Joined April 2009
1 Photos and videos
I am deleting my Twitter account. Please follow me on BlueSky (@wnoble.bsky.social).
4
292
5
18
4,360
William Stafford Noble retweeted
Interested in de novo peptide sequencing from #massspec #proteomics data? Check out our latest #preprint about Casanovo! 👉 doi.org/10.1101/2023.01.03.5… That's right folks - it's time for another #tweetorial 🧵 (1/9)

3
19
123
41,739
William Stafford Noble retweeted
Want to learn more about the state of the art in de novo peptide sequencing at #ASMS2023? Come check out our: - Evening workshop #17 for a Casanovo tutorial on Monday - Talk at the AI session on Wednesday #TeamMassSpec
Interested in de novo peptide sequencing from #massspec #proteomics data? Check out our latest #preprint about Casanovo! 👉 doi.org/10.1101/2023.01.03.5… That's right folks - it's time for another #tweetorial 🧵 (1/9)
6
12
3,239
William Stafford Noble retweeted
Congratulations to Lincoln Harris on being awarded an NRSA fellowship!
2
7
1,223
William Stafford Noble retweeted
Check out Polarbear🐻‍❄️, a method to predict the missing scATAC-seq profiles just based on scRNA-seq, and vice versa. 🐻‍❄️ also derives matching in between scRNA-seq and scATAC-seq profiles, enabling integration of different types of single cell measurements. link.springer.com/chapter/10…
2
13
64
William Stafford Noble retweeted
Our paper about building spectral libraries from DIA data is officially out @JProteomeRes! Thank you to everyone who worked on this and to our reviewers for their feedback, I'm very excited about the final product.
Building Spectral Libraries from Narrow-Window Data-Independent Acquisition Mass Spectrometry Data #JProteomeRes pubs.acs.org/doi/10.1021/acs…
1
8
73
William Stafford Noble retweeted
13 May 2022
Obligatory post following a bioRxiv submission. In this work we show that 1) PSM-level FDR estimates in practice are invalid and 2) a simple variant of the peptide-level FDR estimate protocol can yield a significantly greater number of peptide detections
Detecting more peptides from bottom-up mass spectrometry data via peptide-level target-decoy competition | buff.ly/3wmZcKP #proteomics
2
11
30
The state of the art in de novo peptide sequencing has just advanced: meet Casanovo, a transformer model that translates from the sequence of peaks in a spectrum to the sequence of amino acids in a peptide. biorxiv.org/content/10.1101/…
5
43
185
William Stafford Noble retweeted
24 Jan 2022
Not going to lie. Part of the reason I created an account was to promote this preprint of mine. We have created a new score, MS1Connect, that measures the similarity between pairs of mass spectrometry runs solely using MS1 scans and without any peptide identifications. 🧵 1/9
MS1Connect: a mass spectrometry run similarity measure biorxiv.org/cgi/content/shor… #bioRxiv
3
17
62
Thanks for funding Percolator, CZI.
27 May 2020
#Opensource software is essential to science. That’s why we’re awarding 23 grants to support open source tools that accelerate biomedical research and serve the larger scientific community. chanzuckerberg.com/newsroom/…
1
24
My lab has an open position for a software developer to support our Percolator machine learning engine for mass spectrometry analysis. uwhires.admin.washington.edu…

1
20
40
William Stafford Noble retweeted
I'm honored to have received an @asmsnews postdoctoral career development award. asms.org/about-asms-awards/p… Big thanks to all my mentors (@KrisLaukens, @goethals, @thabangh, @Pdorrestein1) and collaborators (@compomics, @dtabb73, many more) over the years.
6
8
63
The MEME Suite of motif-based sequence analysis tools was the subject of my very first bioinformatics paper way back in 1996. The web server (meme-suite.org/) has been in operation ever since. Now you can install it directly on your Mac: "sudo port install memesuite"

4
48
251
I have postdoctoral positions in machine learning and genomics/proteomics available in my lab. noble.gs.washington.edu/post… Come find me if you are at #ISMBECCB19

60
78
William Stafford Noble retweeted
20 Feb 2019
The ENCODE imputation challenge is now live! Sign-up, form teams, and impute your way to cash awards sponsored by @LifeEpigenetics! synapse.org/encodeimpute

21
26