scientist, father, founder/CEO of @PhaseGenomics; tweets are my own and probably not the position of the company.

Joined October 2013
594 Photos and videos
Social distancing #PNW style.
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It's-a me!
Catch us at a conference: @ivanliachko takes the stage at @FutureinReview on 6/1 for a panel called “Gut Feeling: Hacking Your Microbiome”. Later that week, from 6/4 to 6/7, he’ll be on the ground at ASM Microbe 2026 in DC. Say “hey 👋” and connect for the latest in Hi-C!
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Ivan Liachko 🇺🇦 @ivanliachko.bsky.social retweeted
The biggest sustainability challenges are rooted in biology we’re still learning to understand. Hi-C helps build better genomes and unravel microbial communities that support healthier soils, stronger crops, and more resilient ecosystems. Happy 🌎 Day from Phase Genomics.
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Ivan Liachko 🇺🇦 @ivanliachko.bsky.social retweeted
Long reads get you contigs. Proximo™ Hi-C Kits for Plants get you chromosomes you can put to work or meaningful trait / QTL mapping and functional analysis. Tell us about your research and take 20% off through May 1👇 info.phasegenomics.com/hi-c-…
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Chatting with Jeff about their recent oat pangenome paper 🌱🧬. #plants #genome
One oat line has more structural variation than a panel of wheat lines. That finding, from the 1st chromosome-scale oat assembly, led to a 30-line hexaploid oat pangenome published in @Nature using HiFi Hi-C. Full breakdown from senior author Jeff Maughan, PhD, in the clip below
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Ivan Liachko 🇺🇦 @ivanliachko.bsky.social retweeted
New in the Journal of Water and Health: ProxiMeta™ Hi-C metagenomics improves antimicrobial resistance tracking in wastewater. Key findings: → 2,816 traits detected → 554 genes linked to hosts → 52.9% of genes were ARGs 🔗iwaponline.com/jwh/article/2…

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Ivan Liachko 🇺🇦 @ivanliachko.bsky.social retweeted
32% off ProxiMeta™ Hi-C kits ends 3/15 (then save 16% through end of month). You’ll get: ✅ High-quality MAGs from complex samples ✅ More complete genomes than traditional binning ✅ Accurate host attribution for phages, plasmids, and AMR genes 👉info.phasegenomics.com/march…
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Ivan Liachko 🇺🇦 @ivanliachko.bsky.social retweeted
March MAGness is here! Score special pricing on ProxiMeta™ Hi-C kits for metagenomics & microbiome studies in everything from complex soil samples, to gut microbiomes, to bioreactors: 🔬 32% off | March 2–15 🔬 16% off | March 16–31 Get started here 👇 info.phasegenomics.com/march…
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Ivan Liachko 🇺🇦 @ivanliachko.bsky.social retweeted
FISH finds what it's looking for, and only what it's looking for. In a new study in @AjHematologyshows, Hi-C confirmed FISH findings, plus chromothripsis, CN-LOH & complex rearrangements that FISH probes can’t pinpoint. 🔗onlinelibrary.wiley.com/doi/…
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Ivan Liachko 🇺🇦 @ivanliachko.bsky.social retweeted
New Nature Plants study using Proximo™ Hi-C shows how a hybrid eelgrass species inherited low-light tolerance genes from its deep-water parent that could change how we approach coastal restoration. More from Todd Michael, PhD & team at @salkinstitute 📄 nature.com/articles/s41477-0…
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Ivan Liachko 🇺🇦 @ivanliachko.bsky.social retweeted
New Publication in @PLOSBiology : Optimized Hi-C analysis (Z-score filtering) boosts specificity & reveals virus-host interactions using Phase Genomics’ ProxiMeta™ Hi-C: 79 genus-level matches 293 new linkages in well-studied, climate-critical soils. journals.plos.org/plosbiolog…
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Ivan Liachko 🇺🇦 @ivanliachko.bsky.social retweeted
"A year and a half ago, we couldn't have resolved this hybrid genome." New tech (long reads Hi-C) let researchers separate parental haplotypes in eelgrass revealing which genes drive low-light tolerance. Todd Michael (@genomeslab) breaks down how:
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Ivan Liachko 🇺🇦 @ivanliachko.bsky.social retweeted
Thrilled to share our labor of love over the last 5 years! Leveraging long-read metagenomics we identified several previously unknown phage families that are highly prevalent in the human gut microbiome. Lead by @hanrong_chen [1/5] biorxiv.org/content/10.64898…

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Ivan Liachko 🇺🇦 @ivanliachko.bsky.social retweeted
Tissue prep drives variability early in Hi-C workflows. A new STAR Protocol adds cryogenic tissue grinding before crosslinking, with safe pause points for optimized lab workflows. See how it improves reproducibility & library quality ⬇️ star-protocols.cell.com/prot…

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Ivan Liachko 🇺🇦 @ivanliachko.bsky.social retweeted
Phase Genomics IRL: a few days together in Portland for real-time collab & creativity. Aligning on new products, pressure-testing ideas, a little fun behind the wheel. It’s how we build even better Hi-C tools for the researchers who rely on them. A few of our favorite moments👇
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Ivan Liachko 🇺🇦 @ivanliachko.bsky.social retweeted
Combining @PhaseGenomics and @PacBio HiFi allowed acquisition of the complete 🦠genome. It is composed of 1 chromosome and 2 plasmids, which are mobilome-rich, encoding prophages, an orphan CRISPR array, and complete pathways for many novel and essential cofactors, including heme
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Time for our End of Year sale! If you need an excuse to talk to me about science, this is one way to get there (but also, I'll do it for free 🧬 ❤️ )
Save 25% on Hi-C kits through Dec 31. From complex plant genomes to metagenome binning, Phase Genomics brings clarity to your toughest research questions. Email info@phasegenomics.com with "25 in '25 Kit Promo" in the subject line to claim your discount.
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Ivan Liachko 🇺🇦 @ivanliachko.bsky.social retweeted
🌿 Scientists have produced a high-quality, chromosome-scale genome for American pickleweed, a salt-loving, tetraploid marsh plant. With ~80k genes and detailed methylation data, this resource paves the way for understanding salt-tolerance and supporting salt-marsh conservation.
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Ivan Liachko 🇺🇦 @ivanliachko.bsky.social retweeted
New at #AMPath2025: He Fang, PhD, will showcase Genomic Proximity Mapping® (GPM) and CytoTerra® in #sarcoma. Stop by Level 2, 258ABC on 11/13 from 2:30 – 3:30 pm ET to discover how GPM uncovers hidden structural variants and mosaicism in challenging archival samples.
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Ivan Liachko 🇺🇦 @ivanliachko.bsky.social retweeted
🌿 New in @NaturePlants! Researchers used Phase Genomics’ Hi-C to build a haplotype-resolved chromosome-scale #genome of a hybrid eelgrass (Zostera marina × Z. pacifica), revealing genomic clues to low-light tolerance that could boost coastal restoration. nature.com/articles/s41477-0…
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