Life Extension doesn’t add flavorants to their Super Omega capsules. I’ve seen their independent analyses for purity and rancidity. They maintain a database for every single batch. I was surprised by how good the reports looked. I’ve been taking them for years too.

I expected this, but I found Bill Harris (OmegaQuant founder) very unimpressive in the interview. It's just astonishing how bad "the science" is, and how uninformed The Experts are. You'd think The Omega Guy would know about o6 oxidation products, or think about them. Instead, a lot of talk about "associated risk factors." To my engineer ears, these mainstream "scientists" sound like a tribe doing a rain dance: if you appease the Risk Factor Gods enough, you won't get heart disease. They don't even conceive of the idea of understanding a mechanism or causal relationship. Imagine that I recommend you paint bridges red cause the Golden Gate is red and it hasn't fallen over. Red paint is "associated" with good bridge outcomes. These people have no equivalent of engineering knowledge for heart disease (or much else), it's all rain dance for them.

As I was listening, I thought "This is just some dude w/ a centrifuge selling blood spot tests for $100 a pop. How hard could it be?" Since you're sort of a lab guy yourself, how hard would it be to make your own OmegaQuant and put it out commercially? It's not regulated I assume, cost is probably trivial @ scale.. most of all I'd love to change WHAT is tested besides saving cost & therefore making it more accessible (I've spent over $3k on OmegaQuants) 1. Mead acid would be great 2. If anything I'd like to REMOVE the red blood cell phospholipids, if at all possible, since I want a proxy for adipose tissue composition 3. Total amounts for each fat, not just composition%. E.g. I'd expect high total o6 with same o6% to be much worse, and I'd expect that you can't out-balance a high o6 diet with high o3 at some point.

*Mass spec looks like a field of tall grass.* "It's peak 22 bro."

Only use an oil as a TG or rTG to optimize blood EPA and DHA levels (Parasol, Nordic Naturals, Carlson). Get levels tested by OmegaQuant and get your levels to 8-12% to significantly reduce primary MI and SCD and lower CHD by over 30%.

@exfatloss My @OmegaQuant came in. For 3 years I eat virtually little fish beyond cod. 3 years ago i had a sardine phase. I eat very low PUFA across the board. Skinless chicken. Lots of beef. Dairy (on pause now), Cod. Nourish Food Club/ Angel Acres low pufa eggs. Primarily coconut oil and MCT oil in cooking for the past 1.5 years. I was SAD 1981 - 2019. 2019 was high n6 keto. 2020-2021 was "plant based". 2022 saw more meat. 2023 had periods of carnivore. mid 2024 saw the transition to more carbs (fruit, rice) while being Low A. 2025 was more "Peaty". Seed oils came out of my diet by end of 2022. Low PUFA (from whole foods) by mid-end of 2023.

Will do, will be interesting to see how the longer list of comprehensive fatty acids compares to what showed up on the blood draw for my previous serum OmegaQuant

holy (PUFA) shitballs. contrast with my buddy @gatordadsteve who I believe has literally the best OmegaQuant results ever recorded.

I think the effect of vE on LA is very limited and can even make it worse, @TuckerGoodrich has talked about this. I don't think charcoal would help against LA, but I might be wrong. Bad effects from avoiding PUFAs... it seems extremely hard to do, so I'm skeptical of anecdotes. Brown in a study tried eating a lab-created zero-fat diet and he did not manage to induce ANY symptoms of EFAD. There is a small handful of anecdotes, but they involve "being shot in the gut and fed through a tube for months at a time" and similar crazy scenarios. It is possible to get EFAD, apparently, but it's very difficult in practice. Anyone who grew up on the SAD will have literally decades worth of linoleic acid in their adipose tissue. I don't believe any EFAD symptoms until you show me an OmegaQuant Complete where you beat that 8-year fruitarian whose test I have.

Nice, that sort of "reverse ratchet" is pretty much what Modern PUFA Theory hypotheses should happen. You don't need to do keto, have you tried the potato diet or rice diet style HCLF protocols? Should help deplete your PUFA just as well and gives you some variety. Re yoyo/GLP-1: yes and no. For one, I do not like these drugs or their side effects. Plus, if they work, we don't know WHY they worked. That said if you were to try that with before/after OmegaQuant Complete tests, I'd be curious. I'm just not the one who's going to try.

It's not 100% well established, but probably 4-8 years. We don't have evidence of 1 person starting high, doing a strategy of depleting it, and then going all the way down. We DO have evidence of people who did many years (5 typically, often a decade) of an extremely strict diet for other reasons, who test extremely low on the OmegaQuant Complete. So we technically don't know if those people were ever high, or that we who are emulating them will get all the way down. But we're about 3-5 years into a few dozen people trying it, so hopefully we'll have the answers in a few more years. I'm personally about 3 years in.

So how long does it actually take to deplete PUFA, such that it won't be replenished after a singular meal? As per omegaquant or similar Or has no one done that level of testing

I wish Peaters would try & test this stuff more :) Many of us Pufa pilled people have been trying this for years and it seems to take 4 years. Serum goes super quick, do a zero fat diet and it'll drop your serum LA within 3 days. I've done it many times. The trick is, if you go back on a regular/high fat diet, does it come back up? Highly likely yes, cause you didn't deplete much in 30 days, you only masked it within the first 3 days. Serum is not a perfect proxy for adipose for example, it highly depends on your dietary context. You can test with an OmegaQuant Complete. Unfortunately, almost no Peater seems interested in actually testing that ha.

I've been low n6 for 3 years. Been lower fat and higher carb for 1. Dialed it up for the past 6 months too. I'll be interested to see what my OmegaQuant says (just ordered)

Haven't had a seed oil in 6 years. I dont eat pork, eggs, and only eat chicken tenderloin like once a month. My LA was in the 7s. I have increased my fats since this test in March so curious how the next looks. I do eat alot of seafood so my O3 is thru rhe roof.

Your blood-brain barrier is elite

Indeed

@gatordadsteve did 1.1:1 recently btw I loved you in that show