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@scholpplab.bsky.social @scholpp_lab

This account is closed. Bye, bye, Twitter. Discuss science with us in a friendly atmosphere here: @scholpplab.bsky.social

Joined June 2012
  • Tweets 1,037
  • Following 2,260
  • Followers 1,168
233 Photos and videos
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@scholpplab.bsky.social@scholpp_lab
20 Dec 2023
Our work reveals that in zebrafish embryos, Wnt5b and Ror2 are transported via cytonemes to initiate Wnt-PCP signaling, challenging traditional views on cellular responsiveness based solely on receptor expression nature.com/articles/s41586-0… @UK_Wnt @LSI_Exeter

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Happy New Year! I hope 2025 is good for you all. We start this year with a somewhat controversial review. sciencedirect.com/science/ar…. Here, we discuss how a cell receives signalling receptors from neighbouring cells, allowing them to transduce a previously unknown signal. 1/3
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This idea has significant implications because cells not expressing a specific receptor can still transduce the signal. Cytonemes facilitate the exchange of receptors. This idea extends our concept of competence and adds a new level of cellular plasticity. 3/3.
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This ability to react is transient (until receptor degradation). We refer to such a feature as "adoptive competence" - in contrast to Waddington's "innate" competence to transduce a specific signal. Translated to Emil Fischer’s concept of “key and lock”. 2/3
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Save the date! First Zebrafish meeting in the UK. 10 - 12. September 2025 in Exeter. @eu_fish @InfoIzfs
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That is a big blow for Twitter. We did the transition yesterday. You can find us (and a supportive, open and scientifically interested community) on BlueSky: @scholpplab.blsky.social
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Bluesky is currently the #1 free app on the Top charts 🔵 Twitter (X) is no longer in the top 25! You will find us @scholpplab.bsky.social like all the other cell/dev bios.
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Ops, we just moved to bluesky as well. @scholpplab.bsky.social Happy days!
Peter Walentek@WalentekLab
11 Nov 2024
Seems like there is some serious momentum many months after I set up a profile there... If you're looking for me there use this bsky.app/profile/walenteklab…
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@scholpplab.bsky.social retweeted
Peter Walentek@WalentekLab
11 Nov 2024
Seems like there is some serious momentum many months after I set up a profile there... If you're looking for me there use this bsky.app/profile/walenteklab…
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Congrats to Dr. Gemma. What an excellent day for a viva. You did a brilliant job! A special thank-you to Tanya Whitfield @TTWhitfield @uni_sheffield, who made it a great experience for Gemma. And thanks to Soojin and Nic to act as internal examiners. @LSI_Exeter
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.... I am happy to tell you that your manuscript has been accepted for publication ... Oh, happy days! 😀
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And one other thing for all zebbie folks….
@scholpplab.bsky.social@scholpp_lab
31 Oct 2024
What an excellent day @lifesciencebath @bathuni. Thanks to @bssrnk and @phil1pingham for hosting me. And what a great surprise that @stefarber joined. @LSI_Exeter
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What an excellent day @lifesciencebath @bathuni. Thanks to @bssrnk and @phil1pingham for hosting me. And what a great surprise that @stefarber joined. @LSI_Exeter
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On my way to @lifesciencebath @UniofBath . Last changes to my presentation and checking the CV of my host 😆. @phil1pingham see you soon, Phil! @LSI_Exeter #cytoneme rocks!
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Congratulations to "Dr" Kevin for a successful PhD viva on Ror2 signalling in synaptogenesis in AD. Thanks to examiners Dr Nik and Prof Michael for a great viva. @LSI_Exeter
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Excellent reunion of the cytoneme group with ⁦@dmvirshup⁩ and ⁦@lab_ogden⁩ at #Wnt2024 in ⁦@UniHeidelberg⁩ @dkfz. Contact-mediated signalling is crucial for Wnt and Shh, and we progress in zebrafish, mice and human organoids.
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And another fantastic presentation from a WntUK founding member @VivianLiLab on Sox2 function in reprogramming. Wnt research rocks in the UK. #Wnt2024 @UK_Wnt
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Hope to see many of you at the WntUK meeting in Oxford next year.
Wnt UK@UK_Wnt
26 Sep 2024
Replying to @UK_Wnt
….. and a great plug for our @OxfordCancer sponsored WntUK meeting next year at @WorcCollegeOx @UniofOxford March 24th 2025.
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Fantastic presentation from Sntonia Schubert from the @Boutroslab on Dvl2 condensate. And yes, they correlate with signal activation. Lots of discussion #Wnt2024 @wntuk2023164
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Excellent talk by ⁦@wntlab⁩ about membranous vs nuclear location of β-catenin #wnt2024 ⁦@wntuk2023164⁩
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Back in Heidelberg and walking down memory lane. #wnt2024 @DKFZ @LSI_Exeter
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