Joined February 2012
- Tweets 50
- Following 95
- Followers 51
- Likes 306
1 Photos and videos
steven tan retweeted
7 Mar 2023
I'm creating 3D tours of open single cell RNA-seq data in UMAP space. Here, using data from 50k brain cells by the @AllenInstitute . (portal.brain-map.org/atlases…). The UMAP position and class of every cell is read into Blender, realized as a stylized, class-specific model I sculpted
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steven tan retweeted
30 Jan 2023
Stylized illustration I made of CAR T-cells attacking a cancer cell. Created using Blender/Substance Painter/Photoshop. #sciart #Blender3d
ALT Illustration of CAR T-cells swarming a cancer cell, exposing it to cytotoxic molecules.
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steven tan retweeted
18 Jan 2023
Had fun working on this project characterizing the mechanical behavior of latrophilin-3 (Lphn3), a cell adhesion molecule that is important for excitatory synapse formation in the brain! Tweetorial below (1/5)
New preprint: @bri_zhong shows that pN forces can potentially activate latrophilin 3, an adhesion GPCR that regulates synaptic plasticity. A first step for the lab in understanding this fascinating class of signaling proteins. Congrats Brian!
t.ly/ETL_
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steven tan retweeted
19 Sep 2022
Code to determine colocalization and transformations are available here with demo data: github.com/newmanst/simca-pu…. Full Data available to public: purl.stanford.edu/bc494tq176…
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steven tan retweeted
14 Sep 2022
Check our new paper @NatureComms - We demonstrate a novel Single-Molecule Colocalization Assay (SiMCA) to eliminate background produced by non-specific binding. Great collaboration with @Dunn_Lab , co-lead by @AmaniHariri20 @SharonNewman0 @steventan17 doi.org/10.1038/s41467-022-3…
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steven tan retweeted
14 Sep 2022
Finally OUT!! 🥳Check our new paper “Improved immunoassay sensitivity and specificity using single-molecule colocalization”@NatureComms SiMCA uses the power of Single Molecule Fluorescence in sandwich-type bioassays #ScienceTwitter #fluorescence #SMFM #ELISA #SiMCArdWhynot ⬇️🔬🚦
14 Sep 2022
Check our new paper @NatureComms - We demonstrate a novel Single-Molecule Colocalization Assay (SiMCA) to eliminate background produced by non-specific binding. Great collaboration with @Dunn_Lab , co-lead by @AmaniHariri20 @SharonNewman0 @steventan17 doi.org/10.1038/s41467-022-3…
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steven tan retweeted
15 Jun 2022
Illustration I created for @A_Amunts as a stylized interpretation of his group's new findings in @Nature on the assembly of the mitoribosome. We eventually brought this illustration to life in the animation below. Paper link: nature.com/articles/s41586-0…
9 Jun 2022
Assembly of the human mitoribosome: Animation I created for @A_Amunts to represent his lab's mechanistic discoveries in their new publication in @Nature. Read the paper by Yuzuru Itoh, Anas Khawaja, Alexey Amunts, et al.: nature.com/articles/s41586-0…
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steven tan retweeted
9 May 2022
How do cadherin-catenin complexes interact cooperatively with F-actin to assemble into large, organized clusters observed in cells? Our new pre-print may provide some insight. Big shoutout to my co-first author @bax1337 for working with me on this! biorxiv.org/content/10.1101/… [1/3]
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steven tan retweeted
9 May 2022
So excited to share a preprint of my first, first-author paper! biorxiv.org/content/10.1101/… [1/4]
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steven tan retweeted
6 May 2022
If anyone's looking for a postdoc in Seattle, @claudiaraudia is an amazing scientist, inspiring mentor, and badass (pro!) ultimate player
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steven tan retweeted
3 May 2022
Short animation I made from one of my previous scientific illustrations: A little macrophage, getting ready to perform some phagocytosis and enjoy a picnic feast of bacteria and viruses. #SciArt #Blender3d
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steven tan retweeted
29 Apr 2022
I'm working on bringing some of my previous scientific illustrations to life as animations. Short animation stylizing the idea of CAR T-cell therapy; here, engineered T-cells conducting surveillance, searching for cancer cells to destroy. #sciart #Blender3d
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steven tan retweeted
19 Apr 2022
I created this illustration for @ljiresearch for an article describing research at LJI on the role of mucosa in immunity (bit.ly/3jBsrn6). The idea was to represent epithelia and epithelia-associated T-cells as a first line of defense against invading pathogens. #SciArt
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steven tan retweeted
12 Apr 2022
HOW do cells respond to being peeled off e.g. when you pinch yourself too hard? We find that once cells partly detach, newly extruded membrane tethers attached to the surface (e.g. retraction fibers) guide cells back to their original location tinyurl.com/mr3ajzsu 1/
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steven tan retweeted
12 Jan 2022
How do hundreds of species coexist in rainforests or your gut without driving each other extinct? Our new work shows how correlations among interspecies interactions, e.g. the enemy of my enemy is my friend, may help maintain the diversity of ecosystems tinyurl.com/mrxrhx3x 🧵
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4 Jan 2022
Excited to share my first preprint detailing our work on developing a new biosensor for visualizing mechanical forces across proteins in cells!
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steven tan retweeted
16 Dec 2021
It’s official now! Super excited to announce that I’ll be starting my Lab @UBC @UBCChem in 2023! If you’re interested in doing great interdisciplinary research in Canada BC 🇨🇦🇨🇦, please DM me!!🤩✨
15 Dec 2021
The Dept of Chemistry is pleased to announce the appointment of Dr. Amani Hariri as an Assistant Professor in the area of biological chemistry with a focus on biosensing. She will join the department January 1st , 2023. Read more about Dr. Hariri here: ow.ly/xCmh50HbLYa
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steven tan retweeted
8 Nov 2021
I like exploring creative ways to illustrate scientific ideas. This is an illustration I created to represent the idea of mechanotransduction: a process in which cells sense the mechanics of their environment.
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steven tan retweeted
19 Nov 2021
"Macrophage picnic." An illustration I created to represent the idea of a macrophage. Macrophages are cells in the immune system that consume foreign organisms, such as bacteria and viruses, through a process known as phagocytosis. #SciArt
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steven tan retweeted
4 Jan 2021
Excited to share my 1st co-authored paper with @_SungminNam published in @advsci, demonstrating cancer cells utilize protrusive extracellular force generation during mitosis, and not protease degradation or spreading, to drive mitotic elongation in collagen-rich matrix.
4 Jan 2021
💥New year, new paper! Read our latest paper by @_SungminNam and @yunghao24 titled “Cellular pushing forces during mitosis drive mitotic elongation in collagen gels” published in @AdvSciNews onlinelibrary.wiley.com/doi/…
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