PhD - St Andrews 2024 🏴󠁧󠁢󠁳󠁣󠁴󠁿 Medicinal Chemist

Joined June 2020
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The rumours are true! Yesterday I passed my viva, concluding my time at St Andrews 🏴󠁧󠁢󠁳󠁣󠁴󠁿 Thank you to all the mentors who have guided me and to all the colleagues on this journey with me. Now on to more chemistry…🧪
A huge congratulations to the newly minted Dr McGuff on passing his viva yesterday to conclude a hugely successful PhD! @john_mcguff Big thanks to @RhPdCu and @SPThomasGroup for doing the honors!
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John McGuff retweeted
Many thanks to the organisers at OSSC 2024! There were many fascinating discussions on chemistry, as well as insightful early career advise! Group members @MashaMazhuga, @TimHilton98, and Tom presented their posters, with Masha picking up a poster prize! #OSSC2024
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John McGuff retweeted
Fantastic day yesterday for the annual @RSCPerkin meeting, this year at @dundeeuni. Plenty of brilliant talks and posters, not least from our own @TimHilton98 and @MashaMazhuga! @DDU_Dundee @StAndrewsChem
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A fascinating dive into the chemistry of germanium. Thank you to colleagues, funding bodies, and collaborators who made this work possible. @StAndrewsChem @BurleyResearch @StAndrewsXray
A new element makes its way into the Watson Group repertoire! Check out our first foray into the world of germanium in the context of CuAAC chemistry, in collaboration with @BurleyResearch! The pre-print is available here on @ChemRxiv: chemrxiv.org/engage/chemrxiv…
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Get to know John J. Molloy (@Johnjmol) in this #YoungCareerFocus 👨‍🔬. Discover the academic journey of this 2024 Thieme Chemistry Journals Awardee and explore the research that earned him this recognition 🎉: 📖 brnw.ch/21wJDWT
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Great work from former group member @MattJAndrews within a fantastic team! Congratulations also to those from @BurleyResearch, @LloydJonesLab, and @GSK for providing fascinating mechanistic insights into ynamine-based CuAAC chemistry!
Our latest publication from the group is out in @J_A_C_S . Great collaboration with @allanjbwatson @LloydJonesLab and @GSK exploring t why ynamines are great click substrates. Work is supported by @LeverhulmeTrust @GSK @EPSRC @BBSRC pubs.acs.org/doi/10.1021/jac…
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Congratulations to @john_mcguff and @_marekvarga, as their work on the synthesis of complex BOBs via Rh-catalysed [2 2 2] cycloaddition has been highlighted in @OPRD_ACS! pubs.acs.org/doi/10.1021/acs…
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Very pleased to now be Dr Kane 🎉 a dramatic close to an incredible 3.5 years in the Watson lab, and it was great to meet @VarinderAggar11 in the process to talk all things boron 🧪
Congratulations to our Boron Boii @KaneACB for passing his viva today and becoming Dr. Bastick! A traditional plunge into the sea marks the end of a great 3.5 years - not a bad effort for a Natural Scientist 😉 Many thanks to @VarinderAggar11 and @ADS10_StAndrews for examining!
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One of the top cited #SYNLETT articles in 2023 you shouldn´t miss! by Kane Bastick and Allan Watson @watson_group @StAndrewsChem free access 👉 brnw.ch/21wJqT4 #boron #catalysis #chemoselectivity #homologation #diversityorientedsynthesis
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Happy to share some recent work on a dynamic kinetic asymmetric transformation just out in @ChemicalScience with @ADS_StAndrews. Well done everyone involved, especially Aífe (now in Manchester @greaneygroup)! #compchem @ADS_GroupStA @StAndrewsChem pubs.rsc.org/en/content/arti…
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3 Apr 2024
Day 2 at Edinburgh Science Festival! Happy to be here as a part of Boron:Beyond the reagent @EPSRCboron @StAndrewsChem @EdSciFest @EdinburghChem @UoMPharmaOpt
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Another chapter in the [2 2 2] odyssey! We investigate the substrate scope of internal alkynes in our process, metal-ligand recovery as well as catalyst reactivation.
Congrats to @john_mcguff for publishing this neat work in Synlett, assessing the scope and limitations of unactivated internal alkynes for Rh-catalysed [2 2 2] cycloadditions! @StAndrewsChem @thiemechemistry thieme-connect.com/products/…
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John McGuff retweeted
Our second #PhDposition is in synthetic methodology playing with palladium and novel organoboron reagents - see our website to make informal inquiries watsongroup.wp.st-andrews.ac…

ALT Fifth Element Silence GIF by zoefannet

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Congrats to @john_mcguff and @_marekvarga, whose stellar work on complex benzoxaborocycles (BOBs) has been highlighted in synfacts! @thiemechemistry thieme-connect.de/products/e…

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John McGuff retweeted
Accessing Rare alpha-Heterocyclic Aziridines via Bronsted Acid-catalyzed Michael Addition/Annulation: Scope, Limitations, and Mechanism (Allan J. B. Watson and co-workers) @timhilton98 @allanjbwatson @watson_group @StAndrewsChem onlinelibrary.wiley.com/doi/…

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28 Feb 2024
Out now on synthesis workshop! The full story behind the development and applications of our Pd-catalysed boron homologation last year with @watson_group . Many thanks to @MatthewHorwitz1 for inviting me and Hamideh for editing! @EPSRCboron
Today we have an exciting mid-week bonus talk from Kane Bastick @KaneACB (Watson group, Uni of St Andrews) who shares his work on palladium-catalyzed homologation strategies! Link: youtu.be/-LV3bUHLaNI @ACSCatalysis 2023, 13, 7013. Synlett 2023, 34, 2029. @thiemechemistry
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Always great to work with the @AndySuthLab group! Congrats all! @StAndrewsChem @EPSRCboron
Congrats to @hollymcerlain (@UofGChem) and @MattJAndrews on the discovery of a copper pre-catalyst that allows a step-change in the radioiodination of arenes published in @JOC_OL. Another great collaboration with Sally Pimlott and the @watson_group. pubs.acs.org/doi/10.1021/acs…
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