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Fab work from @KBGinsburg et al how unbiased prognostic tools change clinical decisions @PredictProstate 👉🏽How Do Urologists Interpret Risk? Diff in Appropriateness of Active Surveillance - Clinical vs Probability-Based Risk Assessments | Urology Practice auajournals.org/doi/10.1097/…
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1 Jun 2025
Incorporating the @NICEComms Cambridge Prognostic Groups and @PredictProstate into a structured informed-decision making clinic reduces over-treatment rates of early prostate cancer bjui-journals.onlinelibrary.… via @VincentGnanapr3 et al
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Visits to @PredictProstate have suddenly surged in lat 2 days ! Biden Diagnosis effect? A reminder @PredictProstate is not for metastatic or aggressive cancers but only where treatment and surveillance are equal options
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Male >75y, PSA 2 , LUTS, DRE (urologist) firm so MRI - Bx GG1, CPG1-@PredictProstate survival gain from Tx 1% - take home 1. We need to stop doing DRE 2. MRI risks becoming the new PSA for lead time bias if we don’t use to judiciously
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Nice to see the 2025 EAU prostate cancer guidelines continue to recognise the superiority of the cambridgeprognosticgroup.com for prognosis and the @PredictProstate tool for decision making EAU biochem relapse risk groups (finally) dividing intermediate risk disease!
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That context is different and prostate cancer is v different - happy to iterate by email rather than Twitter/ if interested DM and we can discuss further
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That is exactly what the decision-support tool I posted a link to does. Probabilities derived from evidence & personalised health state valuations (with default options). It was possible over 20 years ago. Nobody has shown the much interest in developing the idea since then.
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Replying to @jimhumd @ONS
Work out life expectancy and therapeutic benefit gain in PCM va ACM Jim - at 83 this man’s LE is < 10 yrs - we would never suggest RRP in 83 yr old and would use @PredictProstate - if he was CPG4-5 EBRT much less risk of side effects as per protect
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Just seen this interesting paper - pts want to know about life expectancy & competing risk when newly diagnosed - exactly what @PredictProstate is for.. Patient Preferences for Communication of Life Expectancy in Prostate Cancer Tx Consultations jamanetwork.com/journals/jam…

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Endorsed and adopted by @NICEComms and in @Uroweb CaP guidance 2024- @PredictProstate used >6000 a month globally from >100 countries - clinicians know about it but some choose to ignore it as outputs don’t fit their thinking - all welcome to check the evidence on its veracity
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👏🏾👏🏾👏🏾@NHSEngland include work to promote use of Cambridge Prognostics Groups nice.org.uk/guidance/ng131/c… and @PredictProstate in trusts to refine & individualise management of newly diagnosed prostate cancer in their 2024/2025 Faster Diagnosis Priority workplan
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Great to see Cambridge Prognostic Groups and @PredictProstate mentioned in this latest version !
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Great to see @Uroweb EAU 2024 updated Prostate Cancer guidelines now include the @NICEComms Cambridge Prognostic Groups for prognostic stratification and point to @PredictProstate for decision making in AS vs radical treatment @NPCA_uk @david_thurtle @NHSEngland
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This is what @PredictProstate says. Show it to the patient and let them make a decision. Best aid in decision-making. Personally prefer AS. bjui-journals.onlinelibrary.…
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👀 for radiotherapy cohort - work in progress😊@UniversityCamb
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