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ISPT_ProteinTermini @proteintermini

International Society of Protein Termini (ISPT), we have a shared interest in protein terminal modifications and their downstream effects on protein function.

Joined January 2019
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ISPT_ProteinTermini@proteintermini
11 Sep 2024
As we conclude this inspiring conference, we extend our heartfelt thanks to all the speakers, organizers, and participants for their invaluable contributions. See you all in Palermo for the next one. #proteintermini24
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ISPT_ProteinTermini retweeted
Huanglab@rhuanglab
17 Sep 2024
Our recent publication led by Ying Meng @Purdue_MCMP explores how NTMT1-mediated Na-methylation affects the stability and interaction of PAD1, offering insights into protein N-terminal methylation. Great contributions on proteomics by Wang lab at UCR. pubs.acs.org/doi/full/10.102…

Characterizations of Protein Arginine Deiminase 1 as a Substrate of NTMT1: Implications of Nα-Met...

α-N-Methylation (Nα-methylation), catalyzed by protein N-terminal methyltransferases (NTMTs), constitutes a crucial post-translational modification involving the transfer of a methyl group from...

pubs.acs.org
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As we conclude this inspiring conference, we extend our heartfelt thanks to all the speakers, organizers, and participants for their invaluable contributions. See you all in Palermo for the next one. #proteintermini24
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And last, a quick shoutout to the (almost) full organizing team: @emily_flashman, @Fra_LicO2si and both of their groups! As always, better together. #proteintermini24
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Frederica Theodoulou@freddietheodou1
12 Sep 2024
Just back from an excellent @proteintermini meeting in Oxford. Lovely to catch up with #proteostasis friends and hear about the latest results. Big thanks to @emily_flashman, @Fra_LicO2si and the team for organising 👏
ISPT_ProteinTermini@proteintermini
11 Sep 2024
As we conclude this inspiring conference, we extend our heartfelt thanks to all the speakers, organizers, and participants for their invaluable contributions. See you all in Palermo for the next one. #proteintermini24
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Congratulations to the winners of the best Poster prize - Samuel Zolg, Dani Amat and Anna Dirr. Best talk - Mahima Bhat. #proteintermini24
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Final talk of the session and the meeting, Daniel Youngjae Park (Seoul National University) presents ‘Targeted Protein Degradation as a Novel Therapeutic Approach Against Amyotrophic Lateral Sclerosis (ALS)’. #proteintermini24
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Thierry Meinnel (Université Paris-Saclay) presents his work on ‘Novel, tightly structurally related N-myristoyltransferase inhibitors with potent yet distinct inhibitory mechanisms’. #proteintermini24
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Next up, elevator pitch by Hye Yeon Kim on ‘A novel small-molecule AUTOTAC that selectively degrades pathological tau aggregates and improves outcomes in Alzheimer’s disease’. #proteintermini24
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After some excellent work from Yong Tae Kwon, it is now time to hand over the baton to Carmela Giglione @Giglionelab as new leader of the ISPT! Carmela will also be the host of the next ISPT conference in the sunny Palermo (June 2026)! Stay tuned 🎉 #proteintermini24
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Next up: Jihoon Lee discusses ‘Targeted degradation of α-synuclein aggregates in Parkinson’s disease via the AUTOTAC chemical platform’. #proteintermini24
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The terminal session of the protein termini meeting kicks off with Emmanuelle Graciet, diving into ‘The N-degron pathway’s role in the crosstalk between hypoxia signaling and plant immunity’. #proteintermini24
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Last talk before the break, Mikie Kukwikila from Oxford Nanopore on new advances in protein sequencing. #proteintermini24
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Next up, Ron Huang talking about new inhibitors for human N-terminal Methyltransferases. #proteintermini24
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Elevator pitch time! First of the day is Rebecca Latter on ‘Modulation of Arabidopsis thaliana Plant Cysteine Oxidase 4 (AtPCO4) activity’. #proteintermini24
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First scientific talk of the day, Beatrice Giuntoli sharing some new insights on substrate discovery for plant Cys N-degron pathway. #proteintermini24
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Starting off the last day with some talks from @FEBSnews representatives Matera Mancek Keber and Duncan Wright. #proteintermini24
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After a fruitful day of science! Conference dinner at Wadham College. #proteintermini24
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Today's last (flash) talk, Samuel Madden, will tell us about "Plant Cysteine Oxidase (PCO) Oxygen -Sensing Function Is Conserved in Unicellular Algae" #proteintermini24
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Next, all the way from Seoul, we will hear from Min Ju Lee, presenting "Degradation of melanosome/melanin and chemical modulation of melanophagy by the N-degron pathway via p62/SQSTM1-dependent macroautophagy". #proteintermini24
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Janet Kumita, coming from Cambridge, is next. She will tell us about "The impact of N-terminally acetylated α-synuclein on designing therapeutic strategies to combat Parkinson’s Disease" #proteintermini24
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