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💤 🫀 🫁 🧠 👁️ 💪 🫘 Today marks a meaningful milestone for LABS — our SleepChart paper, “Sleep chart of biological ageing clocks in middle and late life,” is now online in @Nature. In this work, we link sleep patterns with biological aging clocks across the brain and body, highlighting how sleep may reflect broader systemic aging processes. Key takeaways: 🧠 Sleep and biological aging clocks show a coordinated brain–body U-shaped pattern; this relationship extends beyond the brain alone and involves multiple organ systems and at multiple omics layers. 🧬 Sleep disturbances are linked to disease risks and shared genetic architecture: Short sleep appears to have a broader systemic impact, while long sleep shows a more focal, brain-enriched disease burden. 💤 Late-life depression provides an important example. Brain and adipose aging clocks mediate the relationship between long sleep and late-life depression, while short sleep appears to exert a more direct effect. As always, inverse causation cannot be fully excluded (potentially a sleep-LLD bi-directional relationship). We are excited to share both the paper and the interactive SleepChart portal with the community (including GWAS summary statistics, etc.). Paper: nature.com/articles/s41586-0… SleepChart portal: labs-laboratory.com/sleepcha… Great collaboration from our partners: @chrisdav66 at the University of Pennsylvania, @AndrewZalesky from the University of Melbourne, #PaulAisen and #MichaelRafii from the University of Southern California, #LuigiFerrucci, #KeenanWalker, and others from the @NIHAging, and many other collaborators! nature.com/articles/s41586-0… #SleepResearch #BiologicalAging #AgingClocks #Neuroscience #PrecisionHealth #BrainHealth #AIinMedicine #LABS
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Is your child’s bedtime too late? In the run-up to school next week, here’s a guide to when your child should be going to bed - and some tips from schools on how to achieve it schoolscompared.com/guides/i… #childsleep #sleepschedule #backtoschool #sleepchart #childsleeptips

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30 Aug 2018
głupoty jakie ja i inni nauczyciele mówili na lekcjach do tej pory „look at the sleepchart?” [flipchart] „this task is task-consuming” [time-consuming] 📝😋 „is it okay? okay okay” „i like frightened eggs” [fried] 😱🍳 „- what does swear mean? - swear? for example holy shit”
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Only 6 months left on my #Sonyxperia can't wait. Worse phone I've ever had #EE #SleepChart
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So I have an awesome moleskine in use as a journal/sketchpad/sleepchart/lots of random stuff like lyrics and chords and hollow reflections
Did your children get enough sleep last night? Did you? #kidsfirst #sleepchart #sweetdreams @ Kids… instagram.com/p/7acZUUg-uM/

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