Synthetic Biologist | Biotech Entrepreneur | MIT Professor

Joined April 2007
9 Photos and videos
11 Dec 2025
RT @SentiBio: Dr. Kanya Rajangam, Chief Medical Officer, emphasized that the encouraging SENTI-202 data support advancement into pivotal st…
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10 Dec 2025
$SNTI recently reported our Logic Gated SENTI-202 cell therapy achieved 50% ORR, 42% CR/CRh, 7.6 month cCR durability in heavily pretreated refractory/refractory AML patients at #ASH25. This is an exciting new treatment modality for R/R AML, a disease with a median OS ~5 months
Dr. Nosha Farhadfar noted that SENTI-202 is demonstrating deep, durable responses and a favorable safety profile in R/R AML, underscoring its potential to selectively target AML cells while preserving healthy ones. bit.ly/3XFf7ST $SNTI #AML #ASH2025
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Timothy Lu retweeted
If you missed our CEO, Tim Lu, at the H.C. Wainwright 27th Annual Global Investment Conference, don’t worry — you can watch the full presentation now! 🎥 Replay available here: bit.ly/4mK46dE $SNTI #CellTherapy #AML #CARNK #AcuteMyeloidLeukemia

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Timothy Lu retweeted
Kanya Rajangam, MD, PhD, President and Chief Medical Officer of $SNTI, shares her excitement for the upcoming data presentation from the SENTI-202 trial at the AACR Annual Meeting being held April 25-30, 2025 bit.ly/3QYtOx5 @AACR
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Timothy Lu retweeted
#MarkYourCalendars: $SNTI leadership will host a conference call and webcast to discuss the new SENTI-202 Phase 1 clinical data being presented at #AACR2025 on Monday, April 28, 2025, at 8:30 AM ET. Access it here: bit.ly/3S668ap #CellTherapy #CARNK #AML @AACR
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Timothy Lu retweeted
Senti Bio to Showcase SENTI-202 Clinical Data and Novel Logic Gated Gene Circuit Mechanism of Action in Oral and Poster Presentations at the American Association for Cancer Research (AACR) Annual Meeting 2025 bit.ly/3QYtOx5 $SNTI #CellTherapy #CARNK @AACR #AACR25
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3 Apr 2025
Excited to share the latest clinical and preclinical data on our Logic Gated SENTI-202 product at the upcoming AACR meeting!
Kanya Rajangam, MD, PhD, President and Chief Medical Officer of $SNTI, shares her excitement for the upcoming data presentation from the SENTI-202 trial at the AACR Annual Meeting being held April 25-30, 2025 bit.ly/3QYtOx5 @AACR
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3 Dec 2024
Very excited to share details on SENTI-202 clinical trial - 2 of 3 pts achieved MRD negative CR in 1st dose level evaluated with a generally well-tolerated preliminary safety profile. Both patients continue to maintain remission (4 and 3 months, respectively). $SNTI
Today, we announced positive initial clinical data from the Phase 1 trial of SENTI-202, a potential first-in-class, off-the-shelf #CARNK #celltherapy for R/R hematologic malignancies, including #AML. Learn more on our webcast on Dec. 3 at 7:30am ET: bit.ly/4eUaKtb $SNTI
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3 Dec 2024
Excited to share the detailed data on SENTI-202 with Dr. Stephen Strickland and Dr. Kanya Rajangam. Join us to learn about how our #genecircuits enhanced CAR-NK therapies have the potential to transform the treatment of cancer through Logic Gating. $SNTI
Join us for a live webcast where Senti management and Dr. Stephen Strickland will discuss the positive initial clinical data from the Phase 1 clinical trial of SENTI-202, a Logic-Gated, selective CD33/FLT3-targeting #CARNK #celltherapy. Access here: bit.ly/4eUaKtb $SNTI
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Timothy Lu retweeted
Join us for a live webcast where Senti management and Dr. Stephen Strickland will discuss the positive initial clinical data from the Phase 1 clinical trial of SENTI-202, a Logic-Gated, selective CD33/FLT3-targeting #CARNK #celltherapy. Access here: bit.ly/4eUaKtb $SNTI
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28 Jun 2024
Congratulations to @SentiBio for its $8M award from California Institute for Regenerative Medicine (CIRM) for its Logic-Gated SENTI-202 clinical trial for relapsed/refractory AML. Thanks so much to CIRM for this support! $SNTI cirm.ca.gov/about-cirm/newsr…

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Timothy Lu retweeted
We @abscibio are excited to unveil IgDesign™ @NeurIPSConf and present our work at @workshopmlsb @AI4D3 @genbio_workshop! IgDesign is an antibody inverse folding model that we have experimentally validated in our lab. Read the paper here: biorxiv.org/content/10.1101/… #NeurIPS2023
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28 Aug 2023
Check out how $SNTI's Logic Gates precisely discriminate between cancer cells and healthy cells, allowing us to achieve highly precise cancer therapeutics! #synbio
At Senti, we envision a world where #cancer patients can access smarter therapies that precisely kill their cancer cells and spare their healthy cells. Watch to learn how we're utilizing our proprietary Logic Gating technology to design #CARNK cell therapies to achieve this goal.
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10 Aug 2023
Exciting times for @SentiBio as we gain extra fuel to power our Gene Circuit enhanced cell therapies to patients.
Today, we announced that Celadon Partners will acquire Senti’s manufacturing facility and CMC capabilities to establish GeneFab, an independent manufacturing business for cell and gene therapies. Learn more: bit.ly/3KzwjmH
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Timothy Lu retweeted
26 Jul 2023
Nature research paper: Sub-1.4 cm3 capsule for detecting labile inflammatory biomarkers in situ go.nature.com/44YF29F

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26 Jul 2023
Really excited to publish this work with Maria Eugenia Inda, Gio Traverso, Rabia Yazicigil, and other colleagues advancing a miniaturized pill with living cells for sense-and-respond in vivo!
26 Jul 2023
Nature research paper: Sub-1.4 cm3 capsule for detecting labile inflammatory biomarkers in situ go.nature.com/44YF29F
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14 Jun 2023
Congratulations to the @openprotein team and @tbepler1 on this exciting new publication. Opportunities for ML-driven protein design continue to grow!
14 Jun 2023
Excited to announce PoET, our (@timt1630, @tbepler1) retrieval-augmented generative protein language model that achieves state-of-the-art unsupervised variant function prediction performance on #ProteinGym. #MachineLearning #ProteinML 1/9 arxiv.org/abs/2306.06156
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