We develop and employ high-resolution methods to study Biology where it happens: In Cells
Joined December 2018
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49 Photos and videos
6 Dec 2023
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17 Oct 2023
Just a quick update. Everyone in the lab has been brought to safety. All internationals are evacuated. We regroup online to move forward. We'll be back! 🇮🇱
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8 Oct 2023
These are hard times. We feel your sorrow and we share your grieve. We shall stand strong together! 🇮🇱
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24 Jul 2023
Today is the day. A copy of Israel's Declaration of Independence (in lieu of a formal Constitution) towering over the institute.
24 Jul 2023
“Everything that is really great and inspiring is created by the individual who can labor in freedom” (Albert Einstein)
Photo by Gilad First
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24 Jul 2023
".. until the establishment of the elected, regular authorities of the State in accordance with the Constitution which shall be adopted by the Elected Constituent Assembly not later than the 1st October 1948." This never happened.
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1 Jul 2023
This was a panel discussion on the future of Structural Biology. Age of participants: KW 84, JF 83, JD 79, HM 74. Moderator WL 74. Any question? science.org/content/article/…
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26 Jun 2023
Who is going to lead the way? More such efforts are needed. The future of Structural Biology is in the cell!
23 Jun 2023
Great to see Philipp Selenko from @WeizmannScience highlighting our @wellcometrust cellular structural biology DTP as an exemplar for the future needs of cellular bioimaging at the @iNEXT_Discovery user meeting in Budapest #bioimaging
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23 Jun 2023
Fun facts about the Physics of Biology … but indulge with caution > numbers likely represent boundary limits as they predate (some of the more) modern concepts and quantifications. But you get the point; Cells are amazing!
22 Jun 2023
Cells are very fast and crowded places.
A molecule of glucose flies through a cell at 250 mph.
A protein tumbles 60 million times per minute.
These numbers seem made up. How did we figure this stuff out?
ALT Acknowledgement: Martina Maritan, Ludovic Autin, David S. Goodsell, Scripps Research and RCSB Protein Data Bank. doi: 10.2210/rcsb_pdb/goodsell-gallery-040
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12 Jun 2023
Exciting times for Cellular Structural Biology! Mark this announcement👇
12 Jun 2023
In collaboration with the @rbolab, we are pleased to present AlphaLink2 - a modified version of AlphaFold-Multimer that is capable of directly incorporating experimental residue-residue contact data from crosslinking MS (and potentially other techniques as well). (1/7)
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23 Mar 2023
Also elsewhere …
23 Mar 2023
The president and rector of the Hebrew University, as well as the deans, at the head of the demonstration!!
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23 Mar 2023
President and Vice President … this is what strong leadership & good governance looks like
23 Mar 2023
@WeizmannScience president Alon Chen and VP Ziv Reich out to demonstrate in support of arrested scientist @ShikmaBressler
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6 Dec 2022
Yet another visual reminder of how tensely packed the (bacterial) cytoplasm really is. An impediment to biological fidelity? Far from it. Cellular confinement > probably THE biggest success story in evolution.
5 Dec 2022
I can now load _basically_ every atom from an entire bacterial cell, into #blender3d and #geometrynodes via #molecularnodes. Each macromolecule is down to atomic detail where available via CellPack, totalling ~250,000,000 points, all rendering (quite quickly) in Cycles #b3d
ALT A 3D rendering of the inside of a Mycoplasma Genitaliam cell, which has been vertically sliced to show the proteins and DNA that are inside the cell. The sliced cell is on a pink background with soft lighting, and it floats atop a reflective surface.
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5 Dec 2022
While many may think that I reviewed this MS (especially if you read the reviewers' comments) ... I didn't. If I had, I'd done it differently. IMO, a lot in this paper is beside the point 🤷♂️
3 Dec 2022
An improved method for in-cell NMR is developed using a reporter to evaluate protein delivery and delivery parameters to different cell lines and applied to IDPs and folded proteins including structure determination of GB1 at 1.1 Å resolution.
nature.com/articles/s42003-0…
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