Joined March 2017
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- Followers 649
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108 Photos and videos
Latest #CASP17 #RNA targets are a tiny aptamer for tryptophan selected by Yarus lab @cuboulder, a miniTTR by RNAmake @JosephYesselman, and two singlet glycine riboswitches discovered by @ronbreaker Strobel. Note that first one β a 25-nt RNA by #cryoEM? predictioncenter.org/casp17/β¦
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The 17th Critical Assessment of Structure Prediction #CASP17 begins tomorrow. 2 #RNA targets per day for next few weeks! >60 servers registered already, including @kaggle teams. Join the fun at predictioncenter.org/casp17/
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RT @MarvinBeaverman: I would like to thank Beaver Nation on the continental USA and around the world for your love and support. Go Beavs π¦«β¦
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π³ππππ π° π·ππππππ‘ retweeted
Apr 10
A Nanopore ultralong run we just did for Hop! Nearly 110Gb off a single flow cell with the true N50 probably >70Kb. Very excited for this one ππ§¬
#ONT
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π³ππππ π° π·ππππππ‘ retweeted
somebody said in this age of agentic AI its become easier to write papers.. I don't think it's true (for me). It's become harder... maybe I am doing it wrong. I am seriously worried about AI slop and halucinations.
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What does Paul McCartney say when making the first cut of a pecan pie?
π΅ "Simply halving a wonderful Christmas pie" π΅
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Every year @OregonState at the start of Fall quarter, we are greeted by a beautiful Fall Equinox sunset #BeaverHenge
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π³ππππ π° π·ππππππ‘ retweeted
28 Aug 2025
Received two reviews on a paper I am a co-author on that was submitted the @NaturePortfolio Scientific Reports. Both reviews were written by ChatGPT & clearly not edited with hallucinations. Shame on the editors for letting this unethical AI slop out the door.
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π³ππππ π° π·ππππππ‘ retweeted
We are excited to share a new publication w/ @JosephYesselman in @NAR_Open. RNA secondary structure prediction and design typically minimize the global free energy. We show that *local* stability compensation is a powerful RNA design approach 1/4
academic.oup.com/nar/articleβ¦
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We are excited to share a new publication w/ @JosephYesselman in @NAR_Open. RNA secondary structure prediction and design typically minimize the global free energy. We show that *local* stability compensation is a powerful RNA design approach 1/4
academic.oup.com/nar/articleβ¦
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Our large design libraries demonstrate that local stability compensation (net free energy of local substructure) correlates with folding accuracy through a Hill equation relationship. 3/4
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Local Stability Compensation presents a bottom-up approach to RNA design, focusing on local interactions, compared to the top-down approach of global free energy minimization. Check out the paper for more! 4/4
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We are excited to share our latest publication, bpRNA-CosMoS, a k-mer based measure of #RNA structural similarity. This method allows us to perform millions of structural comparisons for clustering in a short amount of time. #OpenAccess in #Bioinformatics
academic.oup.com/bioinformatβ¦
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Although it isn't as accurate as our other alignment-based method bpRNA-align, (Published in RNA) it allows us to perform an initial clustering of 100s of thousands of structures, which we can refine, reducing the overall number of calculations
rnajournal.cshlp.org/contentβ¦
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We hope to apply these methods to identify novel structures and to improve our RNA secondary structure meta-database, stay tuned for bpRNA-hub.
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π³ππππ π° π·ππππππ‘ retweeted
25 Mar 2025
.@ProfHendrix photographed this literal ray of spring equinox light shining through the skybridge connecting Cordley Hall and the Agriculture & Life Sciences Building. Itβs a phenomenon heβs dubbed βBeaverHengeβ because it only happens during the equinox. π¦«β¨
Happy spring!
ALT Sun shining and refracting through a skybridge between two brick buildings on a college campus.
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I caught a ray of light through the sky bridge between Ag & Life Sciences and Cordley Hall tonight around 7pm. Although the equinox was two days ago, it still works. It was the first day this week that wasn't too cloudy to see anything @oregonstate.edu #beaverhenge #gobeavs!
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