Joined May 2011
- Tweets 4,586
- Following 1,898
- Followers 1,050
- Likes 13,909
141 Photos and videos
If you're based in NH consider coming to "AI Pill NH"
luma.com/q0rqu57n?tk=NWbxgL
Claude/OpenAI/Grok/MCP/Openclaw working session.
We need more "computer user groups" :)
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Jun 12
Yes please
Jun 11
1/ There's nothing more un-American than our slow, often corrupt build-by-permission permitting regimes.
With AI creating an even wider gap between how the world works, and how it could work — it's time for radical change.
@judgeglock & I make the case for private permitting 🧵
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May 30
A friend who works in the sound contractor industry as a labor/job aggregator told me how he's building his own bespoke CRM for his exact needs.
He used a term "code soak". I'd never heard that term used before. But then I'm not formally trained in software. (but even moreso neither is he!)
He learned it from an LLM.
This feels like some evidence that LLM's are going to actually expand the knowledge of the median human immensely and fast.
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Ryan retweeted
May 27
We’ve just launched an online community for paying subscribers called Free Press Forum.
Check it out: TheFP.com/forum
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May 26
Beautiful.
I think these folks are starting something special!
❤️
May 26
You came for the journalism. You stayed for the community.
Today, we’re launching something new: The Free Press Community—including a Supper Club, Retreat, digital Forum, and more, all designed to bring independent minds together online and in real life.
Think for yourself, not by yourself.
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May 22
This is so unfortunate.
May 22
Coos Senator Rochefort is fine watching his constituents die of cancer, but fine if their kids get gender surgery without informing the parents. He needs to go, and we are hearing that he will be primaried.
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Ryan retweeted
The NH Senate has again rejected Right to Try, shutting the door on patients seeking experimental treatments. A few state senators have decided that New Hampshire is closed for business to biotech firms offering frontier therapies.
Here's what happened and our next steps.
This term, a bipartisan majority of the state House passed HB 1734 and HB 1735: two bills to make New Hampshire the best state in America for experimental therapies. The bills were based largely on existing laws in Montana and Florida.
Granite Bio Innovation—and the businesses and patients we support—helped build a coalition across every branch of elected state government to support these bills. We also worked for several months to build consensus in the Senate. Senators received calls from patients, businesses, investors, scientists, and healthcare providers supporting the bills.
After Senator David Rochefort requested a long list of changes to HB 1734, the biotech firms involved agreed to every change. But these negotiations were not in good faith. Senator Rochefort abruptly decided he would not accept any version of the bills, and the Senate rejected both.
The New Hampshire House then attached both bills to Senate Bill 504—this time with an even broader bipartisan vote of 197 to 145. Rather than negotiate a compromise, the Senate decided to fight this bill at any cost.
Sadly, there is no pathway for making New Hampshire a commercial-scale hub for experimental therapies until the composition of the NH Senate changes.
Until then, Granite Bio Innovation will continue to support New Hampshire's patients and innovators in the following ways:
• Shaping other areas of state legislation in a way that facilitates frontier biotechnology in New Hampshire.
• Advocating for state and federal regulatory policy that allows New Hampshire's biotech ecosystem to flourish.
• Serving as a nexus for innovators and pro-biotech policymakers, including through an annual conference in August and by providing resources to healthcare providers.
We are grateful to the many New Hampshire officials who have embraced the state's promise as a biotech hub, including @NHHouseGOP leadership, Governor @KellyAyotte, Mayor @JayRuais, and those senators who supported Right to Try on the Senate floor.
We are especially grateful to @NHSpeaker for sponsoring the amendment to SB 504 and to Representatives @KesselringSteve and @cole4nh for their tireless leadership on these bills and courageous stand for patients in need.
With a biotech revolution approaching, a US state will soon become a hub for experimental therapies. The only question now is which one.
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May 20
We're open for business in NH.
LFG
Thank you @KellyAyotte
Thank you, @KellyAyotte, for standing for patients.
New Hampshire is ideally positioned to become the best state in the US for frontier biotech.
When SB 504 passes, we are ready to work hard to make emerging therapies a key part of the New Hampshire advantage.
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May 14
Thank you to @NHHouseGOP
This is the right choice.
Now let's see if @NHSenateGOP knows the right choice.
The New Hampshire House has again voted in favor of HB 1734 and HB 1735 - two bills to make New Hampshire a hub for experimental therapies.
SB 504 was amended to include both bills and then passed the House 197-145, this time picking up several Democrats.
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Ryan retweeted
A New Hampshire Senate committee has voted to block patients from accessing experimental treatments. Now is the time to call your state senator and stand for patients.
New Hampshire patients deserve the right to try cutting-edge therapies without waiting on Washington. Two bills now before the NH Senate, HB 1734 and HB 1735, would create a solid pathway for emerging treatments here in NH.
Both bills cleared the NH House with the support of every House Republican and some Democrats. But on May 6, the Senate HHS Committee voted to send the bills to "Interim Study" — a way of killing the bills. The full Senate will hear the bills on Thursday, May 14.
Follow the link below to call your state senator now. Tell your senator to vote NO on Interim Study and YES on HB 1734 and HB 1735.
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May 9
What the hell happened to this country.
May 8
I have a patient with glioblastoma who got halfway through a clinical trial and was seeing great results, only to have his treatment ceased when the trial stopped.
He then spent $10,000 of his own money trying to use Expanded Access, and was denied.
Now, accessing treatment through Montana's SB535 is his last hope. There are biotechs and manufacturers willing to provide treatment, but only if we can get guarantees they won't be punished by @US_FDA for doing so.
I'll be in Washington D.C. with him on the 19th and 20th of this month, if anyone reading this would like to help, please tag your Senator and House Rep and ask them to make some time to meet with us.
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May 6
FDA is too slow.
HB1734 provides a framework for experimental clinics to deliver results AND data sooner!
This should be an obvious one for the "Live Free or Die" state.
LFG. Come on now!
New Hampshire’s Right to Try bills, HB 1734 and HB 1735, faced a setback today when the Senate HHS Committee voted against both bills. These bills will make NH the best state in America for emerging therapies—drawing on successful laws already passed in Montana and other states.
While both Senate Democrats opposed the bills, Republicans on the committee were divided—with GOP Senators Regina Birdsell and Dan Innis both indicating they were prepared to support the bills.
We remain optimistic. These bills earned the votes of every single Republican and some Democrats in the New Hampshire House. Elected leaders know that these bills will help patients and expand the New Hampshire Advantage.
We believe both bills will pass this month—we’ll just have to take the long way to get there. Learn more and take action below.
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Apr 25
This threatens top tier cities' nexus status.
Can't wait to see how this unfolds!
Apr 25
Whoah, self-driving cars compete with airlines. I never considered that till now.
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Ryan retweeted
NH can transform lives by passing HB 1734 and 1735, making us the best state in the US for emerging biotech.
But the medical establishment doesn't want innovative treatments cutting into their profits. These bills needs your voice today. granitebio.org/legislation
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Apr 15
hey folks at @NotionHQ
Context is king.
The more context I give my open claw, the better it does.
My application db
My sales crm (which will just be notion eventually)
My help center
My slack history
many other things
=
better context
Better context LLM
is better than
Product Native Agents
I think the direction you're going with Notion Native Agents is a mistake. :-| 🙏
Figure out how to make notion even easier and more obvious to use for agents that will be run in-house.
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Apr 13
NH on how we design policy for the 21st century...
Instead of "tax the rich" simps surrounding us.
Thanks for your leadership @KeithAmmon !
The Sovereign Stack: Energy, Compute, and Sound Money as State Policy with Rep. Keith Ammon
Representative Keith Ammon (@RepKeithAmmon) introduces his “Sovereign Stack” concept, arguing that true individual sovereignty depends on control over three key layers: energy, computing, and sound money. He highlights New Hampshire’s push for policies like decentralized energy, advanced nuclear, Bitcoin reserves, and legal frameworks for DAOs to strengthen independence and innovation. Ammon emphasizes the growing importance of computational power and AI, warning that states that control compute will shape the future, while advocating for “computational freedom” and pro-tech legislation. He concludes that advancing liberty through these systems will drive prosperity, framing sovereignty as something actively built through policy and technology.
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Apr 10
Come and get a cookbook!
:-)
Apr 10
I think most creators are playing the wrong game.
They’re trying to go global — chasing reach, virality, and followers they’ll never meet.
Meanwhile, some of the most interesting @beehiiv creators are doing the opposite.
They’re going local.
Building a few thousand subscribers in a single city.
Actually knowing their audience.
Turning that into real-world experiences — and real revenue.
We’ve seen creators:
– monetize with local sponsors
– host events that sell out
– build communities that actually show up
It’s a different playbook.
@getdnnr has partnered with @beehiiv to break it down into something practical:
The Local Newsletter Monetization Cookbook 😋
It’s a look at how a small group of creators are turning local audiences into real businesses — without needing to go viral.
Featuring real revenue numbers from Brian Skinner, Landon Huslig, Nick Hageman, Sam Harper. It lights a path to cracking $100k in annual revenue, all from your local audience.
If you’re building a newsletter, I’d spend 10 minutes on this.
👉 Comment COOKBOOK and I'll DM you the link!
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