Human Brain Contusions Contain Pathogenic Transmissible Species that Induce Progressive Cognitive Decline and Tau Pathology in Mice onlinelibrary.wiley.com/doi/…

Today we walk 🧡 At least 66 women have been killed in Australia in 2024 allegedly by male violence. This violence is preventable. A different future is possible but we need an acceleration of efforts across the spectrum of prevention, early intervention, responses & recovery. 🔸Details of the Walk available here respectvictoria.vic.gov.au/c…

A very important initiative to raise awareness and support victim-survivors @AbiAstridgeCla @TSnowRich @ChristieNeuro @STMneurosci

We are seeking participants for a study investigating the therapeutic potential of 4 weeks of aerobic exercise for common neurological repercussions of intimate partner violence #IPV   Click here to register interest redcap.link/bz6qss8r

Spitz et al. study long-term survivors of moderate-severe TBI, and show that elevated plasma levels of biomarkers related to neuronal damage are associated with white matter microstructure disruption on MRI and disordered cognition. tinyurl.com/bxnu5puz

Exclusive: Concussion risk in sport is well known, but research finds it is likely more common for victims of intimate partner violence. | @theheraldsun #IPV #concussion @STMneurosci @shultz_sandy heraldsun.com.au/news/victor…

The Australasian Neurotrauma Symposium will be held in Perth, WA over the weekend of November 30 - December 1. Registration and attendance at the event is free. More information on abstract submission and attendance is available here: ow.ly/biuk50TLlP9

What is happening in the brain longer-term after you hit your head (TBI/concussion)? Spitz and colleagues @Brain1878 walk us through plasma biomarkers and clinical neuropsychological outcomes in a fascinating new paper. academic.oup.com/brain/advan… Key Points: - We are becoming more and more concerned about concussion and whether blood biomarkers can be diagnostic and prognostic. - We need more data on long-term neuropathological processes after TBI. - The authors suggest that studying biomarkers in the chronic phase is 'vital.' - They focus on plasma biomarkers following TBI and zoom in on amyloid and tau PET, white matter microarchitecture, brain age and cognitive changes. - 90 folks with TBI in study. - Plasma UCH-L1 levels 67% higher. - P-tau181 27% higher. - Amyloid and tau PET normal. Higher P-tau181, UCH-L1, GFAP and NfL = worse white matter microstructure. - There were some changes in memory/cognitive measures. My take: The authors opine that collectively the findings MAY represent 'ongoing neuropathology' following a single moderate–severe TBI. Really great to read about the use of plasma biomarkers, imaging and clinical tests over time. My hope is that more groups will perform similar experiments, collect clinical outcomes and when appropriate collect post-mortem brains. The picture is complex, and it is interesting to think about what is happening in the brain longer-term following a concussion. academic.oup.com/brain/advan… #Parkinsons #TBI #concussion

How long does it take athletes’ brains to fully recover after a #concussion? Can blood biomarkers better estimate when they’re ready to play again? A study in @JAMANetworkOpen provides insight: bit.ly/3Y9Vzr9 #NeuroTwitter @McDonaldStu_ @UCLABrainSPORT @TeenaShettyMD

The NSW coercive control legislation comes into effect today. @DV_NSW anticipate it will lead to more people contacting specialist services for support. It is absolutely critical frontline services receive additional funding to ensure that everyone victim-survivor seeking support receives a response that meets their safety needs. dailytelegraph.com.au/truecr…

Thank you to @wtuohy for such a comprehensive article on our study released today, & to @hayleyboxall1 & @voccvic for their comments on our findings. Our study found that in 71% of the 235 cases of intimate partner femicide examined the male perpetrator had contact with at least 2 points of the criminal justice system prior to committing lethal violence. 👉🏼 Read @theage overview of our findings here: amp.theage.com.au/national/w…

Huge amount of work in this one - well done @Will_T_OBrien! Thanks to all of our colleagues and @VAFA_HQ partners and participants. @STMneurosci

Great article by @catherineordway & @GingerGorman calling for sport organisations & clubs to do more to address violence against women. They emphasise the importance of education & recommend codes implement the “no fault, stand down” rule similar to NRL. theconversation.com/a-minute…

“Addressing the national crisis of violence against women is everyone’s responsibility, and sporting codes and clubs have a really critical role to play.” @Kate_FitzGibbon @OurWatchAus @kirstyforsdike news.com.au/lifestyle/real-l… via @newscomauHQ

See the new feature documentary film on the work within our Clinical Psychedelic Lab @MonashUni streaming online here: sbs.com.au/ondemand/tv-progr… Deep gratitude for our skilled team & brave participants. (If overseas, use a vpn set to Australia) Monash.edu/psychedelics

A fantastic shout out for the value of the collaboration between the VAFA and the Monash University Sports Concussion Research team lead by @McDonaldStu_ @shultz_sandy generating high and applying quality evidence to improve the safety of participants in community football.

Yang & Yau et al. studied blood markers of vascular health in older adults and found that the plasma levels of two proteins involved in blood vessel formation predicted future Alzheimer’s disease pathology and cognitive decline. tinyurl.com/28f7eb5b

Venous blood dried onto blood spots (DBS) removes pre-analytical challenges that may limit🩸biomarkers. Our DBS method quantifies #AD biomarkers near to the acc. of plasma biomarkers (incl. #ptau217). A future tool for remote areas / distance 🏠 visits? alz-journals.onlinelibrary.w…