Embarking on a journey to bring cutting-edge #psychedelic #science to the public in the most accessible, thorough and scientifically accurate way possible.
Using validated behavior models and known standards, studies are finding significant differences between male and female rodents given psychedelic drugs.
Norpsilocin is not psychoactive but minor changes to its chemical structure translate into major changes in its pharmacology.
Magic mushroom science marches on as understudied psilocybin derivatives start taking center stage.
Lab grown brains help to shed insight on 5-MeO-DMT mechanisms.
The serotonin receptor subtype 5-HT2A is key for the effects of many psychedelic substances in humans, but it is also a major drug target for new antidepressants. However…
A recent study found that Single Nucleotide Polymorphisms (SNPs) in the 5-HT2AR gene may impact the effects of clinically relevant psychedelics. This research implies that patients carrying certain…
Psychedelic drugs like psilocybin and LSD have been investigated for their anti-anxiety (anxiolytic) potential in people with end-of-life anxiety associated with severe illness…
Despite excessive fear surrounding anecdotal reports of psychedelics inducing suicidal behaviors dating back to the 1950s, the current scientific landscape suggests potential therapeutic utility.
Psilocybin demonstrated preliminary efficacy for alcohol use disorder in a recent randomized clinical trial. The mechanism may lie in its interaction with glutamate receptors in the reward pathway of…
Dr. Alex Kwan shares his insight on the field of preclinical psychedelic research and where he thinks things are headed in the future – in his lab, in drug discovery, and beyond.