So proud to finally announce the publication of our most recent study examining PARP14 target selection using TLC-MALDI-TOF in @MDPIOpenAccess! Zeeshan Javed and his team of ten undergraduates in my lab did an awesome job expanding our understanding of proximal targeting.
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Ever get the feeling that you are an imposter in the lab or that your experiments always fail? Me too! That's why I wanted to share some thoughts on the necessity of failure to the scientific mindset in our Scientific Mindset summer series here at SCDI.
Curious what our students have been up to at their Scientific Mindset sessions in the summer here at SCDI? Check out this piece from Dr. Carter-O'Connell on the necessity of failure to the scientific mindset: tinyurl.com/yc2cr4pj
Thanks to @KorinWheeler and @scuciocca for inviting me to join the series this summer, and @FailureMindset for guiding my thinking about this essential topic. I can't wait to see what my failures teach me today!
So proud to finally announce the publication of our most recent study examining PARP14 target selection using TLC-MALDI-TOF in @MDPIOpenAccess! Zeeshan Javed and his team of ten undergraduates in my lab did an awesome job expanding our understanding of proximal targeting.
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Congrats to Zeeshan ('22), Hannah Nguyen ('24), Kiana Harker ('24), Christian Mohr ('25), Pia Vano ('23), Sean Wallace ('19), Clarissa Silvers ('22), Colin Sim ('22), Soumya Turumella ('22), Ally Flinn ('24) and Anthony Moritz ('25) for all their hard work! #SCUProud
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If you are still here and interested, check out the whole story at mdpi.com/1420-3049/28/16/606…
We are happy to share how we use TLC-MALDI-TOF to look at these PTMs and are always open to collaborations exploring this fascinating enzyme class!
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I am thrilled to announce that I have been awarded the @NSF GRFP! I am very honored and am excited to continue my work studying TCRs and cancer bioinformatics.
Failure may reflect:
-what you have learned up until now
-what you are capable of right now
-the circumstances you currently face
But, failure does not define:
-who you are as a person
-your value or worth in this world
-the direction or destination of your future
Thanks to the wonderful faculty and students in the Chemistry Dept. @UOPacific for the invite to share our work at this week's Cheminar! I had a great time visiting the department and hearing about all the exciting research projects you are pursuing!
My team has just updated our already large database of PhD/Graduate fellowships and graduate student research funding opportunities.
We found 200.
For each fellowship, we provide link, description, deadline, eligibility, etc.
Download here: research.jhu.edu/rdt/funding…
ICYMI: Check out this cool review of the ongoing battle btwn hosts and pathogens from the Daugherty lab! Exciting to see some undergrads get their first published manuscript!
Excited to see that our review on evolutionary conflicts between viral proteases and the host immune system is out! frontiersin.org/articles/10.…. This was a great team effort, led by the fantastic @BriBerryTea and @lizfay20, and an outstanding group of undergraduates in the lab.
@SCU_ChemBiochem is getting excited for a "Spooky Scavenger Hunt" this Friday at 4 pm! We are going to "trick or treat" through the Chemistry & Biochemistry research and teaching labs and explore the haunted NMR in our new SCDI building. Come join us for food and fun!
Interested in meeting some of the fantastic people in the Chem-Biochem Dept.? Would you be more interested if candy were involved? Either way, come trick or treat with us this Friday at 4PM in the new SCDI building!
I cannot recommend the Cohen lab highly enough as a place to compete a postdoc! If you are looking for a dynamic, inclusive lab that values big swings, you should really consider applying. Plus, the PNW is a great place to live!
They demonstrate that this technique works with both peptides and proteins, using it to find a new PARP14 selective substrate peptide. And, it can be used with chemical treatments to determine acceptor site chemistries.
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A big shoutout to the Fuller lab @SantaClaraUniv for helping us make peptides for this work. We are happy to share any details on how to adapt this technique in your lab and we hope it helps you learn more about the PARP family!
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I'm so excited to announce our new paper - Rapid Analysis of ADP-Ribosylation Dynamics and Site-Specificity Using TLC-MALDI (bit.ly/3BH4Hpe) - dropped today in @ChemicalBiology!
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Our team of enterprising undergrads - led by co-authors Sean Wallace and Leila Chihab - used a neat MALDI trick to analyze multi-site ADP-ribosylation in the closely related PARP14 and PARP15 enzymes.
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