasculitis #LCV pulmonary nodules?! Severe extraintestinal manifestations with a “quiet” #IBD gut 👀 Read: bit.ly/3SynLTF #PedsGI #IBD #MedTwitter #Pathology

📊 Nearly 1 in 10 IBD patients develop a new extraintestinal manifestation within 2 years of starting advanced therapy. Escalation ≠ full disease control: gastroendonews.com/a/cTkBAA/… #IBD #Crohns #UlcerativeColitis #Gastroenterology

✓ Amoebic Liver Abscess- It is Caused by Entamoeba histolytica infection, it is a common extraintestinal manifestation of amoebiasis. • Location- M/C Right lobe of liver (2-6 cm in size). ∆ C/F- Fever, right upper quadrant abdominal pain (often referred to the right shoulder), hepatomegaly, weight loss & malaise, night sweats, jaundice (rare) & diarrhea in some cases. ✓Dx- Clinical, antibody detection, USG/CT= Hypoechoic or low-density lesion with peripheral enhancement.mAspiration of abscess yields characteristic "anchovy sauce" brownish pus, typically sterile on culture. ∆ T/t- Metronidazole or other nitroimidazole drugs followed by a luminal agent to eradicate intestinal colonization.

The single most unifying diagnosis is Ulcerative Colitis (UC)—an Inflammatory Bowel Disease (IBD) presenting with classic extraintestinal manifestations (EIMs). While Crohn's disease also causes extraintestinal signs, the specific clinical triad highlighted in this illustration points heavily toward UC.

Inflammatory Bowel Disease (IBD): Conditions like Crohn's disease or ulcerative colitis cause chronic inflammation of the digestive tract, resulting in bloody diarrhea. They can also cause extraintestinal (outside the gut) symptoms like erythema nodosum (tender, painful red nodules under the skin) and mouth ulcers/abscesses. Differential diagnosis Behçet's Disease

i disagree. uveitis can be the first sign of ankylosing spondylitis or sarcoidosis, hypertensive or diabetic retinopathy reflects systemic status, and episcleritis/uveitis are extraintestinal manifestations of crohn’s. ophthalmo needs internal medicine, not a separation from it

✅ A) Crohn’s disease The image shows the classic pathological hallmarks of Crohn disease: 🔍 Key clues: • Transmural inflammation (full-thickness bowel wall involvement) • Cobblestone mucosa • Deep linear fissuring ulcers • Patchy involvement (“skip lesions”) 🧠 Why Crohn’s? Crohn disease is an inflammatory bowel disease (IBD) that can affect: 📍 Any part of the GI tract — from mouth to anus Most commonly: ➡️ Terminal ileum colon. Unlike ulcerative colitis: ❌ Crohn’s is transmural ❌ Discontinuous ❌ Often causes fistulas, strictures, and abscesses. --- ⚡ Classic Features of Crohn Disease Gross Morphology • Cobblestone appearance • Creeping fat • Thickened bowel wall • Skip lesions --- Histology • Noncaseating granulomas (not always present) --- Symptoms 🚽 Chronic diarrhea 🔥 Abdominal pain ⬇️ Weight loss 🩸 Sometimes blood in stool 🦴 Extraintestinal manifestations: • Arthritis • Uveitis • Erythema nodosum --- ❌ Why Not Ulcerative Colitis? Crohn DiseaseUlcerative Colitis TransmuralMucosal/submucosal only Skip lesionsContinuous disease Anywhere in GI tractColon only Fistulas commonToxic megacolon more classic Cobblestone mucosaPseudopolyps --- 💡 High-Yield Pearl > “Cobblestoning transmural inflammation = Crohn disease.”