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yongkeun (Paul) park @moofaca

professor at KAIST | cofounder/CTO of @TomocubeInc. | advisor, The Wave Talk Inc. | biomedical optics | microscopy | physics | waves | biotech

Joined July 2010
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  • Following 1,213
  • Followers 760
135 Photos and videos
Grateful to Joonseok Choi for featuring my work in Pressian’s “Frontiers of Science.” We discussed holotomography—3D, label-free imaging of living cells—and the journey from KAIST research to Tomocube. pressian.com/pages/articles/… #Microscopy #Biotech #Tomocube

"살아 있는 신경세포, 이제 '3D 동영상'으로 볼 수 있다"

박용근 카이스트 물리학과 교수의 경력을 보고 의아했다. 물리학자인가? 공학자인가? 그는 학부에서는 기계공학(서울대학교)을, 대학원에서는 의공학(미국 하버드대학교-MIT 협동과...

pressian.com
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Great to welcome @FredSangyeon back to my lab. From undergraduate researcher in my group to HMS faculty, he is now moving to Rice to expand pioneering work on ultra-small lasers for bio/medical applications. PhD candidates and early postdocs—reach out!
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A heartfelt surprise at #OpticaBiophotonics26. The Michael Feld Biophotonics Award ceremony was originally planned for September, but since I could not attend, @OpticaWorldwide kindly arranged a special moment during the plenary. Deeply grateful to optica and the committee.
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Thrilled to announce our new publication! We introduce iDTT, a technique to map 3D optical “fingerprints” of materials. More stable than laser-based methods, it enables non-destructive 3D analysis for applications from materials science to biomedicine. nature.com/articles/s41566-0…
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Congrats to the Mayo Clinic team on their Nature Immunology study showing SIRT2-mediated deacetylation of LCK (K228) sets TCR signaling magnitude. nature.com/articles/s41590-0…

SIRT2-mediated deacetylation of LCK governs the magnitude of T cell receptor signaling

Nature Immunology - Phosphorylation-dephosphorylation and ubiquitination tune TCR signaling to avoid self-reactivity. Kim and colleagues show that acetylation also modulates TCR signaling.

nature.com
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A compelling step toward quantitative immune signaling. Great to see @Tomocubeinc holotomography used for live-cell analysis. 👏
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Honored to receive the 2026 Michael S. Feld Biophotonics Award from @OpticaWorldwide Grateful to my students, collaborators, and colleagues at KAIST and Tomocube. Biophotonics continues to reveal new dimensions of life through light—especially in quantitative phase imaging.
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optica.org/get_involved/awar…
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Great to see the next generation rising in Quantitative Phase Imaging at SPIE Photonics West (San Francisco). 🏆 Gabriel Popescu Award: Hyobin Cho (UT Austin) 🥇 Best Presentation Awards: Joshua F. Lerner (Duke) and Zih-Ying Fu (Georgia Tech)
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Outstanding science, fair selection, and a powerful reminder of Gabriel Popescu’s legacy in empowering young researchers. Please support the Gabriel Popescu Foundation 👉 gabrielpopescufoundation.org #QPI #PhotonicsWest #YoungResearchers

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New Cell paper from Markus Basan lab (Harvard Medical School) using @Tomocubeinc holotomography Shows how label-free biomass density measurement unlocks quantitative biology in live cells. Beyond imaging. once unimaginable is now experimentally possible. #Tomocube
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See the full text: cell.com/cell/abstract/S0092… For more information or a consultation, please contact: info@tomocube.com

Membrane potential mediates the cellular response to mechanical pressure

Cells in tissues need to know when to start growing and when to stop growing to quickly heal wounds but prevent tumorous overgrowth. Membrane potential allows cells to sense physical forces, includ...

cell.com
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Reviewed 64 HT papers published in 2025 and mapped where the field is heading. HT has moved beyond niche imaging → now a label-free 3D phenotyping platform across cell biology, organoids, pathology & infection, increasingly powered by AI. 👉 arxiv.org/abs/2601.02611
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🧬 Inside the Drosophila Ovariole What if Drosophila oogenesis could be visualized without dyes or fluorescent labels, in its native 3D structure? See: youtu.be/MPIJNWfRqpo #DevelopmentalBiology #Drosophila #LabelFreeImaging #Holotomography #3DImaging

Inside the Drosophila Ovariole: A 3D Journey Through Egg Development

Step inside the Drosophila ovariole and explore egg development in ...

youtube.com
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Here’s a label-free 3D holotomography demo of a Drosophila ovariole, revealing the architecture of egg chambers and developmental stages in a fully quantitative, non-invasive way. @Tomocubeinc
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I’m honored to give a Plenary Talk at the @OpticaWorldwide Biophotonics Congress 2026, alongside great scientists including @E_Beaurepaire and Rebecca Richards-Kortum. ⏰ Abstract & Summary Deadline: December 22, 2025 optica.org/events/congress/b…
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If you are working on: • Biophotonics & translational optics • Advanced microscopy & histopathology • Optical tomography, spectroscopy, or OCT • Brain imaging and neuro-optics I strongly encourage you to submit your work and be part of the 2026 program.
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🚀 Holotomography, now for every lab. We’re proud to launch the HT-X1 mini, bringing 3D label-free live cell imaging to all research labs. 🔹 Compact design 🔹 Powerful @Tomocubeinc technology 🔹 New possibilities in life sciences & medicine 🎥 Watch: youtu.be/FAJuqUFqN4Q?si=-o9u…
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Yesterday we hosted @Tomocubeinc TechDay 2025 with researchers, clinicians, engineers & partners worldwide. We unveiled the new HT-X1 Mini, looked back on a decade of innovation, and shared our vision for life sciences & semiconductors. youtu.be/yxM8oPcLNOI?si=Qde8…
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Tomocube has spent the past decade redefining 3D label-free imaging. Now, we’re ready to share the next chapter. 🚀 Join us for Tomocube TechDay on Mon, Sept 15 at 10 PM (KST). Register: forms.office.com/r/6uay8zRGi…
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We’ll unveil our newest holotomography system and present our vision for the future. - A decade of innovation, setting the stage for the future - First look at breakthrough imaging technology - Insights into our new global strategies & partnerships
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