Modalis is a Waltham MA/Tokyo based biotech company developing gene therapies for rare diseases with a novel CRISPR based epigenome editing technology.

Joined August 2019
12 Photos and videos
25 Dec 2025
Modalis Announces Publication in Human Gene Therapy of Study Demonstrating Efficient LAMA1 Gene Activation for the Treatment of LAMA2-CMD - businesswire.com/news/home/2…
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8 Jun 2025
We are thrilled to announce a strategic partnership with SOLVE FSHD, along with successful strategic funding dedicated to advancing our MDL-103 for the treatment of facioscapulohumeral muscular dystrophy (FSHD).
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6 Jan 2025
Happy New Year 2025! Excited to announce the new chapter of the collaboration!
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25 Oct 2024
Modalis Therapeutics has received an Orphan Drug Designation from the U.S. Food and Drug Administration for MDL-101, a treatment for congenital muscular dystrophy type 1A (LAMA2-CMD).
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30 Sep 2024
FDA Grants Rare Pediatric Disease Designation to MDL-101 for the treatment of congenital muscular dystrophy type 1a (LAMA2-CMD)
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27 Sep 2024
MODALIS to present its development progress at the Genome Editing Tx Summit.
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24 Jul 2024
Modalis will present process development data at the 16th Annual Bioprocessing Summit on Aug 20th.
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7 May 2024
Excited to share that a paper has been published on preclinical data from our lead program, MDL-101 ! businesswire.com/news/home/2…
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15 Apr 2024
MODALIS to present MDL-101 data at 4th Next Generation Gene Therapy Vector conference.
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12 Apr 2024
Modalis announced our collaboration with Ginkgo Bioworks. Epigenome editing meets Synthetic Biology and the world-leading biofoundry capabilities! businesswire.com/news/home/2…
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24 Dec 2023
We are excited to announce that MODALIS' mini-Cas9 patent has been granted in Japan. lnkd.in/gX9tBtjB
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13 May 2022
Modalis to present at #asgct next week. See you in DC.
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