The fact that a process sustains itself does not mean it started the disease, nor does it necessarily follow that shutting it down will cure the disease even though that is what we do in modern medicine: In diabetes we lower glucose without reversing insulin resistance. In heart failure, we reduce sympathetic tone instead of addressing the underlying myocardial injury. In chronic pain, we treat the pain but almost never the underlying pathology. With dysautonomia, we treat the nervous and vascular systems but never the immune. Modern medicine, in an effort to keep everyone on as many drugs as possible, has deeply distorted our understanding of causal heirarchy and etiology. It's medicine's greatest grift. Examples of etiology(cause, not mechanism): viruses, bacteria, improper diet, taxation, emotions, trauma...

The seeming consensus that T cell exhaustion and autoimmunity are the primary lesions in Long Covid has not yet been distinguished from persistent antigenic cause. IOW, IgG transfer recreating symptoms does not have to be autoimmune(can be FcyR) and T cells exhaustion is likely part of if not downstream from dysfunction in other immune cell subsets.

T cell exhaustion is not the primary lesion in Long Covid and ME but it’s a lot closer than nervous system dysregulation. healthrising.org/blog/2026/0…