🔶Arsenic poisoning.
∆ Clinical Features-:
• Acute poisoning: rice-water stools & garlic odor.
• Chronic poisoning hallmark: Raindrop pigmentation & hyperkeratosis (palms/soles).
• Nail sign: Mees' lines.
📍Cancer risk: skin (SCC, BCC), lung, bladder.
∆ Cause of death- Circulatory Collapse.
✓ Management- Antidote: Dimercaprol (BAL).
• Acute Poisoning-: Gastric lavage with freshly prepared FeSO₄ solution, Chelating agents- Dimercaprol (BAL), DMSA, DMPS, Supportive- Fluids, electrolytes, treat shock.
• Chronic poisoning- Removal of source (safe water), Keratolytics, chelation therapy.