Even for injectable, non-alkylated testosterone, elevated hepatic lipid flux (from altered FFA mobilization and reduced HDL-mediated reverse cholesterol transport) creates steatotic load: DHM's AMPK → ACC/CPT-1α axis directly offloads this

Doing the injectable slu and am really loving it. 2.5mg in the AM and 2.5 sometime after lunch, have not tried mots-c though.

#shilpamed #Shilpa Shilpa Medicare Company Q4 Con-call updates Business Verticals - Where does Shilpa plays? API — Oncology Non-Oncology Formulations (FDF) Biologics Biosimilars CDMO (API Biologics) Peptides GLP-1 (Emerging) ADC Platform (Early stage) Polymers Specialty Chemicals (Niche CDMO) Recombinant Human Albumin (Expect commercialisation from FY29) 1. FY27 Launches: Rotigotine Transdermal Patch (SMLTDP08) _ Europe: First TDS product in EU. EMA final approval received. U.S. ANDA filed in Q4FY26. Full ramp-up in FY28 after initial launch. Global market ~USD 800 mn . Ondansetron ER Injection — OERIS™ (SMLINJ011) _ India: World's first long-acting ondansetron injection. Phase 3 completed. CDSCO approval expected 1HFY27. India launch FY27; Europe Phase 3 U.S. filing to follow. Global market ~USD 375 mn. OLC — Oxylanthanum Carbonate (Unicycive CDMO) Exclusive CDMO partner. PDUFA date June 29, 2026. Dedicated commercial block commissioned. Mgmt cautious on near-term contribution; milestone income accrues on approval launch. Tadalafil Oral Disintegrating Film _ Europe Oral thin film platform product. Scheduled for Europe market in FY27. Adds to ODF capacity utilization at Bangalore facility. Abraxane — Nab-Paclitaxel (SMLINJ015) Complex liposomal albumin-bound injectable. Exhibit batches completed Q4FY26. BE studies underway. EU RoW filing targeted 1HFY27. EU market ~USD 163 mn. NorUDCA — Noduca™ (India Global) _ Lauched in Q3 FY2026: First-in-class NAFLD treatment globally. Growing on QoQ basis since Nov 2025. 6-month disease duration means data accrues through FY27. 3 marketing partners own brand. Global expansion FY27–28. Target NASH indication globally. 2. FY28 Pipeline: Enzalutamide — Xtandi (SMLOSD016) Semaglutide GLP-1 Aflibercept Biosimilar ADC Biosimilar #1 Nivolumab Pembrolizumab Biosimilars 2 NBE Programs (mAbTree Alveolus Bio) Recombinant Human Albumin Capex: 1. FY26: ₹361 cr 2. FY27: ₹300 - 380 crores in New oncology API block (capacity expansion), ADC GMP manufacturing suite (Dharwad), Peptide large-scale manufacturing block, OLC dedicated commercial block (Raichur) and Albumin Phase 3 trial batches (Kadechur) 3. FY28 Capex Outlook: Expected to moderate vs FY27 What makes FY27 particularly catalytic? is the sheer density of binary events compressed into a single year — the OLC PDUFA, Rotigotine EU launch, Aflibercept India launch, ADC GMP commissioning, and two NBE programs entering Phase 1. Any two or three of these going right simultaneously would significantly re-rate the stock.

The twice-yearly injectable PrEP drug Lenacapavir is now being administered in South Africa, thanks in part to the @GlobalFund, which (RED) supports. The shot offers nearly 100% effectiveness at preventing HIV infection and much easier adherence to treatment.

Injectable Peptides Boom Online, Regulation Lags miragenews.com/injectable-pe…

…countless citizens who are disabled&enduring avoidable medical conditions,as well as many deceased,following the Pfizer injectable&the unlawful mandates that robbed people of their right to self determination.The immune dysfunction is ongoing.Our health services can’t cope.

And the $NVO pill is SO much better than the injectable imo

Study: Uptake of long-acting injectable HIV therapy remains low among Medicare beneficiaries. Two years after the FDA approved long-acting treatment, 97% of beneficiaries still used daily oral medications. Read more: ow.ly/YNRE50Zc2S9

Long-Acting Injectable Antiretroviral Therapy in Medicare-Enrolled Adults With HIV HIVを有するメディケア加入成人における長時間作用型注射抗レトロウイルス療法 米国のメディケアPart B/Dに加入するHIVを有する成人を対象に、2021〜2023年の長時間作用型注射抗レトロウイルス療法（LA-ART）の利用を調べた横断研究。 LA-ARTの利用は2021年0.4%、2022年1.9%、2023年3.0%に増えたが、全体として低かった。 2023年には、55歳以上、米国先住民・アラスカ先住民、南部や農村部の居住者、認知症、心不全、脳卒中、慢性腎臓病などがある人で利用が少なかった。 一方、Medicaidとの二重加入者、Medicare Advantage加入者、メンタルヘルス障害がある人では利用が多かった。 費用、通院、地域格差に配慮した公平なアクセス改善が必要だ。 In 100% Medicare data from 2021-2023, long-acting injectable ART use among adults with HIV rose but remained low, reaching 3.0% in 2023. Uptake was lower among older adults, American Indian/Alaska Native beneficiaries, rural residents, Southerners, and people with some chronic conditions, pointing to equity and access gaps. #HIV #長時間作用型注射療法 #医療格差 #HIV #LongActingInjectableART #HealthEquity jamanetwork.com/journals/jam…

I'd also recommend advocating for the inclusion of a sharps container. Some people may rely on injectable medication and may not be comfortable administering it in a public bathroom, or if it's a migraine abortant would also benefit from a private space to let it kick in.

How does topical compare to injectable?

And? After the last couple years I’ve had, I think I’m allowed to get a tiny bit of lip filler, the first injectable I’ve ever gotten, at the age of 36.

“Researchers found that just 3% of Medicare beneficiaries with HIV were using the injectable treatment in 2023” cidrap.umn.edu/hivaids/uptak…

Pull or injectable slu?

URGENT WARNING: PESTICIDE POISON IN YOUR DOGS & CATS – ORAL PILLS, TOPICALS & YEAR-LONG INJECTIONS These so-called “flea and tick medications” are not medicine. They are powerful pesticides — insecticides designed to attack and destroy nervous systems. Whether given as monthly oral pills, topical spot-ons, or the new long-acting injectable shots that stay in the bloodstream for up to 12 full months, the result is the same: Your pet’s blood becomes toxic. Documented adverse events from these pesticide-based products include: • Severe neurological issues • Seizures • Tremors • And death Once the chemical is inside — swallowed, absorbed through the skin, or injected — you cannot wash it off. You cannot reverse it. All you can do is watch and hope your dog or cat survives the damage to their nervous system. Veterinarians continue to tell pet owners these products are “safe and effective.” Pet owners trust their vets and keep giving them. But we know exactly what happens when Big Pharma loudly claims something is “safe and effective.” This is not protection. This is chemical Russian roulette with your best friend’s life. Protect your dogs and cats. Stop the pesticides. Share this before another pet suffers seizures, neurological collapse, or worse. 🐾 Your animals deserve better than poison in their veins.

$NVO has officially launched Wegovy in Chile. The launch event gathered more than 1,500 healthcare professionals and industry representatives, highlighting growing interest in obesity treatment. Novo emphasized that obesity is a chronic disease requiring long-term management rather than simply a lifestyle issue. Clinical data presented showed that about one-third of patients achieved up to 25% weight loss, with roughly 84% of the weight lost coming from fat mass. Wegovy is now available in Chile in five weekly injectable dose strengths, while approval of the higher 7.2 mg dose is also expected. Link to article: portalmetropolitano.cl/wegov… #stocks #Investing

I'd just like to point out.... to whoever is listning.... ---here are warning labels for covid-19 and a corresponding injectable products !! -- how evil does one have to be, to inject this type of product into a baby ? 💉

im still on 25 mg of stupid pills because my monthly injectable doesn't work well enough on its own 💀 id rather take 4 pills a day that genuinely lower my iq than deal with these fucking migraines anymore

Japan's Eisai to pump $64m into UK plant to package injectable drugs s.nikkei.com/4eoKSaJ

🗣️ New viewpoint in @JAMA_current led by @PiatkowskiTim! 💉 Illicit injectable peptides are increasingly promoted online for enhancement, raising concerns about youth exposure, limited safety evidence, and regulatory gaps. 🔗 Read here: tinyurl.com/jamapeptides