NHMRC Emerging Leadership Fellow | Postdoctoral Research Officer | Translational Neurogenomics Lab @QIMRBerghofer | Psychiatric Genetics

Joined March 2013
Photos and videos
Jackson Thorp retweeted
6 Dec 2024
You've heard of DNA, but what about GNA? New preprint from @jacksonthorp and IBG member Andrew Grotzinger that introduces Genomic Network Analysis (GNA), an open-source multivariate tool for performing network analysis using GWAS summary statistics medrxiv.org/content/10.1101/…
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We are hiring postdocs! Join the @DerksEske lab in warm and sunny Brisbane! Get in touch if you are interested in 1) multivariate genetic modelling of psychiatric/related traits; and/or 2) functional interpretation of GWAS loci/drug repurposing. More info seek.com.au/job/75121783?ref…

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Jackson Thorp retweeted
9 Aug 2023
An exciting study by Burstein et al. investigated the genetics of binge eating disorder. We discuss the main findings of their work nature.com/articles/s41588-0… @zac_gerring @jacksonthorp @QIMRBerghofer @NatureGenet

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Our new paper identifying drug repurposing candidates for anxiety is out now! authors.elsevier.com/c/1hRPH… Big congrats to @DWoodward92 for his first publication. Many more great papers to come.

My first publication is now out in Psychiatry Research! Investigating drug repurposing candidates for treatment in anxiety. Huge thanks to co-authors @zac_gerring @DerksEske @jacksonthorp @AkosileWole @egamazon & Jue-Sheng Ong @QIMRBerghofer authors.elsevier.com/c/1hRPH…
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Jackson Thorp retweeted
21 Mar 2023
Ever wondered how many symptoms make up all of adult psychopathology described in the DSM-5? It’s 628! How many do you think repeat across multiple diagnoses? If you answered 231 symptoms repeating a total of 1022 times (median 3 times per symptom, range 2-22), good job! 🧵
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The last of my PhD papers is now published! We looked at the association between depression PRS, trauma exposure, their interaction, and individual depression symptoms @PsychiatryResJ Big thanks to @DerksEske @zac_gerring and all co-authors authors.elsevier.com/a/1gZoD…

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Jackson Thorp retweeted
Today, our paper on attrition and selection using data from the Australian Genetics of Depression study was published. (1/8) doi.org/10.1007/s00406-022-0…

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Our article summarising some of the key challenges for the field of psychiatric genetics is out now in @NatureGenet. As always, an absolute pleasure to write this with @DerksEske and @zac_gerring @QIMRBerghofer nature.com/articles/s41588-0…

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Jackson Thorp retweeted
In a slight shift in focus, our most recent study, published today in @NatureComms, was a large GWAS meta-analysis of acne. Using data from 9 research centers around the globe we were able to identify 46 variants associated with acne risk (29 novel).
Better understanding of the genetic basis of acne can pave the way to more effective treatments. Here, the authors perform a genome-wide association study meta-analysis of >20,000 cases and identify 29 new acne susceptibility loci nature.com/articles/s41467-0…
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Jackson Thorp retweeted
Our preprint exploring sociodemographic and genetic factors linked to optional prescription record linkage in the AGDS is out! Thanks to everyone involved in this important study!
Phenotypic and genetic factors associated with differential consent to record linkage for prescription history in the Australian Genetics of Depression Study medrxiv.org/cgi/content/shor… #medRxiv
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Jackson Thorp retweeted
Excited about my new preprint where we looked at genetic evidence of correlation and potential causal relationships between a panel of ~ 50 blood based biochemical markers and 10 psychiatric traits. @MurrayCairns @miffyjayne @HMRIAustralia @Uni_Newcastle. Short tweetorial 1/13
Genetic estimates of correlation and causality between blood-based biomarkers and psychiatric disorders medrxiv.org/cgi/content/shor… #medRxiv
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Our paper modelling symptoms of anxiety, depression and neuroticism is now out in @NatureHumBehav Link to paper: rdcu.be/ciK6a Big thanks to @DerksEske @AdrianCamposG @zac_gerring @QIMRBerghofer

Symptom-level modelling unravels the shared genetic architecture of anxiety and depression buff.ly/32f2cdw From @jacksonthorp et al. @DerksEske
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Jackson Thorp retweeted
22 Mar 2021
Exciting new work by Gaby Lunansky et al. on #network #resilience. frontiersin.org/articles/10.…
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Jackson Thorp retweeted
Many psychiatric disorders and substance use outcomes share genetic effects. Controlling for genes associated with socio-economic outcomes changes the genetic relationships between these mental health outcomes. Our paper just out in @NatureHumBehav 🧬💸🧠 nature.com/articles/s41562-0…
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Jackson Thorp retweeted
A systematic analysis of genetically regulated differences in gene expression and the role of co-expression networks across 16 psychiatric disorders and substance use phenotypes biorxiv.org/cgi/content/shor… #bioRxiv

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Jackson Thorp retweeted
28 Jan 2021
Faculty of Health @RealHealthM - Brittany Mitchell Exploring the genetic relationship between hearing impairment and Alzheimer’s disease. eprints.qut.edu.au/206652/ #BrittanyMitchell

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Jackson Thorp retweeted
18 Dec 2020
Happy Friday everyone! Our new pre-print is out! In it we explore how the genetic aetiology varies through systematic addition of components in a diagnosis of major depressive disorder (impairment, duration etc.). Welcome any thoughts! medrxiv.org/content/10.1101/…
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