"Innate Targaryen Madness" is when a woman is given leadership and suddenly goes insane because females aren't fit to rule. Congrats, House of the Dragon, for turning "Sexism destroyed the kingdoms and made dragons go extinct. No More Queens" to "What if Misogyny is Right?"
emma d’arcy says rhaenyra’s “innate targaryen madness” is no longer being held back in season 3:
“In season one, Rhaenyra was plagued by doubt: she questioned her right to rule, what kind of ruler she should be, and whether her father was even right to name her heir in the first place. […] I think this growing fanaticism does indicate a marked changed in character. For the first two seasons, doubt kept her innate Targaryen madness in check - by season 3, that moderating force has fallen away.”