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🚨El investigador Pioletti y su equipo de la empresa flowbone desarrollaron un hidrogel inyectable. Que tiene el propósito de aumentar rápidamente y de forma localizada la densidad ósea. En colaboración con Vincent Stadelmann de la Schulthess Klinik de Zúrich, presentaron una novedosa terapia.
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🔴El investigador Pioletti y su equipo de la empresa flowbone desarrollaron un hidrogel inyectable. Que tiene el propósito de aumentar rápidamente y de forma localizada la densidad ósea. En colaboración con Vincent Stadelmann de la Schulthess Klinik de Zúrich, presentaron una novedosa terapia.
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وداعاً لهشاشة العظام.. ابتكار هيدروجيل خارق يغير قواعد اللعبة، علماء من سويسرا (EPFL) وشركة Flowbone يطورون مادة جيل تُحقن داخل العظام لتقويتها بسرعة خيالية. 💉🦴👇🏻 🔹 نتائج مرعبة: تزداد كثافة العظام بمقدار 5 أضعاف خلال أسابيع فقط. 🔹 درع داخلي: المادة تحاكي المعادن الطبيعية للعظام وترمم المناطق الهشة فوراً. 🔹 حماية قصوى: عند دمجها مع الأدوية التقليدية، توفر دفاعاً لا يقهر ضد الكسور القاتلة. هذا الابتكار ليس مجرد دواء، بل هو ترميم فوري يعيد الأمل لملايين المصابين بهشاشة العظام حول العالم.
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Scientists created a hydrogel that strengthens bones in weeks — bone density increased by 5X in a trials. Researchers at EPFL and the startup Flowbone have developed a revolutionary injectable hydrogel designed to treat osteoporosis with unprecedented speed. Made from a sophisticated blend of hyaluronic acid and hydroxyapatite nanoparticles, this material mimics the natural mineral composition of human bone to reinforce fragile areas from the inside out. In laboratory trials, the treatment increased bone density in subjects threefold within weeks. When paired with the existing osteoporosis medication Zoledronate, density at the injection site surged by nearly five times, offering a potent localized defense against fractures. This breakthrough addresses a critical gap in osteoporosis management, a condition that affects millions of people worldwide and often leads to life-threatening injuries. Unlike traditional therapies that can take significant time to show measurable results, this hydrogel provides immediate structural support while accelerating the body’s natural strengthening processes. As the research team moves toward clinical trials and regulatory approval, this technology promises to redefine recovery, offering patients a faster and more effective shield against the debilitating effects of bone loss. source: EPFL & Flowbone Research Group. (2024). A biomimetic injectable hydrogel for local bone reinforcement in osteoporosis. Bone Journal.
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Medical researchers have successfully engineered a localized, flowable matrix designed to rapidly restore structural integrity in fragile skeletal areas. This innovative approach by the Flowbone team specifically targets microscopic weaknesses before they lead to catastrophic fractures. Millions of aging individuals globally suffer from severe skeletal deterioration, making this breakthrough a massive leap forward for preventative orthopedic care. By collaborating with clinical experts in Zurich, scientists have proven that combining this localized substance with traditional systemic medications yields extraordinary regenerative results. The specialized matrix functions by creating a supportive scaffold directly inside the weakened tissue, actively encouraging the body's natural cellular repair processes. This highly targeted application allows physicians to proactively reinforce specific high-risk zones, such as the hips and lower spine, which are typically vulnerable to sudden trauma. Recently detailed in leading peer-reviewed journals, these clinical findings represent a significant shift away from relying solely on oral prescriptions that often take years to show measurable effects. This minimally invasive procedure could eventually become a routine, same-day preventative measure for high-risk demographics. As the global population continues to age, the demand for fast-acting and highly effective structural therapies has never been more urgent. This pioneering research offers a tangible, biological solution to help aging individuals maintain their physical independence and overall quality of life. Do you think minimally invasive injections will eventually replace daily medications for treating age-related bone loss?
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Medical researchers have successfully engineered a localized, flowable matrix designed to rapidly restore structural integrity in fragile skeletal areas. This innovative approach by the Flowbone team specifically targets microscopic weaknesses before they lead to catastrophic fractures. Millions of aging individuals globally suffer from severe skeletal deterioration, making this breakthrough a massive leap forward for preventative orthopedic care. By collaborating with clinical experts in Zurich, scientists have proven that combining this localized substance with traditional systemic medications yields extraordinary regenerative results. The specialized matrix functions by creating a supportive scaffold directly inside the weakened tissue, actively encouraging the body's natural cellular repair processes. This highly targeted application allows physicians to proactively reinforce specific high-risk zones, such as the hips and lower spine, which are typically vulnerable to sudden trauma. Recently detailed in leading peer-reviewed journals, these clinical findings represent a significant shift away from relying solely on oral prescriptions that often take years to show measurable effects. This minimally invasive procedure could eventually become a routine, same-day preventative measure for high-risk demographics. As the global population continues to age, the demand for fast-acting and highly effective structural therapies has never been more urgent. This pioneering research offers a tangible, biological solution to help aging individuals maintain their physical independence and overall quality of life. Do you think minimally invasive injections will eventually replace daily medications for treating age-related bone loss?
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💥El investigador Pioletti y su equipo de la empresa flowbone desarrollaron un hidrogel inyectable. Que tiene el propósito de aumentar rápidamente y de forma localizada la densidad ósea. En colaboración con Vincent Stadelmann de la Schulthess Klinik de Zúrich, presentaron una novedosa terapia. La cual combina inyecciones de hidrogel con fármacos sistémicos tradicionales. Y los resultados se publicaron en la revista Bone
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🔥 Hot Swiss Startups to Watch in 2026 – Medtech Which Swiss Medtech startups should you keep an eye on this year? Switzerland’s Medtech ecosystem continues to drive innovation in diagnostics, medical devices, and digital health. Based on last year’s rankings, these companies stand out as Swiss Medtech startups to keep an eye on throughout 2026: 🔹 Nanoflex Robotics 🔹 @Adiposs1 🔹 Testmate Health 🔹 Avelo 🔹 Neurosoft Bioelectronics 🔹 Clee Medical 🔹 PeriVision 🔹 Scanvio Medical 🔹 IMAI MedTech 🔹 Herosupport SA 🔹 biped AI 🔹 flowbone These startups were identified among the top Engineering companies in the Top100 Swiss Startup Award 2025, where a panel of 100 leading investors and industry experts ranked the most promising startups in the country. 📖 Discover the Engineering startups and all other startups in the Top100 Swiss Startup Magazine 2025: top100startups.swiss/about 📰 We regularly share news and updates about Swiss startups, including many of these ventures, in the Venturelab newsletter. Subscribe to stay in the loop: venturelab.swiss/news #TOP100SSU #SwissStartups #Innovation #Entrepreneurship #StartupEcosystem #Medtech
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El investigador Pioletti y su equipo de la empresa flowbone desarrollaron un hidrogel inyectable. Que tiene el propósito de aumentar rápidamente y de forma localizada la densidad ósea. En colaboración con Vincent Stadelmann de la Schulthess Klinik de Zúrich, presentaron una novedosa terapia. La cual combina inyecciones de hidrogel con fármacos sistémicos tradicionales. Y los resultados se publicaron en la revista Bone, donde se detalla que los ratones mostraron un aumento de 4 a 5 veces en la densidad ósea en las patas de las ratas que presentaban pérdida ósea.
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CIENCIA Y SALUD Investigadores, incluyendo al equipo de Pioletti en Flowbone, han desarrollado un hidrogel inyectable de ácido hialurónico y nanopartículas de hidroxiapatita que aumenta la densidad ósea localizada hasta 4.8 veces en solo 2-4 semanas. Diseñado para combatir la osteoporosis y reducir fracturas, combina la liberación local de fármacos
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Un equipo de científicos de la Escuela Politécnica Federal de Lausana (EPFL), liderado por Dominique Pioletti combinaron fármacos sistémicos para la osteoporosis con inyecciones de hidrogel en ratas. Lo que demostró una posible nueva esperanza para manejar el padecimiento. El investigador Pioletti y su equipo de la empresa flowbone desarrollaron un hidrogel inyectable. Que tiene el propósito de aumentar rápidamente y de forma localizada la densidad ósea. En colaboración con Vincent Stadelmann de la Schulthess Klinik de Zúrich, presentaron una novedosa terapia.
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El investigador Pioletti y su equipo de la empresa flowbone desarrollaron un hidrogel inyectable. Que tiene el propósito de aumentar rápidamente y de forma localizada la densidad ósea. En colaboración con Vincent Stadelmann de la Schulthess Klinik de Zúrich, presentaron una novedosa terapia. La cual combina inyecciones de hidrogel con fármacos sistémicos tradicionales. Y los resultados se publicaron en la revista Bone
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El investigador Pioletti y su equipo de la empresa flowbone desarrollaron un hidrogel inyectable. Que tiene el propósito de aumentar rápidamente y de forma localizada la densidad ósea. En colaboración con Vincent Stadelmann de la Schulthess Klinik de Zúrich, presentaron una novedosa terapia. El hidrogel desarrollado está compuesto de ácido hialurónico y nanopartículas de hidroxiapatita. Además del hidrogel mezclado con el fármaco anticatabólico zoledronato. Y en el lugar de la inyección, la densidad ósea aumentó hasta 4,8 veces en tan solo 2 a 4 semanas.🤯👇🏼
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🚨🗞 El investigador Pioletti y su equipo de la empresa flowbone desarrollaron un hidrogel inyectable. Que tiene el propósito de aumentar rápidamente y de forma localizada la densidad ósea. En colaboración con Vincent Stadelmann de la Schulthess Klinik de Zúrich, presentaron una novedosa terapia. La cual combina inyecciones de hidrogel con fármacos sistémicos tradicionales. Y los resultados se publicaron en la revista Bone, donde se detalla que los ratones mostraron un aumento de 4 a 5 veces en la densidad ósea en las patas de las ratas que presentaban pérdida ósea.
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Un equipo de científicos de la Escuela Politécnica Federal de Lausana (EPFL), liderado por Dominique Pioletti combinaron fármacos sistémicos para la osteoporosis con inyecciones de hidrogel en ratas. Lo que demostró una posible nueva esperanza para manejar el padecimiento. El investigador Pioletti y su equipo de la empresa flowbone desarrollaron un hidrogel inyectable. Que tiene el propósito de aumentar rápidamente y de forma localizada la densidad ósea. En colaboración con Vincent Stadelmann de la Schulthess Klinik de Zúrich, presentaron una novedosa terapia
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Proud to announce the most promising Swiss Medtech Startups of 2025, picked by a panel of 100 leading investors and industry experts 🔬 top100startups.swiss/The-12-… Discover the 12 Medtech Startups that impressed the Top100 Swiss Startup Award Jury in 2025: 🔹 @NanoflexAI, #10 🔹 @Adiposs1, #21 🔹 Testmate Health, #27 🔹 Avelo, #41 🔹 @NeurosoftBio, #55 🔹 Clee Medical, #56 🔹 PeriVision, #69 🔹 Scanvio Medical, #83 🔹 IMAI MedTech, #85 🔹 HeroSupport, #90 🔹 biped robotics, #95 🔹 flowbone, #97 Discover the Medtech Startups and all other startups in the Top100 Swiss Startup Magazine 2025: top100startups.swiss/publica… 🔗 #TOP100SSU #SwissStartups #Innovation #Medtech #StartupEcosystem
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The hydrogel shown in the image and described in the post was created by researchers led by Dominique Pioletti at EPFL (École Polytechnique Fédérale de Lausanne) and their start-up, flowbone. Their injectable hydrogel has demonstrated a rapid and significant local increase in bone density—up to about 4.8 times—in animal studies, especially when combined with systemic osteoporosis drugs, and they are now aiming to move forward with clinical studies in humans.
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Scientists at EPFL and their startup Flowbone have developed an injectable hydrogel that rapidly boosts local bone density by up to about 5 times in preclinical trials with rats—especially when used together with standard osteoporosis drugs like Zoledronate. The hydrogel, made from hyaluronic acid and hydroxyapatite nanoparticles, works within just a few weeks, but so far this dramatic effect has only been seen in animals; human clinical trials are still awaiting regulatory approval, so it isn’t available as a treatment for people yet.
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The hydrogel mentioned in the image is an injectable material developed by researchers at EPFL and the start-up flowbone, designed to rapidly increase local bone density—in preclinical (animal) studies, it achieved up to a 5x boost when combined with standard osteoporosis drugs, working within weeks. However, this treatment has not yet been approved for clinical use in humans—it’s currently awaiting regulatory approval to begin human trials, so it’s not available in medical practice yet and its effects in people have not been fully established.
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Yes, this is a real scientific development, though it’s still in the experimental stage and not yet available for widespread clinical use. Researchers at EPFL and their start-up flowbone created an injectable hydrogel made from hyaluronic acid and hydroxyapatite nanoparticles, which *mimics natural bone minerals and rapidly increases bone density*—up to nearly fivefold—in animal studies when combined with existing osteoporosis drugs, with effects appearing in just a few weeks. This breakthrough has only been demonstrated in rats so far, and human trials are still pending regulatory approval, so it isn’t a standard medical treatment yet but could lead to faster, localized bone-strengthening therapies in the future.
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