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The Prisner EPR Group @prisnerlab

Our research is on EPR spectroscopy, new state-of-the-art experimental, technical developments of EPR methods and new EPR applications on biological systems

Joined November 2018
  • Tweets 27
  • Following 24
  • Followers 359
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we published 'Non-Covalent Spin-Labeling of RNA With Short Hairpins Containing the Rigid Spin Label Çm' in ChemEurJ: doi.org/10.1002/chem.2025032…

Non‐Covalent Spin‐Labeling of RNA With Short Hairpins Containing the Rigid Spin Label Çm

Incorporation of sophisticated spectroscopic probes into RNA often requires an extensive synthetic effort. To minimize that, a noncovalent spin-labeling strategy using spin-labeled hairpins has been...

chemistry-europe.onlinelibrary.wiley.com
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We published 'Optimized shaped pulses for 2D-SIFTER' by Paul Trenkler, Burkhard Endeward, Snorri Sigurdsson, and Thomas Prisner: doi.org/10.5194/mr-2025-11 It's open for comments.
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We published: Using PELDOR to count spins on multi-nitroxides. It is free to download (for 90days) doi.org/10.1016/j.jmr.2025.1…
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Just if you like to deep into data, the link to the repository misses a '=': dx.doi.org/10.25716/gude.1fc…
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Structure and internal dynamics of short RNA duplexes determined by a combination of pulsed EPR methods and MD simulations - Gauger - Angewandte Chemie International Edition - Wiley Online Library onlinelibrary.wiley.com/doi/…

Structure and Internal Dynamics of Short RNA Duplexes Determined by a Combination of Pulsed EPR...

We combined orientation-selective PELDOR and 19F Mims ENDOR to characterize the structural ensemble of RNA duplexes and their internal motions. In a quantitative comparison to MD simulations of RNA...

onlinelibrary.wiley.com
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Just for the rest of you, we (Hetzke, T., Vogel, M., Halbritter, A.- L. J., Saha, S., Suess, B., Sigurdsson, S. Th. and Prisner, T. F.) published a paper on PELDOR on RNA with Mn(II) Spin-labels: pubs.acs.org/doi/full/10.102…

Simultaneous Localization of Two High Affinity Divalent Metal Ion Binding Sites in the Tetracycline...

Mg2 ions play an essential part in stabilizing the tertiary structure of nucleic acids. While the importance of these ions is well documented, their localization and elucidation of their role in the...

pubs.acs.org
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Solid-Effect Dynamic Nuclear Polarization in Viscous Liquids at 9.4 T Using Narrow-Line Polarizing Agents by A.A. Kuzhelev, et. all. published in JACS doi.org/10.1021/jacs.3c01358

Solid-Effect Dynamic Nuclear Polarization in Viscous Liquids at 9.4 T Using Narrow-Line Polarizing...

Dynamic nuclear polarization (DNP) is a hyperpolarization method that is widely used for increasing the sensitivity of nuclear magnetic resonance (NMR) experiments. DNP is efficient in solid-state...

pubs.acs.org
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Free access to our review (until June 27.) authors.elsevier.com/c/1h2Qm…

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Implementation and Applications of shaped pulses in EPR by B. Endeward, M. Bretschneider, P. Trenkler and T.F. Prisner in Progress in Nuclear Magnetic Resonance Spectroscopy: doi.org/10.1016/j.pnmrs.2023…
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Professor (W3) of Physical Chemistry (Magnetic Resonance with focus on EPR Spectroscopy) job with Johann Wolfgang Goethe-Universität Frankfurt Campus Riedberg, 60438 Frankfurt nature.com/naturecareers/job… #jobs

Professor (W3) of Physical Chemistry (Magnetic Resonance with focus on EPR Spectroscopy) - Campus...

Goethe University Frankfurt am Main invites applications for the position of   Professor (W3) of Physical Chemistry (Magnetic Resonance with focus ...

nature.com
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Denysenkov, V., Dai, D. and Prisner, T. F. (2022), A triple resonance (e, 1H, 13C) probehead for liquid-state DNP experiments at 9.4 Tesla. J. Magn. Reson. 337, 107185: doi.org/10.1016/j.jmr.2022.1…
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Long-range distance determination in fully deuterated RNA with pulsed EPR spectroscopy by B. Endeward, Y. Hu, G. Bai, G. Liu, T. Prisner & X. Fang in Biophysical J.: authors.elsevier.com/c/1eHYA…
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Increased flow rate of hyperpolarized aqueous solution for dynamic nuclear polarization-enhanced magn. reso. imaging achieved by an open Fabry–Pérot type microwave resonator by A. Fedotov, I. Kurakin, S. Fischer, T. Vogl, T. F. Prisner & V. Denysenkov: doi.org/10.5194/mr-1-275-202…

Increased flow rate of hyperpolarized aqueous solution for dynamic nuclear polarization-enhanced...

Abstract. A continuous flow dynamic nuclear polarization (DNP) employing the Overhauser effect at ambient temperatures can be used among other methods to increase sensitivity of magnetic resonance...

mr.copernicus.org
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Thermodynamic Basis for Conformational Coupling in an ATP-Binding Cassette Exporter by K. Barth, M. Rudolph, T. Diederichs, T.F. Prisner, R. Tampé and B. Joseph, J. Phys. Chem. Lett. 2020, 11, 19, 7946–7953 doi.org/10.1021/acs.jpclett.…

Thermodynamic Basis for Conformational Coupling in an ATP-Binding Cassette Exporter

ATP-binding cassette (ABC) transporters constitute one of the largest protein superfamilies, and they mediate the transport of diverse substrates across the membrane. The molecular mechanism for...

pubs.acs.org
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Compaction of RNA duplexes in the cell by Alberto Collauto, Sören von Bülow,Dnyaneshwar Gophane, Subham Saha, Lukas Stelzl, Gerhard Hummer, Snorri Th. Sigurdsson, Thomas Prisner doi.org/10.1002/anie.2020098…
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Multiquantum Counting of Trityl Radicals by M. Bretschneider, P.E. Spindler, O.Y. Rogozhnikova, D.V. Trukhin, B. Endeward, A.A. Kuzhelev, E. Bagryanskaya, V. Tormyshev and T. F. Prisner, J. Phys. Chem. Lett. 2020, 11, 15, 6286–6290 doi.org/10.1021/acs.jpclett.…
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Season's Greetings to all of you!
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High-resolution EPR distance measurements on RNA and DNA with the non-covalent G´ spin label by Marcel Heinz, Nicole Erlenbach, Lukas S Stelzl, Grace Thierolf, Nilesh R Kamble, Snorri T H Sigurdsson, Thomas F Prisner, Gerhard Hummer doi.org/10.1093/nar/gkz1096
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Shaping EPR: Phase and amplitude modulated microwave pulses by Thomas Prisner is now online and free to download (for a short time): authors.elsevier.com/a/1ZaHq…
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Binding of tetracycline to its aptamer determined by 2D-correlated Mn2 hyperfine spectroscopy by Thilo Hetzke, Alice M.Bowen, Marc Vogel, Maximilian Gauger, Beatrix Suess &Thomas F.Prisner authors.elsevier.com/a/1YzEz…
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