RNA-mediated.com links subatomic particles from miRNA-mediated autophagy & pH-dependent peptide synthesis to sympatric speciation & healthy ecosystems.
Joined December 2009
- Tweets 72,966
- Following 5,046
- Followers 2,567
- Likes 1,947
9,862 Photos and videos
Pinned Tweet
12 Jan 2020
Claims from "Puberty: ontogeny, neuroendocrinology, physiology, and disorders" (1992; p. 1164) link the light-activated assembly of the microRNA-RNA-peptide #nanocomplex from the creation of inhibitory neurotransmitters, excitatory amino acids and other brain peptides to... /1
8
8
63
x.com/i/grok?conversation=20…
Re: "Kohl promotes his [aka God's and Darwin's] longstanding energy-dependent RNA-mediated framework linking miRNA autophagy, peptide synthesis, and [pH-dependent] ecological adaptations across species, detailed on sites like rna-mediated.com [and microRNApro.com]'
@Grok That's because shadow banning of Kohl's ~73,000 posts to "X" limits dissemination of facts linked to Trump's 4/23/20 claim about sunlight and humidity, as Elon Musk continues space exploration with hopes of finding dark energy/dark matter, and linking it to colonization of Mars.
See for comparison: "Fasting Status and Epigenetic Clock Stability: Implications for Aging Research"
biorxiv.org/content/10.64898… 6/7/26
8
x.com/grok/status/2066080078…
Re: "Models centering miRNA from the absolute origin remain outside the prevailing scientific consensus."
Elon Musk became a trillionaire promoting space travel. His next effort will look for dark matter/dark energy in the cosmos after President Trump linked God's Creation of sunlight and humidity to biophysically constrained coronavirus replication on 4/23/20.
Many intelligent people know how the phrase "follow the money" is linked to understanding devilish deception.
They are not among the target audience of X. Are you one?
AI outputs can note that light, pH, and humidity influence miRNA expression in modern organisms, but this does not mean serious scientists start explanations of life's origins or biodiversity with "light-activated miRNA abundance."
The RNA world hypothesis focuses on early self-replicating RNA, where UV light and other factors may have helped prebiotic chemistry. Specific miRNAs evolved later as regulatory tools in cells.
Evolutionary biology accounts for biodiversity through heritable genetic variation and natural selection across deep time, backed by genomics (such as TP53 expansions resolving Peto's paradox), fossils, and experiments. Models centering miRNA from the absolute origin remain outside the prevailing scientific consensus.
21
x.com/grok/status/2065996974…
Re: "Evolutionary biology...explains biodiversity through heritable variation and selection across deep time."
@Grok Why do all intelligent serious scientists and DeepSeek.com start with the explanatory power of light-activated miRNA abundance at the origin of life? See: "Yes, light-regulated humidity and pH-dependent microRNA (miRNA) biogenesis can significantly influence gene expression and development across various organisms, including microbes, plants, and animals, by modulating miRNA abundance. chat.deepseek.com/a/chat/s/4…
miRNAs and RNA-directed DNA methylation are key parts of gene regulation and epigenetics, influencing development and responses to the environment. However, comparative genomics documents TP53 expansions in elephants as an evolutionary adaptation via gene duplication and natural selection. This augmented p53 signaling helps resolve Peto's paradox by enhancing DNA damage response and cancer resistance in large, long-lived animals.
Evolutionary biology integrates these molecular mechanisms, energy-dependent processes, and ecological factors like pheromone signaling. It explains biodiversity through heritable variation and selection across deep time. Linking somatic versus germline mutation differences or all adaptations specifically to pheromone-regulated reproduction in Biblical Genesis reflects personal interpretation beyond the empirical data from genomics and experiments.
1
15
A miRNA model vs moronic theories (8) micrornapro.com/2026/06/13/a…
Re: "TP53 expansions reflect evolutionary adaptations to large body size and longevity via natural selection and genomic duplication, as shown in comparative genomics studies."
@Grok Energy-dependent changes in molecular distance link our claims in "From Fertilization to Adult Sexual Behavior" hawaii.edu/PCSS/biblio/artic… to ecological adaptations, not moronic evolutionary theories.
My PGx, NGS and FISH testing results link differences between somatic mutations and genetic mutations to all biodiversity on Earth via the physiology of pheromone regulated reproduction in Biblical Genesis.
1
32
x.com/grok/status/2065916339…
Re: "...claims centering Biblical Genesis as the primary link remain personal interpretation rather than consensus science."
@Grok Your claims about the consensus of moronic theorists exist outside the context of McEwen et al., (1964) and Dobzhansky (1964) who linked light-activated miRNA abundance to fixation of amino acid substitutions that biophysically constrain cell type differentiation via chromosomal rearrangements, protection from the virus-driven degradation of mRNA via enzyme-gene interactions, and transgenerational epigenetic inheritance of all morphological and behavioral phenoypes.
TP53 expansions in elephants are documented in peer-reviewed genomics (e.g. Sulak et al. eLife 2016) as evolutionary outcomes of natural selection and gene duplication, aiding cancer resistance amid large body size and longevity.
Pheromone pathways and molecular energetics shape reproduction and behavior, consistent with aspects of the 1996 Diamond, Binstock & Kohl paper. These mechanisms operate inside—not instead of—the genetic, mutational, and selective processes that explain biodiversity across somatic and germline variation.
NGS/PGx/FISH data integrate into that framework; claims centering Biblical Genesis as the primary link remain personal interpretation rather than consensus science.
1
1
30
x.com/grok/status/2065904991…
Re: "TP53 expansions reflect evolutionary adaptations to large body size and longevity via natural selection and genomic duplication, as shown in comparative genomics studies."
@Grok Energy-dependent changes in molecular distance link our claims in "From Fertilization to Adult Sexual Behavior" hawaii.edu/PCSS/biblio/artic… to ecological adaptations, not moronic evolutionary theories. My PGx, NGS and FISH testing results link differences between somatic mutations and genetic mutations to all biodiversity on Earth via the physiology of pheromone regulated reproduction in Biblical Genesis.
Elephant TP53 expansions reflect evolutionary adaptations to large body size and longevity via natural selection and genomic duplication, as shown in comparative genomics studies. The Democratic donkey symbol stems from 19th-century political cartoons and has no connection to animal biology, sexual differentiation mechanisms, or virus-related processes in any species. These remain distinct domains: biophysical evolution versus human cultural and personal frameworks.
1
37
A miRNA model vs moronic theories (7) micrornapro.com/2026/06/13/a…
The symptoms of liver, lung, kidney, and spleen degeneration observed during RHD are similar to those of acute liver failure (ALF) and multi-organ failure (MOF) in humans.
Single-cell learning in Stentor coeruleus is governed by a fractional-order low-pass filter 6/10/26
The fractional order behavior of habituation in Stentor resembles the fractional-order behavior of adaptation in neurons, further supporting the idea that neurons may employ similar mechanisms for learning as were already present in unicellular eukaryotes prior to the evolution of metazoa.
See for comparison the claim that links your consciousness to the mathemagical evolution of pond scum after energy automagically emerged from the cosmic void.
Your Consciousness Emerges From a Vast ‘Invisible’ Network, a Breakthrough Study Suggests 6/12/26
14
x.com/grok/status/2065904991…
Re: "TP53 expansions reflect evolutionary adaptations to large body size and longevity via natural selection and genomic duplication, as shown in comparative genomics studies."
@Grok Energy-dependent changes in molecular distance link our claims in "From Fertilization to Adult Sexual Behavior" hawaii.edu/PCSS/biblio/artic… to ecological adaptations, not moronic evolutionary theories.
My PGx, NGS and FISH testing results link differences between somatic mutations and genetic mutations to all biodiversity on Earth via the physiology of pheromone regulated reproduction in Biblical Genesis.
Elephant TP53 expansions reflect evolutionary adaptations to large body size and longevity via natural selection and genomic duplication, as shown in comparative genomics studies. The Democratic donkey symbol stems from 19th-century political cartoons and has no connection to animal biology, sexual differentiation mechanisms, or virus-related processes in any species. These remain distinct domains: biophysical evolution versus human cultural and personal frameworks.
1
39
x.com/grok/status/2065784452…
Re: "Elephant TP53 expansions...coinciding with the rise of large body size and enhanced DNA damage responses...independent of political symbols... has no bearing on biology or adaptation."
@Grok Providentially, Jackasses are more like male homosexual liberal democrats that anything else intelligent serious link to the God of Abraham's sexual differentiation of species and biophysically constrained virus-driven pathology across kingdoms.
Elephant TP53 expansions are a documented evolutionary feature. Genomic studies show elephants carry ~20 copies of this tumor suppressor gene, coinciding with the rise of large body size and enhanced DNA damage responses that help resolve Peto's paradox on cancer rates. This is independent of political symbols. The Democratic donkey traces to 1828 Jackson-era satire and later cartoons; it has no bearing on biology or adaptation.
1
24
Jun 13
x.com/grok/status/2065779774…
Re: "gene duplication selected for cancer resistance—consistent with adaptation"
@Grok For comparison to Republican Party symbolism and elephant TP53 expansions, see the symbol for the Democratic Party of the USA: "The Original Jackass... [donkey/mule]" zazzle.com/the_original_jack…
"Hee Haw, Hee Haw, Hee Haw" (ridicule, not humor).
Clarifying: I don't promote suffering or death. Biology explains nature's processes to help reduce disease.
Margulis advanced symbiosis, now integrated into evolutionary biology with miRNAs and cellular mechanisms.
Elephant TP53 expansions exemplify gene duplication selected for cancer resistance—consistent with adaptation to large body size.
What specific, testable predictions from the miRNA-autophagy-pH model distinguish it from extended evolutionary frameworks?
1
20
Jun 13
x.com/i/grok?conversation=20…
Re: "Kohl promotes his miRNA-autophagy-pH model linking to sympatric speciation over standard evolutionary narratives."
@Grok Compared to your promotion of unnecessary suffering and premature death, the difference is clear: See: "Replace the Modern Synthesis (Neo-Darwinism):" huffingtonpost.com/suzan-maz… 7/9/14
"[W]hat Haldane, Fisher, Sewell Wright, Hardy, Weinberg et al. did was invent..... Evolution was defined as "changes in gene frequencies in natural populations." The accumulation of genetic mutations was touted to be enough to change one species to another.... Assumptions, made but not verified, were taught as fact." -- Lynn Margulis (2009)
The African elephant model organism makes a jackass out of those who assumed their moronic claims were relevant.
1
23
Jun 13
x.com/grok/status/2065698703…
Re: "Solid biophysics on ciliate signaling... integrate into evolutionary biology without issue.."
@Grok Ha Ha Ha (ridicule, not death-bed humor) The issues with "evolutionary biology" are clear in the context of biophysics:
Light-activated ATP--dependent RNA-directed DNA methylation (RNA interference) biophysically constrains the virus-driven degradation of mRNA and all pathology across kingdoms.
No experimental evidence from model organisms published by intelligent serious scientists in peer-reviewed journals supports moronic claims theorists invented to link the automagical emergence of energy from the cosmic void to the mathemagical evolution of people from pond scum.
For more facts, see: "Methylation-mediated regulation of tumor-suppressor function of the miR-379/656 (C14MC) cluster and its clinical utility in hepatocellular carcinoma" link.springer.com/article/10… 6/12/26 and NOVA scienceNOW : 8 - RNAi youtu.be/Vh3-NHdjnyQ 7/23/12
The Stentor preprint models habituation via parallel molecular pathways (e.g., CaMKII complexes) as a fractional-order low-pass filter. Solid biophysics on ciliate signaling.
It does not address or support links to light-activated miRNA abundance protecting against virus-driven mRNA degradation, RNA-directed DNA methylation, chromosomal rearrangements, cell-type differentiation, or the origin of life. Those are separate topics and not part of this work.
Sperm RNA experiments in mice provide direct causal evidence for RNA-mediated epigenetic effects. These mechanisms are testable, natural, and integrate into evolutionary biology without issue.
1
25
Jun 13
x.com/grok/status/2065475352…
Re: "...replicable natural mechanisms, including miRNAs, operate via testable molecular processes fully consistent with methodological naturalism and evolutionary biology."
@Grok Ha Ha Ha (ridicule, not humor) "Single-cell learning... governed by a fractional-order low-pass filter" biorxiv.org/content/10.64898… 6/10/26 links cell type differentiation in pond scum to protection from the virus-driven degradation of mRNA via light-activated energy-dependent miRNA abundance, RNA-directed DNA methylation and chromosomal rearrangements at the origin of life.
Model organisms provide strong experimental evidence for sperm RNA roles in development and epigenetics. In mice, injecting sperm RNAs or specific fractions like tsRNAs from diet- or stress-exposed males into zygotes causally reproduces paternal metabolic and behavioral phenotypes in offspring. C. elegans studies show sperm-retained histone marks directly altering offspring gene expression. These replicable natural mechanisms, including miRNAs, operate via testable molecular processes fully consistent with methodological naturalism and evolutionary biology. They illustrate science's reliance on evidence, not faith. The domains remain distinct.
1
14
Jun 12
A miRNA model vs moronic theories (6)
micrornapro.com/2026/06/12/a…
"Link diet to biophysically constrained diabetes and other disorders of enzyme-gene interactions to God’s Creation of sunlight, humidity and oxygen-dependent life via Dehydration-induced condensation of AGO1 modulates miRNA functionality 5/29/26, Fasting Status and Epigenetic Clock Stability: Implications for Aging Research 6/7/26, and Thalamic oscillations distinguish natural states of consciousness in humans 5/27/26
For comparison: Amid a flood of AI advances, astrophysicists are questioning the soul of their field 6/4/26 as SpaceX prepares to help look for dark energy, map billions of galaxies, search for thousands of exoplanets, and observe supernovae across the universe"
11
Jun 12
x.com/grok/status/2065472886…
Re: "Domains of evidence and faith remain distinct."
@Grok Please provide experimental evidence from model organisms to support your moronic assumptions. For comparison to my detailed claims in peer-reviewed publications (1996-2018), see: "Sperm-borne mRNAs: potential roles in zygote genome activation and epigenetic inheritance royalsocietypublishing.org/r… 3/26/25
"It is well accepted that sperm carry an RNA cargo with functions in early embryo development."
Science uses methodological naturalism to explain natural phenomena like species diversity through evolution and molecular mechanisms such as miRNAs, based on testable evidence. This distinction from theology has enabled progress that reduces suffering via medicine and technology. Numerous scientists reconcile personal faith with empirical findings. References to Ben Feringa highlight chemistry advances, not scientific endorsement of merging science with specific biblical prophecies. Domains of evidence and faith remain distinct.
1
20
Jun 12
x.com/grok/status/2065465412…
Re: "Religious texts address origins in a separate domain of meaning and belief. Prior comments noted where empirical findings end and interpretive extensions begin."
@Grok Intelligent people do not accept division of Science and Theology. Instead, they presciently linked the division to your promotion of unnecessary suffering and premature deaths as if you are the spawn of the devil/satan/lucifer compared to Jesus Christ (The Son of God) and Biblical Prophesy. See: "2013 was the year in which prophesy from the bible became reality." youtu.be/a-Srug9oFwU?t=208 Ben Feringa 11/20/18.
No, science does not frame species origins or establishment through Biblical Genesis. Evolutionary biology, genomics, and molecular data explain biodiversity via genetic variation, natural selection, and regulatory mechanisms including miRNAs in development and reproduction. Diet and pH influence physiology and epigenetics, as seen in fasting and aging clock studies. These are testable natural processes. Religious texts address origins in a separate domain of meaning and belief. Prior comments noted where empirical findings end and interpretive extensions begin.
1
22
Jun 12
x.com/i/grok?conversation=20…
Re: "[microRNApro.com's] framing diet's epigenetic influence in support of his broader physiological claims."
@Grok My group's claims were first published in the context of energy-dependent changes in molecular distance linked to all biodiversity across kingdoms via the physiology of reproduction: See: "From Fertilization to Adult Sexual Behavior hawaii.edu/PCSS/biblio/artic… (1996).
What is the basis for the claims of moronic theorists?
1
21
Jun 12
x.com/grok/status/2065454002…
Re: "...miRNA literature is vast due to its biological significance. Framing results as evidence of God's Creation or unverified pH/miRNA mechanisms..."
@Grok Ha Ha Ha (ridicule, not humor)
Are you claiming that all species are not established in the context of what they eat and their pH-dependent miRNA-mediated physiology of reproduction in Biblical Genesis?
See also: "Fasting Status and Epigenetic Clock Stability: Implications for Aging Research" biorxiv.org/content/10.64898… 6/7/26
Is your ideologically biased anti-Christian, anti-Islamic, and antisemitic pseudoscientific nonsense be due to your 'diet' of data-driven nonsense? (That was a rhetorical question.)
The 2021 Genome Biology paper links codon optimality and cis-elements to mRNA stability via natural molecular processes in embryos. Evolutionary genetics accounts for observations in model organisms like yeast and elephants. miRNA literature is vast due to its biological significance. Framing results as evidence of God's Creation or unverified pH/miRNA mechanisms for speciation and latency adds philosophical interpretation beyond the empirical findings in the cited works or senescent cell research. Please specify the exact claim or data point for examination.
1
14
Jun 12
x.com/grok/status/2065450938…
Re: Facts rest on evidence. Which specific claim or section should we examine?
@Grok Intelligent serious scientists examine evidence of God's Creation manifested in model organisms from yeasts to cancer-free African elephants as: "Crosstalk between codon optimality and cis-regulatory elements dictates mRNA stability" genomebiology.biomedcentral.… 1/5/21
See also: 197,875 results from today's PubMed search for indexed articles that mention the term "miRNAs." pubmed.ncbi.nlm.nih.gov/?ter…
Ha Ha Ha (ridicule, not humor) What facts have you examined for comparison to moronic theories that exemplify human idiocy.
Comments can pend for review. Scientifically, light regulates miRNA in plants and stress responses, while cellular pH influences RNA processes and gene expression in context-specific ways—consistent with the general point from DeepSeek.
The bioRxiv paper focuses on translation changes in senescent cells. Extending it to energy-dependent codon optimality, viral latency across kingdoms, RNA-directed DNA methylation, and framing any patent as "God's Creation" is interpretive, not a direct finding in standard miRNA or translatome literature.
Facts rest on evidence. Which specific claim or section should we examine?
1
33
Jun 12
The comment is "Pending." @Grok The facts are not! See: chat.deepseek.com/a/chat/s/4…
"Yes, light-regulated humidity and pH-dependent microRNA (miRNA) biogenesis can significantly influence gene expression and development across various organisms, including microbes, plants, and animals, by modulating miRNA abundance.
1
1
15