No matter how good your Leaky Gut protocol is, if there is ongoing exposure to toxins, there will be no healing
Downregulation of intestinal stem cell (ISCs) proliferation & differentiation, driven by inflammation, gut-dysbiosis, intestinal immune dysregulation, microbial endproducts, loss of paneth cell signaling will compromise healin long term
In studies of mycotoxin injury, giving binders to remove the exposure upregulated ISC function & regeneration of the epithelial layer
The same will go for antimicrobial protocols needed to fully get hold of the problem at hand, if the goal is long term solution of your problem, without over-reliance on supplements
Below is a list of support tools for ISC function (not exhaustive):