There's a mass migration happening in science generally but especially human genomic medical-themed researchers!🧬 When the new US govt kicks in this Musk-owned platform is not where I want to be If you're not already there, come join us 🦋 lcpilling.bsky.social

Minor-ish update to {ukbrapR} to v0.2.9 to fix 2 bugs and improve behaviour of some internal functions github.com/lcpilling/ukbrapR

Wow! Peter Visscher and colleagues have published a provocative paper in Nature speculating that "polygenic gene editing" of embryos might prove effective in reducing disease risk, should the technology advance enough to become safe in the future. The authors argue that for polygenic diseases like type 2 diabetes or schizophrenia, theoretically, editing only a handful of variants might produce dramatic reduction in the disease prevalence among the edited embryos. And this approach will prove more effective than embryo screening. Of course, the authors have acknowledged that this is speculative and discussed all the challenges and ethical issues associated with embryo gene editing. Further, Nature has thoughtfully published a well-balanced News and Views titled "Human embryo editing against disease is unsafe and unproven — despite rosy predictions" by experts in this topic (@ShaiCarmi @WiringTheBrain and @HankGreelyLSJU) arguing that though theoretically possible the idea might never work. Visscher et al. Nature nature.com/articles/s41586-0…

My blood 🩸 made it all the way to University Hospital, Birmingham where it helped to save or improve someone's life Love getting these e-mails. Consider signing up to donate blood, if you don't already blood.co.uk @GiveBloodNHS

📢December Biomarkers @DEMONNetwork working group will host Dr Alankar Atreya discussing how changes in sleep detected by wrist devices are related to Alzheimer's progression. ⌚️ Wed 11th 10am GMT. All welcome - please message for teams details.

🌟Post-doc available in Exeter with the superb @janemasoli researching cardiovascular ageing using health data science approaches This is part of a wider NIHR-funded project studying cardiovascular frailty in routine health data Join us! 🤩 tinyurl.com/yr4e6dkz closes 1 Jan

It is taking a lot of time and e-mails to set up payment to @dnanexus for my group. Still not successful, months after first contacting them! In speaking to others, this is not uncommon. I *really* want to just pay them and get on with @uk_biobank analyses! Any tips?!

Excited to attend @geronsociety annual meeting this year in #Seattle Fascinating programme. Looking forward to learning new things, catching up with old friends, and making new collaborations! Reach out to me if you are also at #GSA2024 and want to connect

Exciting times - We are launching our Phyto Ageing study! Are you over 50 and do you have some joint stiffness in your hands? We need volunteers to see if our plant-based dietary supplement improves your symptoms. eu.jotform.com/form/24275458…

Excited to connect with scientists from around the world at #ASHG2024! If you’re here and interested, come find me at poster 7009 to chat about our #PGx research on statin adherence in #UKBiobank. #Genomics #PrecisionMedicine #Pharmacogenetics

Episode 160 of The Genetics Podcast is live! 🚀 In this episode, @Eric_Fauman, Head of Computational Biology @Pfizer, shares his insights on his career, #AI, and GWAS in drug discovery. Tune in here👇 🎧 link.chtbl.com/EP160?sid=x 📽️ youtu.be/iTt88uoIncA?feature… #genetics #thegeneticspodcast #sanogenetics #precisionmedicine

Last autumn FinnGen hit its target of sampling close to 10% of the Finnish population with more than 500,000 participants. We are happy to announce that the results based on the full cohort are now publicly available for the whole research community: finngen.fi/en/results-based-…

Congrats Rosie. This has to be the best name for a conference session, ever!

This months @DEMONNetworkUK biomarkers working group is on Tuesday with @f_huxford. Details below ⬇️

Microsoft "Bookings" is game changing! Knew it would be useful for students/tutees - but it makes arranging quick meetings with colleagues so much easier too (no more back and forths "can you do then? what about then?")

Happy grant rejection Friday to those of you who observe it #AcademicChatter #AcademicTwitter