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Phagepapers @phagepapers

No longer active bot. Please join Bluesky instead. Too many Nazis about here. Used to be managed by @jamesrgurney

Joined October 2014
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271 Photos and videos
Structure of the siphophage neck-Tail complex suggests that conserved tail tip proteins facilitate receptor binding and tail assembly dlvr.it/T0G2gd

Structure of the siphophage neck-Tail complex suggests that conserved tail tip proteins facilitate...

Siphophages have a long, flexible, and noncontractile tail that connects to the capsid through a neck. The phage tail is essential for host cell recognition and virus-host cell interactions; moreov...

pubmed.ncbi.nlm.nih.gov
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Packing up the genome dlvr.it/T0G2gK

Packing up the genome - PubMed

Nucleotide and force-dependent mechanisms control how the viral genome of lambda bacteriophage is inserted into capsids.

pubmed.ncbi.nlm.nih.gov
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The mobilome of Lactobacillus crispatus M247 includes two novel genetic elements: Tn7088 coding for a putative bacteriocin and the siphovirus prophage ΦM247 dlvr.it/T0G2dM

The mobilome of Lactobacillus crispatus M247 includes two novel genetic elements: Tn 7088 coding...

Lactobacillus crispatus is a member of the vaginal and gastrointestinal human microbiota. Here we determined the complete genome sequence of the probiotic strain M247 combining Nanopore and Illumina...

pubmed.ncbi.nlm.nih.gov
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Freshwater Viral Metagenome Analyses Targeting dsDNA Viruses dlvr.it/T0DzQt
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Isolation and characterization of novel plasmid-dependent phages infecting bacteria carrying diverse conjugative plasmids dlvr.it/T0Dq9S

Isolation and characterization of novel plasmid-dependent phages infecting bacteria carrying...

This work was undertaken because plasmid-dependent phages can reduce the prevalence of conjugative plasmids and can be leveraged to prevent the acquisition and dissemination of ARGs by bacteria. The...

pubmed.ncbi.nlm.nih.gov
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DNA from non-viable bacteria biases diversity estimates in the corals Acropora loripes and Pocillopora acuta dlvr.it/T0Dq9R

DNA from non-viable bacteria biases diversity estimates in the corals Acropora loripes and Pocill...

Our study is highly relevant to microbiome studies on coral and other host organisms as it delivers a solution to excluding non-viable DNA in a complex community. These results provide novel insights...

pubmed.ncbi.nlm.nih.gov
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Enrichment, Sequencing, and Identification of DNA Bacteriophages from Fecal Samples dlvr.it/T0Dq8R

Enrichment, Sequencing, and Identification of DNA Bacteriophages from Fecal Samples - PubMed

Research on individual viruses and phages, as well as viral populations (viromes), is greatly expanding. Phages and viromes are increasingly suspected to have numerous impacts on the ecosystem in...

pubmed.ncbi.nlm.nih.gov
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The infant gut virome is associated with preschool asthma risk independently of bacteria dlvr.it/T0DctF

The infant gut virome is associated with preschool asthma risk independently of bacteria - PubMed

Bacteriophage (also known as phage) communities that inhabit the gut have a major effect on the structure and functioning of bacterial populations, but their roles and association with health and...

pubmed.ncbi.nlm.nih.gov
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Cas9 degradation in human cells using phage anti-CRISPR proteins dlvr.it/T0Dct7

Cas9 degradation in human cells using phage anti-CRISPR proteins - PubMed

Bacteriophages encode anti-CRISPR (Acr) proteins that inactivate CRISPR-Cas bacterial immune systems, allowing successful invasion, replication, and prophage integration. Acr proteins inhibit...

pubmed.ncbi.nlm.nih.gov
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Complete genome sequences and characteristics of mycobacteriophages Diminimus, Dulcita, Glaske16, and Koreni dlvr.it/T0Dcrc

Complete genome sequences and characteristics of mycobacteriophages Diminimus, Dulcita, Glaske16,...

Complete genome sequences of four novel mycobacteriophages, Diminimus, Dulcita, Glaske16, and Koreni, isolated from soil are presented. All these bacteriophages belong to subcluster M1, except Koreni...

pubmed.ncbi.nlm.nih.gov
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Observation of Bacteriophage Ultrastructure by Cryo-Electron Microscopy dlvr.it/T0DMVK

Observation of Bacteriophage Ultrastructure by Cryo-Electron Microscopy - PubMed

Transmission electron microscopy (TEM) is an ideal method to observe and determine the structure of bacteriophages. From early studies by negative staining to the present atomic structure models...

pubmed.ncbi.nlm.nih.gov
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Isolation of Bacteriophages for Clinically Relevant Bacteria dlvr.it/T0DMTn

Isolation of Bacteriophages for Clinically Relevant Bacteria - PubMed

The isolation of bacteriophages targeting most clinically relevant bacteria is reasonably straightforward as long as its targeted host does not have complex chemical, physical, and environmental...

pubmed.ncbi.nlm.nih.gov
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Anti-Bordetella bronchiseptica effects of targeted bacteriophages via microbiome and metabolic mediated mechanisms dlvr.it/T0DMSY

Anti-Bordetella bronchiseptica effects of targeted bacteriophages via microbiome and metabolic...

Bordetella bronchiseptica poses a significant challenge in the context of respiratory infections, particularly in weanling pigs. In this study, we investigated the impact of a novel targeted bacter...

pubmed.ncbi.nlm.nih.gov
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Guidelines to Compose an Ideal Bacteriophage Cocktail dlvr.it/T0CD5l

Guidelines to Compose an Ideal Bacteriophage Cocktail - PubMed

Properly designed bacteriophage therapeutics are the cornerstone for a successful outcome of bacteriophage therapy. Here we present an overview of the different strategies and steps that can be taken...

pubmed.ncbi.nlm.nih.gov
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Nano/microformulations for Bacteriophage Delivery dlvr.it/T0C1n9

Nano/microformulations for Bacteriophage Delivery - PubMed

Encapsulation methodologies allow the protection of bacteriophages for overcoming critical environmental conditions. Moreover, they improve the stability and the controlled delivery of bacteriophages...

pubmed.ncbi.nlm.nih.gov
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Bacteriophage Production in Compliance with Regulatory Requirements dlvr.it/T0C1mz

Bacteriophage Production in Compliance with Regulatory Requirements - PubMed

In this chapter, we discuss production requirements for therapeutic bacteriophage preparations. We review the current regulatory expectancies and focus on pragmatic production processes, implementing...

pubmed.ncbi.nlm.nih.gov
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Rapid Bench to Bedside Therapeutic Bacteriophage Production dlvr.it/T0C1lN

Rapid Bench to Bedside Therapeutic Bacteriophage Production - PubMed

It has been over 100 years since bacteriophages (phages) were used as a human therapeutic. Since then, phage production has dramatically evolved. Current phage preparations have fewer adverse effects...

pubmed.ncbi.nlm.nih.gov
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Use of Galleria mellonella as an Animal Model for Studying the Antimicrobial Activity of Bacteriophages with Potential Use in Phage Therapy dlvr.it/T0Blwd

Use of Galleria mellonella as an Animal Model for Studying the Antimicrobial Activity of Bacterio...

Interest in phage therapy has increased in the last decade, and animal models have become essential in this field. The larval stage of the wax moth, Galleria mellonella, represents an easy-to-handle...

pubmed.ncbi.nlm.nih.gov
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Studying Bacteriophage Efficacy Using a Zebrafish Model dlvr.it/T0BlwV

Studying Bacteriophage Efficacy Using a Zebrafish Model - PubMed

The rise of bacteria resistant to the antibiotics currently in use (multiple drug-resistant, MDR) is a serious problem for patients affected by infections. This situation is even more worrying in the...

pubmed.ncbi.nlm.nih.gov
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Bacteriophage Control of Infectious Biofilms dlvr.it/T0BlwG
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