It felt like the right time for a reminder. This is based on an older interview but almost too relevant today. “On Failure and “Pathological Persistence” in Science“ by Michael Yassa on Medium: medium.com/@myassa_62896/on-…
Unexpectedly, we found that microglia not only activate at the lesion site but also at distant white matter regions, indicating long-range propagation of inflammatory signaling in the brain.
Study findings suggest that permeability of the blood-brain barrier is linked to Alzheimer disease pathophysiology, contributes to cerebrovascular lesions observed on MRI, and is associated with neuroinflammation in middle age: hubs.la/Q03P9Wwp0
📣 Today is a turning point in what we know about brain health.
The results from the U.S. POINTER trial provide the rigorous data needed to say with confidence that healthy behaviors can meaningfully protect brain health across diverse populations in the U.S.
The findings, shared for the first time today at #AAIC25, tested lifestyle programs that simultaneously targeted risk factors. The programs focused on:
✅👟Aerobic exercise
✅🧠Cognitive engagement
✅🥗Nutrition
✅🫀Health Monitoring
U.S. POINTER is the largest research commitment the Association has made in its history. The landmark results are testament to our commitment to our mission. Thank you to the study participants, our community, our donors, and the staff who made these findings possible.
alz.org/USPOINTERresults
World Dementia Council Trustee @alladi_suvarna co-chairs the Lightning Presentation Round on Cognitive Reserve And Resilience at #AAIC25. Presentations explore education, social factors & their impact on cognition. Research on these factors is important to understanding risk.
Join us in Toronto, Canada or online, July 27 - 31, for the @alzassociation’s #AAIC25! I'll be speaking on biomarkers and preclinical AD on July 27th and 31th. I hope to see you there at the world’s largest international conference on dementia research.
Curing Alzheimer’s disease requires a radically different approach. It’s time we embrace the complexity and think about systems rather than isolated pathologies. Read my latest opinion on this at @_TheTransmitterthetransmitter.org/alzheimer…
Great to see this work led by Destiny Berisha out! Happy to have co-authored this important work, which links hypoxemia during REM with regional white matter hyperintensities (WMH) and medial temporal lobe (MTL) structure.
@BryceMander@mike_yassa
Association of Hypoxemia Due to Obstructive Sleep Apnea With White Matter Hyperintensities and Temporal Lobe Changes in Older Adults
hubs.la/Q03p03p_0#NeuroX
Loved seeing my brain artwork being featured on @YassaLab’s thank you cards to their BEACoN study participants! Thanks @mike_yassa and #Liv for making these! ☺️
We’re thrilled to announce the publication of _Mysteries of the Social Brain_ by Drs. Bruce Miller & Virginia Sturm.
Explore human behavior & values through clinical stories. Discover how brain circuits influence empathy, altruism, morals & creativity.
amzn.to/4j9r3Fq
We are hiring!!!
The UCI ModelAD team is seeking a highly motivated Database Research Specialist with expertise in data integration and metadata harmonization to support large scale animal model and genomics research efforts.
Full position description: recruit.ap.uci.edu/JPF09537
1/9: Delighted to announce that our faculty cluster hire for the newly established Noel Drury, M.D. Institute for Translational Depression Discoveries at UC Irvine is now live. The submission deadline is April 9, 2025.