@lmalmstroem profile picture
Lars Malmstroem @lmalmstroem

Work as a scientist @ ETH, Zurich. Systems biology, protein structure, infection.

Joined January 2010
  • Tweets 113
  • Following 93
  • Followers 118
Photos and videos
Congrats Aaron for publishing a paper (lars.malmstroem.net/publicat…) in Communications Biology describing a method to increase accuracy when analyzing mass spectrometry data.
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I use SocialKYC to represent my internet identity. @social_kyc_tech 8171302018116681
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Congrats Tommaso for publishing a paper (lars.malmstroem.net/publicat…) in communications biology describing the evolution of ipsilateral breast cancer in humans
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Congrats Carlos for publishing a paper (lars.malmstroem.net/publicat…) in PLoS Computational Biology describing a method to sequence proteins using mass spectrometry
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Lars Malmstroem retweeted
Hamed Khakzad@hamed_khakzad
17 Oct 2021
Happy to share with you our recent study: Opsonization by non-neutralizing antibodies can confer protection to SARS-CoV-2 despite Spike-dependent modulation of phagocytosis. Nice collaboration with @PNordenfelt lab. @lmalmstroem @LHapponen biorxiv.org/content/10.1101/…

Opsonization by non-neutralizing antibodies can confer protection to SARS-CoV-2 despite Spike-dep...

Spike-specific antibodies are central to effective COVID19 immunity. Research efforts have focused on antibodies that neutralize the ACE2-Spike interaction but not on non-neutralizing antibodies....

biorxiv.org
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Lars Malmstroem retweeted
Hamed Khakzad@hamed_khakzad
29 Sep 2021
Happy to share with you our recent publication. Here, we showed how S. pyogenes form serotype specific interaction with human plasma proteins. Nice collaboration with Malmström lab @the_Sounak @lmalmstroem @LHapponen journals.asm.org/doi/10.1128…

Streptococcus pyogenes Forms Serotype- and Local Environment-Dependent Interspecies Protein...

Streptococcus pyogenes (group A Streptococcus [GAS]), is a human-specific Gram-positive bacterium. Each year, the bacterium affects 700 million people globally, leading to 160,000 deaths.

journals.asm.org
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Congrats Sounak for publishing a paper (lars.malmstroem.net/publicat…) in mSystems describing genetic and environmental factors influencing host-pathogen protein interactions.
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Congrats Hamed for publishing a paper (lars.malmstroem.net/publicat…) in Bioinformatics describing Cheetah-MS, a web-server using a fast TX-MS implementation to model protein complexes using mass spectrometry data.
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Lars Malmstroem retweeted
Hamed Khakzad@hamed_khakzad
16 Jun 2021
I’m very happy to make Cheetah-MS (txms.org) available to the community. A web server to rapidly model protein-protein interactions using cross-linking MS data. Do you have suggestions to make this even better? Let us know @lmalmstroem academic.oup.com/bioinformat…

Cheetah-MS: a web server to model protein complexes using tandem cross-linking mass spectrometry...

AbstractSummary. Protein–protein interactions (PPIs) are central in many biological processes but difficult to characterize, especially in complex, unfract

academic.oup.com
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Lars Malmstroem retweeted
Nina van Sorge@N_van_sorge
21 May 2021
Very happy to announce that we have an opening for a PhD student in my group at the Amsterdam UMC. The project aims to unravel how bacterial glycans shape host defense. Please apply before June 23rd! RT please werkenbijamc.nl/vacatures/ph…
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Congrats Tommaso for publishing a paper (lars.malmstroem.net/publicat…) in JPR describing a Proteogenomic workflow linking a molecular phenotype to spiculated tumors.
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Congrats Anahita for publishing a paper (lars.malmstroem.net/publicat…) in ELife describing the use of mass spectrometry to detect host-response patterns during infections.
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Congrats Mahmudul for publishing a paper (lars.malmstroem.net/publicat…) in Chemical Science describing the use of X-ray crystallography and TX-MS to determine the structure DS-Epimerase 1.
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More fun with evolutionary couplings of protein complexes - now going large scale. Glad to finally see this paper out in @NatureComms - and thanks for the collaboration @deboramarks ! - nature.com/articles/s41467-0…
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Lars Malmstroem retweeted
Kevin Drew@kdrew
18 Feb 2021
I am very excited to have an open position for a postdoc to study macromolecular assemblies. Details on the lab's research can be found here: ksdrew.github.io/ Come join us in Chicago! #proteomics, #Bioinformatics, #MachineLearning, #cilia, #proteincomplexes

UIC Department of Biological Sciences@UIC_BioS
18 Feb 2021
The @kdrew lab is accepting application for a #postdoc position to study macromolecular assemblies. Candidates from multi-disciplinary backgrounds are welcome to apply, including those in @computersciences, #Chemistry, #engineering, and #biology bit.ly/3aunOHU
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Congrats Hamed for publishing a paper in Frontiers in Genetics describing the use of TX-MS to study interactions between bacterial surface proteins and the human MAC: lars.malmstroem.net/publicat…
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Lars Malmstroem retweeted
Structural Biology-Chemistry at Institut Pasteur@DBSC_IP
15 Jan 2021
Very interesting integrative study combining modelling, molecular Dynamics, cross-linking and mass spectrometry. Congrats to @yasaman_karami @mjwnilges from our department, and also to @hamed_khakzad @LHapponen @lmalmstroem and co-authors 👏👏👏
PLOS Comp Biol@PLOSCompBiol
13 Jan 2021
Strep. M1 protein interaction with human IgGs block the Fc-receptor binding site and help the bacteria to evade immune defenses - read it here! plos.io/3q8gk21 @hamed_khakzad @yasaman_karami @LHapponen @lmalmstroem
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Lars Malmstroem retweeted
Hamed Khakzad@hamed_khakzad
14 Jan 2021
In vivo Cross-Linking MS of the Complement System MAC Assembled on Live Gram-Positive Bacteria frontiersin.org/article/10.3…

Frontiers | In vivo Cross-Linking MS of the Complement System MAC Assembled on Live Gram-Positive...

Protein-protein interactions are central in many biological processes, but they are challenging to characterize, especially in complex samples. Protein cross...

frontiersin.org
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Lars Malmstroem retweeted
PLOS Comp Biol@PLOSCompBiol
13 Jan 2021
Strep. M1 protein interaction with human IgGs block the Fc-receptor binding site and help the bacteria to evade immune defenses - read it here! plos.io/3q8gk21 @hamed_khakzad @yasaman_karami @LHapponen @lmalmstroem
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