Associate Professor at University of Oslo. Interested in bioinformatics, 3D Genome, epigenetics, genomics and gene regulation. Postdoc positions available.
Struggling with Hi-C data? Meet hictk: a new toolkit revolutionizing working with .hic and .cool files! Seamless interoperability for a range of file formats, and blazing-fast performance, 3D genomics has just gotten a lot easier. Developer: @robomicsacademic.oup.com/bioinformat…
🚨 PhD in Bioinformatics & Gene Regulation 🚨
Join the Bioinformatics in Life Science initiative through a multidisciplinary project to unravel gene regulation from DNA to proteins, co-supervised by @eviledv@jonnings and me @biovitenskap @NCMMnews!
jobbnorge.no/en/available-jo…
Finally biologists can also use numpy (array programming). Handling e.g. DNA and protein sequences with convenience and speed, like physicists and machine learners for decades have worked with numerical data: nature.com/articles/s41592-0… (1/3)
Epigenetics, gene transcription and cancer research X afficionados...Don't forget to register and join our exciting "nuclear topology and 3D chromatin architecture in cancer" online symposium taking place on Monday November 11th! Organized by @jane_skok and @LabMelnick#epigenetics#cancer@NYUGSOM_Path
🎉 Excited to share the peer-reviewed version of our manuscript describing COBIND, a tool for revealing TF co-binding patterns using non-negative matrix factorization. Great work led by @IevaRau @NCMMnews @NordicEMBL@UniOslo_MED@UniOsloacademic.oup.com/nar/advance…
@NAR_Open
Our lab (papantonislab.eu) is still looking for a PhD candidate with a strong computational biology background and a keen interest for genome assembly and #3Dgenomics to join our subproject in the exciting EvoREST initiative on genome evolution. @yourUMG@uniGoettingen
Last couple of days to apply for this postdoc position to generate deep learning models and expand the great JASPAR and UniBind databases @NCMMnews!
It's a fantastic project in a very supportive group with outstanding collaborators!
Congratulations to Eivind Hovig! And thanks for great collaboration through more than two decades! You have made invaluable contributions to FUGE, @elixirnorway and Norwegian bioinformatics and cancer research!
🎉 Happy 70th Birthday to Eivind Hovig! 🎂🥳 Your outstanding contributions to #bioinformatics have paved the way for groundbreaking research in Norway and beyond. 🧬🇳🇴 Your dedication and expertise are invaluable to us, @UniOslo, @UiO_LifeSci & @Oslounivsykehus. 🏆🔬
Associate professor of Medicine (Biochemistry) position open at Institute of Basic Medical Sciences, University of Oslo!
We are recruiting a new colleague working within the fields of chromatin biology or membrane dynamics!
@UniOslo_MED@WAutophagyjobbnorge.no/en/available-jo…
🎊 2023 ELIXIR All Hands Meeting #ELIXIR23 has come to an end with @NBlomberg’s closing remarks.
👏 Thank you all for joining us in Dublin and we look forward to seeing you again next year in Uppsala, Sweden 🇸🇪 for #ELIXIR24!
@sysbioire#ELIXIR_IE@NBISwe#ELIXIR_SE
We're excited to share our manuscript describing COBIND, a novel tool for the identification of transcription factor co-binding patterns with non-negative matrix factorization
biorxiv.org/content/10.1101/…
1/9
MoDLE, modeling of DNA loop extrusion, from @robomics, @jonnings, simulates DNA contact maps quickly, using low memory. It requires a genome region and the barrier positions in the region eg CTCF binding sites. Predicts effects of deletoins on TADS genomebiology.biomedcentral.…
ALT Comparisoin of MicroC data (top) and MoDLE prediction for a region of Chromosome 2
New preprint out! biorxiv.org/cgi/content/shor…
MoDLE allows simulating HiC-like contacts generated by loop extrusion genome wide in a matter of minutes. Opens up for exploring underlying features of genome structure. Available on the command line. github.com/paulsengroup/modl…@INC_COST
Happy to publish our latest work as a preprint in bioRxiv. DNA methylation can predict and explain response to chemotherapy and bevacizumab. biorxiv.org/content/10.1101/…
Very happy to see the peer-reviewed version of this work out at epigeneticsandchromatin.biom…
We performed expression-methylation quantitative trait loci in 19 cancer types and identified 13 TFs likely driving DNA methylation patterns around their TFBS in at least 2 cancer types 1/6
Our new preprint is out
We found that pioneer TFs are associated with the modulation of DNA methylation patterns around their binding sites in cancer and immune cells across cancers
Led by @RozaBLemma w/ @TF_82 E Martinsen @Vesselinka @ragnhildes1 @oddsgabbiorxiv.org/content/10.1101/…
Happy to share our latest work!
A big thanks to @jonnings for his support and supervision.
Many thanks also to our collaborators for their invaluable comments and feedback @torognes, @AMathelier and Vipin Kumar.
New preprint out! biorxiv.org/cgi/content/shor…
MoDLE allows simulating HiC-like contacts generated by loop extrusion genome wide in a matter of minutes. Opens up for exploring underlying features of genome structure. Available on the command line. github.com/paulsengroup/modl…@INC_COST