the WRC guy

Joined July 2022
Photos and videos
stonechenlab retweeted
Excited to share the cryo-EM structure of the Retriever-SNX17 complex. We also identify additional ligands that bind to the same pocket in Retriever. Great collaboration with the Chen lab, UTSW SBL and the Turer lab. biorxiv.org/content/10.1101/…
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Very happy with the collaboration! Appreciate everyone's contributions!
I am delighted to share our findings describing the structural organization of Retriever - CCC: biorxiv.org/content/10.1101/… Congrats also to @PeterJCullen1 @brettcollins100 and Markku Varjosalo and teams who also tackled this question.
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Very exciting! Wonderful collaborations!
Very proud to have been able to be part of this: True multi-disciplinary effort to characterise the physical interaction of Arf1 with WRC… Arf GTPase activates the WAVE regulatory complex through a distinct binding site science.org/doi/10.1126/scia…
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stonechenlab retweeted
10 Oct 2022
PhD and postdoc positions in immune cell response and wound closure dynamics available - Bogdan lab at the Philipps-University of Marburg. If you are interested in, please apply via sven.bogdan@staff.uni-marburg.de. PIs please retweet!

ALT A novel in vivo single-cell wounding model of the abdominal epidermis in the early Drosophila pupa, see Lehne et al., 2022, Nat. Comms. https://www.nature.com/articles/s41467-022-30167-0

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stonechenlab retweeted
Structural basis for directional chitin biosynthesis nature.com/articles/s41586-0…

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stonechenlab retweeted
A great collaborative effort with @stonechenlab and @RottnerKlemens group! Congratulations to @bojian_ding for all the structural work and #cryoem and all the other authors.
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Our Rac1-WRC paper is published in Nature Communications today rdcu.be/cVI70, showing how Rac1 GTPase activates the WAVE complex to promote actin polymerization. Thanks a million to all co-authors for solving this important mechanism!!

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stonechenlab retweeted
Yesterday, undergrad scholars from the Biochemistry Undergraduate Research Program presented the fruit of their summer research experiences in the form of 3-min talks. Congratulations Braden, Charlie, Cheng, Ciaran, Grant, Lauren, Michelle, Prescott, and Zheng (Sam)!
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stonechenlab retweeted
Our structure of dynein-dynactin on microtubules is now out in @Nature! Thanks to @janetiwasa for this beautiful movie showing how cargos might use pairs of adaptors to recruit their motors. nature.com/articles/s41586-0…
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stonechenlab retweeted
Last week, we welcomed our new first-year class of Biochemistry PhD students! Welcome to @bbmbisu!
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first tweet?
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stonechenlab retweeted
Come join our growing #cryoEM community! Assistant professor position in the @bbmbisu department at Iowa State University. Our @CryoEM_ISU facility is eager to produce more beautiful structures like the one below! Apply here: isu.wd1.myworkdayjobs.com/en…
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