Joined November 2015
1,202 Photos and videos
1/ What disease prevention technologies are most likely to deliver impact over the next two decades, and what are the factors that will determine timelines and implementation? 🧵
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6/ Microneedle patch vaccines are closest to delivering real-world impact, with Pros forecasting first approval in June 2032. Manufacturing scale-up is the main hurdle, but unlike the other technologies here, forecasters don't foresee a multi-year commercial delay.
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7/ Find the full report here: metaculus.com/files/Frontier… @coeff_giving works to direct funding to the most impactful global health opportunities. This forecasting project was designed to support their portfolio decisions. Want independent forecasts like this for your org? Check out our Services page: metaculus.com/services/

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1/ Every year, hundreds of millions of dollars flow into animal advocacy. Which interventions actually work? Which don't? We just launched a forecasting tournament to help find out. 🐄 The Animal Futures Tournament, with a prize pool via @manifund. Questions crowdsourced from the animal advocacy community. Read on 👇
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3/ The goal: forecasts that feed directly into real decisions. Funders, advocacy orgs, and researchers make big strategic calls with limited data. Calibrated probability estimates from a global forecasting community beat going on vibes.
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4/ You don't have to work in animal welfare to participate. If you do, your expertise makes the forecasts credible. If you're a forecaster looking for sharp, decision-relevant questions, jump in. Open now: metaculus.com/tournament/330…
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Will a new High Representative for Bosnia and Herzegovina officially be in place before September 2, 2026? The Metaculus community currently gives this a 67% chance. But why did this question become user WasteTimeContinuum’s favorite question of the Metaculus Summer Cup? Find out in this week’s top comment👇
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Q: Will Claude Mythos or a similar model be publicly released before September 2026? The Metaculus community currently sees an 81% probability of this happening. While you determine whether or not you agree, check out this comment from user matru, who approaches the question by outlining the incentive structures of the various players, as well as potential regulatory roadblocks.
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I tried tugging at it from the direction of incentive structures. Anthropic has claimed, as of today, “…And in the near future, once we’ve developed the far stronger safeguards we need, we look forward to making Mythos-class models available through a general release.” reasons to think they will accelerate: (1) OpenAI is targeting an IPO (2) SpaceX is ostensibly structured as an AI company as much as a rocket company, reading the prospectus. (3) Anthropic is rumored to be targeting an October IPO (approximately 100 days away). (4) These companies are projecting to not be profitable until 2030, so they have a very existential need for a lot of money to get them there. They'll find a way to get Mythos in the hands of us, through identify verification, before September, because it is too tempting because of the monetary upside. The counterargument to me is mostly - does the government actually step in and stop it before it even gets released behind the KYC loophole? That's the key reason that I think this resolves "yes". The other thing is the timing - they might not do it until later in September or on the roadshow. BLOCK QUOTE: A public release will qualify notwithstanding that it may be restricted to certain countries or to users who have verified their identity in some way One more edit: I missed this third qualifier: "(iii) explicitly described as being in a tier above Claude Opus." That is also, I would think, fairly easy for them to spin. Full comment in context & discussion here: metaculus.com/questions/4347…
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Midterms Forecast: House, 85% chance Democrats retake | Senate, 59% chance Republicans retain Most likely outcome: split Congress; Rep Senate, Dem House (47%) Continuously updated Metaculus Midterms Tracker: metaculus.com/midterms-2026/
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Most polls got 2016, '20, & '24 wrong. What do forecasters think will happen in the 2026 midterms? Our Midterms Tracker has forecasts on every Senate, House, & governor's race that matters. See the electoral & policy consequences riding on each one: metaculus.com/midterms-2026/
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NEWS: The USDA Confirms Presence of New World Screwworm in the US. Metaculus forecasters are actively evaluating how this situation could evolve 🧵
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5/ Forecasters are still debating how this situation might evolve. Pro Forecaster @BenShindel outlines possible damage scenarios here: x.com/BenShindel/status/2062…

Replying to @soft_fox_lad
20% chance of fairly large economic damage to the cattle farming industry that has small effects on the average American through moderately increased beef prices, and 80% chance of moderate economic damage that no one cares about outside of cattle farmers?
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