ATA's official monthly journal, is peer-reviewed for topics ranging from the molecular biology of the thyroid gland to clinical management of thyroid disorders.
Joined October 2018
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429 Photos and videos
Check out the @AmThyroidAssn new Multidisciplinary Consensus Statement on Ambulatory Thyroid Surgery, which outlines key strategies to ensure patient safety and optimal outcomes.
Read More: ow.ly/HaIJ50Z9yRm
#ThyroidJournal #medtwitter #endotwitter
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What links BRAFV600E and TERT in aggressive thyroid cancer? A team from @UofT identified DDX21 as a key mediator—driven by MAPK signaling-which partners with TERT to boost rRNA transcription and tumor growth, pointing to a new therapeutic target.
ow.ly/RXiN50Z3oHy
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Does active surveillance affect quality of life vs immediate surgery in low-risk PTC? A new @ThyroidJournal study from the Canadian Active Surveillance Study Group found similar QoL and anxiety at ~3 years ow.ly/MUVz50Z3oCc
@AmThyroidAssn #ThyroidJournal #medtwitter
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How does long-term iodine excess affect TSH? Does reducing iodine excess normalize TSH over time? A 20-year study suggests not—prior excess is linked to higher TSH/hypothyroidism, w/aging and iodine history interacting to shape long-term thyroid function.
ow.ly/KAzS50Z3opK
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Can 3D tools improve margin assessment in invasive thyroid cancer surgery? A team @IcahnMountSinai introduces MarginView3D, enabling real-time surgeon–pathologist collaboration—helping achieve precise resections in advanced disease.
ow.ly/5o5O50Z3ogo
@AmThyroidAssn
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Do patient perceptions influence the radioiodine experience? A new @ThyroidJournal study shows many patients forget key precautions yet add their own, reporting multiple side effects—suggesting beliefs strongly shape adherence and symptom burden.
ow.ly/ULzJ50Z3oa8
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Is active surveillance safe for recurrent thyroid cancer? A meta-analysis found ~23% progression, possibly underestimated to 35–70% due to follow-up loss - suggesting caution for AS, especially in patients with higher Tg or advanced stage. ow.ly/Mx0p50Z3o3Y
@AmThyroidAssn
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Do all RAS-positive thyroid nodules need surgery? A @UCalgary study found many are benign or low risk, with low growth rates on follow-up—supporting active surveillance as a safe alternative in selected patients. ow.ly/vkTG50Z3nOc
@AmThyroidAssn #ThyroidJournal
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Why do thyroid US risk stratification systems (RSS) perform differently? A study from Korea comparing 5 different RSSs found major variation in sensitivity/biopsy rates driven by differing criteria—highlighting need for a unified TIRADS system.
ow.ly/nNXn50Z2VLv
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Why is TPO expression reduced in thyroid cancer? A new @ThyroidJournal study shows DNA hypermethylation silences TPO via MBD2 recruitment;TPO methylation assays may accurately distinguish malignant from benign nodules-offering a promising diagnostic tool
ow.ly/RhRN50Z2Vpp
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Can rehab exercises help swallowing after thyroidectomy? A @ThyroidJournal RCT shows a 3-month program of neck, swallowing & voice exercises improved swallowing-related QoL at 1 and 6 months vs usual care—safe, with only mild early pain increase.
ow.ly/GxpB50Z2V1h
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What is the long-term thyroid impact of Rx for children with high-risk neuroblastoma? A new study found >50% of survivors developed thyroid toxicity-esp after molecular radiotherapy, immunotherapy, or busulfan, underscoring need for lifelong follow-up.
ow.ly/3EuC50Z2UIq
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Does levothyroxine treatment raise cardiovascular risk in women with hypothyroidism? In the SWAN cohort, @mettleson and coauthors report no increased risk of MI, stroke, HF, or revascularization in LT4-treated women vs those without thyroid disease. ow.ly/NCp650Z2QGA
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NEW pilot-grant program! 🔬 ATA is funding 15 early-career investigators with up to $10K for innovative thyroid research. Applications due May 15. Associate & Early Career Members—this is your opportunity! Apply: ow.ly/TRGv50YR6bF
#ThyroidResearch #ResearchGrant #ATA
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How can we measure quality of life in thyroid cancer survivors? A new @ThyroidJournal study introduces the TCQOLI—a validated, thyroid-cancer–specific utility index designed for QALY estimates, cost-effectiveness analyses, and patient-centered decisions. ow.ly/3UIK50YIi1o
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Does levothyroxine benefit older adults with subclinical hypothyroidism? In the Emulated Target Trial of >22,000 UK patients, authors from @sunderlanduni report lower CV events & all-cause mortality with LT4—esp. when TSH exceeded age-specific ranges. ow.ly/3lXm50YEFfF
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What are risks of permanent hypoparathyroidism after thyroidectomy? Recent study from Korea found higher rates of kidney stones, renal insufficiency & major cardiac events in patients with PO-hypoPT—highlighting need for ongoing renal & CV monitoring. ow.ly/kSFS50YEEPf
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Can neonatal fragment crystallizable receptor (FcRn) blockers assist in treatment of refractory Graves’ disease? New @ThyroidJournal case report describes rapid normalization of thyroid hormones wi/batoclimab & sustained euthyroidism after stopping therapy ow.ly/3y4s50Yx3gJ
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New options for BRAFV600E-negative anaplastic thyroid cancer? In a phase 2 @ThyroidJournal trial, anlotinib sintilimab achieved a 48% response rate & median PFS ~9.6 months, with manageable toxicity—supporting further study. ow.ly/ICpy50Yx35s
#ThyroidJournal #medtwitter
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When tumor tissue isn’t available in sporadic MTC, can liquid biopsy help? A @ThyroidJournal study shows plasma ctDNA reliably detected RET mutations in progressive, high–tumor burden cases—supporting its use to possibly guide RET inhibitor therapy. ow.ly/aX0Y50Yx2Pe
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