Chemist turned neuroscientist. @MGHMartinos @MGHImaging. Editor-in-chief of @ACSChemNeurosci.

Joined November 2013
76 Photos and videos
1.17 billion people now live with a mental health disorder. Mental illness is the #1 cause of years lived with disability on Earth. And in 90 countries, <5% of people with major depression get minimally adequate treatment. Awareness ≠ treatment. aetherinmind.substack.com/p/…

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If you want to follow my content, check out my Substack at aetherinmind.substack.com/

Want to hear about the evolution of psychiatry and anxiety? Check out my conversation with Jerry Rosenbaum.
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Want to hear about the evolution of psychiatry and anxiety? Check out my conversation with Jerry Rosenbaum.
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Jacob Hooker retweeted
Our latest paper describes automated synthesis and preclinical imaging of a novel [18F]Fluorolidocaine analog via sequential C-H radiolabeling and is out in @rsc_medchem. Congrats @MadisonFrazier1 (1st paper!) @jays_wright @afallenbrooks. Read it here: pubs.rsc.org/en/Content/Arti…
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Jacob Hooker retweeted
@Eikonizo is excited to be in Philly for the @alzassociation #AAIC24. A great opportunity to learn from and meet with some of the best and brightest in dementia research. If you see our CEO @RickLundberg, be sure to stop and say hello!
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Jacob Hooker retweeted
Wow. The Harris team are out of the blocks in lightening quick time with this superb ad x.com/AdamJSmithGA/status/18…

Community note
This ad is from the 2020 Democratic Primary Campaign. newsweek.com/kamala-harris-…
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Jacob Hooker retweeted
📢Stay up to date with the latest📢 This new collection of #ACSChemNeuro research joins the discussion around #MDMA as a potential breakthrough therapy Read the latest research ➡ go.acs.org/9Mn
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Jacob Hooker retweeted
And that's a wrap on #BIO2024! Our CEO, @RickLundberg, spent a busy few days meeting with #biotech & #pharma industry partners and investors while still making time to enjoy some of the sights in beautiful San Diego.
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Jacob Hooker retweeted
📢New collection of #ACSChemNeuro research as the FDA is expected to announce a decision on a new treatment involving #MDMA today ⏰ Read the latest research ➡ go.acs.org/9Er
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Jacob Hooker retweeted
FDA Advisory Committee votes against recommending Lykos' #MDMA treatment for PTSD Read our latest MDMA research here ➡ go.acs.org/9Er
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Jacob Hooker retweeted
Super interesting discussion about expectancy bias… check out pubs.acs.org/doi/10.1021/acs…
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Overall, I thought the discussion was less focused on the tremendous unmet need. Maybe I’m a bit too cavalier, but I certainly felt the benefits outweigh the risks (with plenty of guardrail caveats).
Replying to @ACSChemNeurosci
@jmhooker @zenbrainest want to kick off the discussion?
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Jacob Hooker retweeted
Fascinating discussions online today surrounding the FDA's consideration of a new #MDMA treatment for PTSD 🤔 When is a double-blinded study not enough? How can you blind for a treatment that includes such pronounced and well-known effects? Let us know what you think! ⬇
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Jacob Hooker retweeted
28 May 2024
Today the world can watch a film that has been called “the best movie I have seen in 30 years.” For Love & Life: No Ordinary Campaign is now streaming on @PrimeVideo. After you watch the documentary, please review it on the Amazon page for the film. amazon.com/gp/video/detail/B…
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Jacob Hooker retweeted
16 May 2024
Whoo hoo! Major paper now out in @science : "AlphaFold2 structures guide prospective ligand discovery" Collaboration with @RothLabUNC @BShoichet Skiniotis, Kruse, @EnamineLtd
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2 May 2024
An orangutan in Sumatra surprised scientists when he was seen treating an open wound on his cheek with a poultice made from a medicinal plant go.nature.com/3UrXtjk
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27 Apr 2024
Neuroimaging, blood proteomics, and health data from 30 military personnel show that increased exposure to explosive blasts was associated with structural and functional brain alterations and a decrease in health-related quality of life. In PNAS: ow.ly/bfNA50RpWfO
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25 Apr 2024
Really excited to share the hard work of a killer team. This project was a long time in the making and hit the COVID shutdown timeline and “penalty” but the team saw it through and it’s really great science. @ACSCentSci pubs.acs.org/doi/10.1021/acs…
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Jacob Hooker retweeted
Multidisciplinary team at @MGHMartinos @MGH_CNTR studied 30 active-duty U.S. Special Operations Forces: pnas.org/doi/10.1073/pnas.23… Increased blast exposure was associated with structural, functional and neuroimmune changes in the brain detected by MRI & PET: massgeneral.org/news/press-r…
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Jacob Hooker retweeted
Impact of Repeated Blast Exposure in Active-Duty U.S. Special Operations Forces: pnas.org/doi/10.1073/pnas.23… We thank the 30 SOF participants, who bring the military one step closer to a diagnostic test for repeated blast brain injury. @MGHNeurology @MGHMartinos @MGH_CNTR
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