Nene doodledump!!!! #fridaynightfunkin #FNF #Nene #picosschool #pico #pitstop2 #Doodles

🚀From Bench to Paper | Efficient amyloid-β degradation in Alzheimer’s disease using #SPYTACs Alzheimer’s disease (AD) therapy faces a key challenge: clearing pathogenic proteins efficiently while minimizing side effects. A recent study reports SPYTACs (synthetic peptide-programmed lysosome-targeting chimeras), a fully synthetic, modular #eTPD platform that leverages LRP1-mediated endocytosis and transcytosis to cross the Blood-Brain Barrier (#BBB) and drive lysosomal degradation of extracellular Aβ. In 5×FAD mice, SPYTACs reduced both peripheral and brain Aβ burden, targeted existing plaques, and improved cognitive function—with fewer inflammation and microhemorrhage risks compared to antibody-based therapies. With high modularity, SPYTACs can be adapted to target other disease proteins (e.g., #Tau, PD-L1), offering a scalable and programmable strategy for neurodegeneration and beyond. Read more: cell.com/cell/fulltext/S0092… This study was supported by a range of high-quality reagents from MedChemExpress, including: #Lecanemab, #BafilomycinA1, #Chloroquine, #Pitstop2, DC-LC3in-D5, as well as multiple antibodies and recombinant proteins. medchemexpress.com/ #AlzheimersDisease #Neurodegeneration #TargetedProteinDegradation #DrugDiscovery #CNS #TranslationalResearch #Biotech

(wow 2 likes already) btw huh, unrelated but on topic. #fnf South part of my Pitstop2 marathon. #youtube

Pitstop II - Featured in our book - Commodore 64: a visual compendium Discover the vast library of games that made the Commodore 64 the most popular home computer of the 1980s! Reprints coming soon 📚 Get a stock alert: bitmapbooks.com/collections/… #bitmapbooks #book #retrogaming #c64 #commodore #gaming #f1 #formula1 #pitstop2

Pit stop 2 at Drumoak with @Abdn_Cyrenians 🤩 Make sure to stop by and say hello!  #PitStopPatter #PitStop2

🚨 NEW FRIDAY NIGHT FUNKIN' VIDEO OUT NOW!!🚨 Playing all the new Pico mixes C: #fridaynightfunkin #fnf #gaming #pitstop2 @FNF_Developers ➤ Link to video: youtu.be/msDtLqvGG38

Here's a wip of some legendary dudes. This was supposed to be a gift for them working on base game! :3 @bbpnz213 @3rdFunni342 @DegoDraws #fnf #pitstop2 #fanart

両手に花 #fridaynightfunkin #pitstop2

#fnf #pitstop2 #fridaynightfunkin #picosschool #pico #otis

#fridaynightfunkin #pitstop2 いやもうめっちゃ楽しいです！ 曲もアレンジや曲の盛り上がりも良い otis君が来るとは思わなかった〜

FRIDAY NIGHT FUNKIN' #FNF #pitstop2 #fridaynightfunkinfanart

messy asf #picosschool #picoscousin #FNF #pitstop2

x.com/Blue_0_9/status/190787… #fridaynightfunkin #pitstop2

I love stress pico mix #fridaynightfunkin #pitstop2

🇲🇽: La gente de verdad odia Darnell Erect, porque??? Esta buena la canción 🇺🇲: People really hate Darnell Erect, why??? Is a nice song #FNF #fridaynightfunkin #pitstop2

Who the fuck is this knockoff!? #pitstop2 #fridaynightfunkin

" y'did good, runt. " #picosschool #picoscousin #otis #pico #nene #pitstop2