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Detailed analysis of pathogenesis of transformed CTCL - awful disease. Oncogenic reprog to: • oxphos metabm • cellular plasticity • ⬆️ myc & E2F • ⬇️ MHC-I Myc / Oxphos perturbation pharmacologically v potent anti-tumour activity. Song et al. #lymsm aacrjournals.org/cancerdisco…