Acta Neuropsychiatrica is an international journal focusing on translational neuropsychiatry. We publish high-quality original research papers and reviews.

Joined August 2015
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Acta Neuropsychiatrica will keep actively contributing to sharing #science & disseminating accurate information in all platforms. If you are migrating, make sure you find our handles: @🦋actaneuropsych 📷ActaNeuropsychiatrica #neuropsychopharmacology #Psychiatry #sciencetwitter
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A 25-year longitudinal birth cohort study from Estonia reveals how genes, biomarkers, environment, and family shape behavior, mental health, and life trajectories. Findings offer key insights into neurodevelopment, psychiatric risk!
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Some papers carry more than scientific weight: they carry legacy. This study honors a deeply respected contributor to Acta Neuropsychiatrica and a leading figure in psychiatry, whose impact continues to shape the field.
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Authors also explore the mechanistic basis of these effects, including receptor interactions. The review points to a compelling possibility: that ibogaine’s therapeutic value may extend beyond symptom relief to supporting neural repair. doi.org/10.1017/neu.2026.100…
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We remember with admiration Dr. Stein behind this contribution, whose work and generosity helped advance not only science, but the psychopharmacology community. A lasting contribution and a meaningful legacy.
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How effective are music-based interventions for mental health in young adults? In this systematic review of clin trials in young adults, found that music therapy, binaural beats & rhythm-based auditory stimulation are associated w/ moderate improvements across multiple domains:
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– Anxiety and mood regulation – Sleep quality – Stress-related physiological markers – Cognitive performance Effect sizes indicate clinically meaningful, though not large effects.
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These non-pharmacological, technology-delivered approaches offer accessible support and align with young adults' lifestyle. A promising step toward scalable mental health support. Check the study for more info: doi.org/10.1017/neu.2026.100…
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Acta Neuropsychiatrica retweeted
The latest perspective on ibogaine's potential to facilitate white matter repair in CNS injury @scnpjournal doi.org/10.1017/neu.2026.100… Published with icons Beni Lerer, Steve Shoptaw and the late Dan Stein, the kindest giant in (cape) town. RIP 😢
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🧠🧬 Autoimmunity as an underexplored contributor to neuropsychiatric symptoms in 22q11.2 deletion syndrome A recent study synthesizes evidence linking autoimmune processes to the neuropsychiatric phenotype observed in 22q11.2 deletion syndrome (22q11DS).
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📄 Individuals with 22q11DS may develop • increased circulating autoantibodies & elevated inflammatory markers • increased BBB permeability • Converging evidence shows that antibodies targeting neural proteins can induce psychiatric symptoms
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🧩 Findings suggest Autoantibodies may represent an under-recognized source of vulnerability, acting alongside the genetic deletion 🔬 This perspective opens new directions for research and clinical consideration, including immunological screening doi.org/10.1017/neu.2025.100…

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How prevalent are behavioural addictions among adolescents? A newly published study in Acta Neuropsychiatrica suggests insights by examining multiple behavioral addictions simultaneously.
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It identifies strong links to underlying mental health: • Food addiction was tied to depression, anxiety, and stress. • Problematic internet use was linked to depression and stress. • Internet gaming disorder was associated with anxiety.
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The high rate of problematic internet use reflects the digitally immersive world. Findings underscore the deep connection between behavioral patterns and mental well-being. doi.org/10.1017/neu.2026.100…
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Decision-making in Borderline Personality Disorder (BPD) in Social Context A recent fMRI study used a multi-round Ultimatum Game to examine fairness, norm violations & value processing in individuals with BPD #BorderlinePersonalityDisorder #Neuroeconomics #SocialDecisionMaking
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These findings suggest that social impairments in BPD may be context-dependent, rather than pervasive Diff in behavior and neural processing may emerge primarily under stressful, disorder-relevant interpersonal contexts, rather than in neutral, one-shot interactions w/ strangers
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📌 Clinically, this supports a nuanced view of BPD: social difficulties may be amplified by interpersonal stress and emotional load, not by a global inability to process fairness or social norms. READ here for more: doi.org/10.1017/neu.2025.100…
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