Hyperchloremia, an increase in the serum chloride concentration above the normal range, has multiple causes. This #ASNCJASN "How I Treat" series details case studies for treatment from each major cause. kidney.pub/CJASN0806

Immune system one pager (Source unknown) h/t @OGdukeneurosurg #MedX

Comparison of methods for determining fluid responsiveness & tolerance onepagericu.com/fluid-respon…

Using DDAVP in correction of hyponatremia from @NephroMD #Nephpearls #KidneyWk 📌 Proactive strategy 📌 Reactive strategy 📌 Rescue strategy 👉 pubmed.ncbi.nlm.nih.gov/3686… 👉 pubmed.ncbi.nlm.nih.gov/2906…

Does collecting research papers feel like making progress to you? It's called the collector's fallacy and in academia, the result is often burnout or overwhelm. The solution is what I call the detective mindset: 👇 We tend to collect useful things, it is satisfactory to accumulate. We think we get a (future) benefit from each new paper added to our reference manager. 1. The collector mindset “I need to identify every paper there is and then start reading and searching for answers in the literature.” Quite often it comes from a fear of missing out on some crucial information – the desire to be "on the safe side". But the result is the exact opposite! You end up with 100 papers and don't know where to start or what is important! You end up paralyzed. 2. The detective mindset: “I just start reading and identify the relevant literature as I go, while collecting clues and creating a narrative on the fly.” The detective mindset is a little bit like solving a jigsaw puzzle. You do it step by step and it is quite satisfying to see the big picture emerge. 3. Collect the "intent to collect" Rather than adding a paper to your library create a reading list and explain exactly why you want to read the paper. Instead of the paper you collect the intent and the context. Having this little comment allows you to prioritize later on what you read or discard papers that aren't relevant anymore. I call it my "Reading Wishlist". Here is how it looks in my library - it is just a text note: 4. Pick one paper at a time - grow your reading list Get started on virtually any paper. Each will lead you to a few more papers that you find relevant. Keep an eye out for statements like this one: "Opinions regarding... fall into three camps." This is what really advances your critical thinking - we immediately know what the entire field thinks about the topic and we get 3 new papers to read, for these 3 camps. For each, the paper gives us a clear reason why we should read it i.e. to understand the position of the respective camps. 5. Clear your reading list After a while, your reading list becomes very large and here my advice is: Be ruthless. If you have not read the paper chances are you never will. Your reading list is a wish list, not a to-do list! It is meant to be fleeting. Your dreams, desires, and focus are allowed to change! 6. Tag the reading list If after deleting you still have too many entries start tagging them. Each tag corresponds to one project you are working on. I use an Obsidian plugin called Tasks. It allows me to write a small query that aggregates all tasks containing a certain tag into one dynamic list. This list has now only 7 entries and is far less threatening! 7. Tools for Discovery The detective mindset is all about reading the right papers and choosing them wisely. You ask a question or set a goal and then keep finding relevant literature that helps answer your question. I will link a few useful tools in the comment. If you want to learn my entire workflow, I have a Literature Review course for you - it consists of two chapters on managing a lit review as a collector and as a detective. You will find all of the ideas above explained in great detail with many examples.

Membranous nephropathy is ever-changing! @SethiRenalPath @GlomCon 🧫Discovery of antigen 2009- PLA2R 2014- THSD7A 🔬With microdissection and mass spectrometry: EXT1/2 - Lupus NELL1 - Many faces Sema3b - paediatric PCDH7 - autoimmune FAT1 - HSCT NDNF - syphilis PCSK6 - NSAIDS

🆕Review on: Selective glomerular hypofiltration syndrome doi.org/10.1093/ndt/gfad145 📸Schematic representation of the sequence of events potentially involved in the origin and the consequences of the selective glomerular hypofiltration syndrome

Dapagliflozin prevents Anemia in Patients with Chronic Kidney Disease | NEJM Evidence evidence.nejm.org/doi/full/1… @Stenodiabetes @gchertow @HeerspinkHiddo

1a) Welcome to a 🆕#accredited #tweetorial with 🆓CE/#CME from @cardiomet_ce, your only source for ongoing #MedEd delivered wholly on Twitter! We welcome back our distinguished expert author, #nephrologist Edgar V. Lerma 🇵🇭 @edgarvlermamd #FOAMed #cardiotwitter @MedTweetorials

Reading research papers can be challenging, especially for those with learning disabilities like dyslexia. What if you could listen to research papers instead? Introducing Audemic, the app that lets you do just that. Here's how to use it:

KDIGO is pleased to announce the publication of the Home Dialysis Controversies Conference Report in the May 2023 issue of @Kidney_Int. The conference was co-chaired by @PD_Perls and @wilkiemart. Read the news release: kdigo.co/Home-Dialysis-Confe… Download the conference report: kdigo.co/Home-Dialysis-Contr…

One of the most boring and time-consuming tasks for academics: replying to emails everyday. You can get ChatGPT to write your emails and save countless hours. Here's how to do it:

Do you spend hours formatting your citations and references manually? You can automate them with an app called Zotero. Best part: it's FREE! Here's how to do it:

Pathophysiology of #Cardiorenal syndromes 1 - 5 #MedTwitter #Nephpearls #POCUS From 🔗 onlinelibrary.wiley.com/doi/… Type 1 👇 rest of them in the thread 🧵 below

How to measure Blood Pressure (BP) at home #Nephpearls #HTNSecrets 👉 targetbp.org/tools_downloads… 👉 elsevier.com/books/hypertens…

A review of supportive care for older people with advanced CKD 🔓bit.ly/3K4XbKa Rather than focusing on disease-specific therapies, SC is a collection of adjuvant interventions & adaptations to conventional treatments that can be used to improve the individual’s QoL

With all due respect to fancy new MRAs, ARNIs, even SGLT2i's, thiazide (-like) diuretics are the absolute outcome GOATs. Imaging how much gain in QALYs these drugs have given our patients for decades now? It boggles the mind to contemplate! Pictured: SHEP, ALLHAT, HYVET, SPRINT

Sepsis associated AKI: Consensus paper ca. 2023 from @NatRevNeph @ForniLuiG #Nephpearls #AKIinICU 👉🏼 nature.com/articles/s41581-0…

Delta ratio= (change in anion gap)/(change in bicarbonate) #Nephpearls < 0.4: Normal AG acidosis 0.4-0.8: Mixed high ➕ normal AG acidosis 0.8-2.0: Pure high AG acidosis > 2.0: High AG acidosis ➕ pre-existing metabolic alkalosis 👉🏼 journals.lww.com/jasn/pages/…

Primary Aldosteronism: Diagnostic algorithm 1⃣ Screening 2⃣ Confirmation 3⃣ Subtype Classification #Nephpearls #HTNSecrets 👉 elsevier.com/books/hypertens…